(20 nodes) Definitive hemopoiesis network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103353791	Sp3b transcription factor. (655 aa)
	LOC103370190	Ubiquitin-like domain-containing protein. (112 aa)
	gar1	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (228 aa)
	kri1	KRI1 homolog. (759 aa)
	sae1	SUMO1 activating enzyme subunit 1. (348 aa)
	cdk5rap3	CDK5 regulatory subunit associated protein 3. (503 aa)
	LOC103354886	Small ubiquitin-related modifier. (96 aa)
	mfap5	Microfibril associated protein 5. (128 aa)
	cbfb	Core-binding factor subunit beta. (188 aa)
	adar	Adenosine deaminase RNA specific. (1338 aa)
	LOC103358548	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	LOC103365158	T-cell acute lymphocytic leukemia 1. (388 aa)
	ube2i	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	mib1	Mindbomb E3 ubiquitin protein ligase 1. (1020 aa)
	LOC103353782	Ubiquitin-like domain-containing protein. (131 aa)
	LOC103353696	BHLH domain-containing protein. (458 aa)
	SP3	Sp3a transcription factor. (705 aa)
	ENSSPAP00000021526	BHLH domain-containing protein. (108 aa)
	LOC103366963	Small ubiquitin-related modifier. (101 aa)
	sumo2	Rad60-SLD domain-containing protein. (71 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000021526	LOC103353696	ENSSPAP00000021526	ENSSPAP00000016346	BHLH domain-containing protein.	BHLH domain-containing protein.	0.442
ENSSPAP00000021526	cbfb	ENSSPAP00000021526	ENSSPAP00000029069	BHLH domain-containing protein.	Core-binding factor subunit beta.	0.716
LOC103353696	ENSSPAP00000021526	ENSSPAP00000016346	ENSSPAP00000021526	BHLH domain-containing protein.	BHLH domain-containing protein.	0.442
LOC103353696	LOC103365158	ENSSPAP00000016346	ENSSPAP00000019223	BHLH domain-containing protein.	T-cell acute lymphocytic leukemia 1.	0.442
LOC103353696	cbfb	ENSSPAP00000016346	ENSSPAP00000029069	BHLH domain-containing protein.	Core-binding factor subunit beta.	0.700
LOC103353782	LOC103353791	ENSSPAP00000027383	ENSSPAP00000028113	Ubiquitin-like domain-containing protein.	Sp3b transcription factor.	0.528
LOC103353782	LOC103358548	ENSSPAP00000027383	ENSSPAP00000017820	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.977
LOC103353782	LOC103366963	ENSSPAP00000027383	ENSSPAP00000021261	Ubiquitin-like domain-containing protein.	Small ubiquitin-related modifier.	0.890
LOC103353782	SP3	ENSSPAP00000027383	ENSSPAP00000000606	Ubiquitin-like domain-containing protein.	Sp3a transcription factor.	0.530
LOC103353782	sae1	ENSSPAP00000027383	ENSSPAP00000002914	Ubiquitin-like domain-containing protein.	SUMO1 activating enzyme subunit 1.	0.963
LOC103353782	ube2i	ENSSPAP00000027383	ENSSPAP00000021849	Ubiquitin-like domain-containing protein.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.977
LOC103353791	LOC103353782	ENSSPAP00000028113	ENSSPAP00000027383	Sp3b transcription factor.	Ubiquitin-like domain-containing protein.	0.528
LOC103353791	LOC103354886	ENSSPAP00000028113	ENSSPAP00000028486	Sp3b transcription factor.	Small ubiquitin-related modifier.	0.528
LOC103353791	LOC103358548	ENSSPAP00000028113	ENSSPAP00000017820	Sp3b transcription factor.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.540
LOC103353791	LOC103366963	ENSSPAP00000028113	ENSSPAP00000021261	Sp3b transcription factor.	Small ubiquitin-related modifier.	0.600
LOC103353791	LOC103370190	ENSSPAP00000028113	ENSSPAP00000012745	Sp3b transcription factor.	Ubiquitin-like domain-containing protein.	0.528
LOC103353791	sumo2	ENSSPAP00000028113	ENSSPAP00000019746	Sp3b transcription factor.	Rad60-SLD domain-containing protein.	0.528
LOC103353791	ube2i	ENSSPAP00000028113	ENSSPAP00000021849	Sp3b transcription factor.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.540
LOC103354886	LOC103353791	ENSSPAP00000028486	ENSSPAP00000028113	Small ubiquitin-related modifier.	Sp3b transcription factor.	0.528
LOC103354886	LOC103358548	ENSSPAP00000028486	ENSSPAP00000017820	Small ubiquitin-related modifier.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.973