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adprhl1 adprhl1 adgra3 adgra3 LOC103360355 LOC103360355 wnt5b wnt5b stk11 stk11 LOC103373263 LOC103373263 ssna1 ssna1 sema5a sema5a LOC103376234 LOC103376234 LOC103365343 LOC103365343 med1 med1 nin nin LOC103367097 LOC103367097 ENSSPAP00000027951 ENSSPAP00000027951 LOC103371952 LOC103371952 LOC103354313 LOC103354313 ENSSPAP00000026885 ENSSPAP00000026885 ENSSPAP00000026857 ENSSPAP00000026857 slit2 slit2 LOC103360486 LOC103360486 LOC103372156 LOC103372156 LOC103362574 LOC103362574 llph llph EIF2AK4 EIF2AK4 vcl vcl LOC103368749 LOC103368749 ubap1 ubap1 LOC103368088 LOC103368088 sema7a sema7a ryk ryk cyfip1 cyfip1 SRF-2 SRF-2 LOC103374376 LOC103374376 nrn1l nrn1l impact impact LOC103353645 LOC103353645 LOC103369234 LOC103369234 fam53b fam53b LOC103373678 LOC103373678 cyfip2 cyfip2 LOC103376007 LOC103376007 ulk1 ulk1 LOC103362426 LOC103362426 KLHL12 KLHL12 ENSSPAP00000017356 ENSSPAP00000017356 LOC103357368 LOC103357368 LOC103364430 LOC103364430 LOC103359141 LOC103359141 LOC103354101 LOC103354101 fgf1 fgf1 LOC103371265 LOC103371265 sfrp2 sfrp2 spry1 spry1 FAM53B FAM53B bin3 bin3 LOC103367378 LOC103367378 ulk2 ulk2 ENSSPAP00000013436 ENSSPAP00000013436 slit1 slit1 ENSSPAP00000012851 ENSSPAP00000012851 ENSSPAP00000012246 ENSSPAP00000012246 LOC103366277 LOC103366277 c9orf72 c9orf72 LOC103374616 LOC103374616 tmem108 tmem108 flrt3 flrt3 ppp1r12a ppp1r12a SPAST SPAST LOC103363431 LOC103363431 LOC103363430 LOC103363430 spry2 spry2 LOC103374305 LOC103374305 ist1 ist1 ENSSPAP00000009155 ENSSPAP00000009155 LOC103369010 LOC103369010 ENSSPAP00000008941 ENSSPAP00000008941 mycbp2 mycbp2 LOC103374663 LOC103374663 PTK7 PTK7 SRF SRF LOC103368433 LOC103368433 LOC103367232 LOC103367232 LOC103362159 LOC103362159 thsd7a thsd7a TGFBR2 TGFBR2 spg11 spg11 SLIT1 SLIT1 ednra ednra vgll2 vgll2 LOC103364924 LOC103364924 nrn1 nrn1 LOC103371090 LOC103371090 dcx dcx CDH2 CDH2 LOC103368849 LOC103368849 tnn tnn LOC103372763 LOC103372763 tgfbr2 tgfbr2 LOC103355473 LOC103355473 LOC103358784 LOC103358784
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
adprhl1ADP-ribosylhydrolase like 1. (1067 aa)
adgra3Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family. (1352 aa)
LOC103360355Fibronectin leucine rich transmembrane protein 1. (686 aa)
wnt5bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (444 aa)
LOC103373263Transforming growth factor beta; Belongs to the TGF-beta family. (384 aa)
ssna1Sjogren syndrome nuclear autoantigen 1. (114 aa)
sema5aSema domain-containing protein. (1078 aa)
LOC103376234Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (694 aa)
LOC103365343LRRNT domain-containing protein. (136 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1827 aa)
ninNinein (GSK3B interacting protein). (1521 aa)
LOC103367097Vang-like protein. (525 aa)
ENSSPAP00000027951Cordon-bleu WH2 repeat protein. (956 aa)
LOC103371952Uncharacterized protein. (341 aa)
LOC103354313Uncharacterized protein; Belongs to the semaphorin family. (638 aa)
ENSSPAP00000026885Uncharacterized protein. (356 aa)
ENSSPAP00000026857Uncharacterized protein. (247 aa)
slit2Slit homolog 2 (Drosophila). (1375 aa)
LOC103360486Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (790 aa)
LOC103372156Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b. (1362 aa)
LOC103362574Si:ch211-113g11.6; Belongs to the semaphorin family. (613 aa)
llphLLP homolog, long-term synaptic facilitation factor. (126 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1658 aa)
vclVinculin b. (1066 aa)
LOC103368749Rho family GTPase 2. (234 aa)
ubap1Ubiquitin associated protein 1. (463 aa)
LOC103368088Neuropilin; Belongs to the neuropilin family. (932 aa)
sema7aSemaphorin 7A; Belongs to the semaphorin family. (683 aa)
rykReceptor like tyrosine kinase. (646 aa)
cyfip1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
SRF-2Serum response factor. (478 aa)
LOC103374376Slit homolog 3 (Drosophila). (999 aa)
nrn1lNeuritin 1-like a. (159 aa)
impactImpact RWD domain protein. (367 aa)
LOC103353645Unc-51 like autophagy activating kinase 1a. (899 aa)
LOC103369234Vang-like protein. (526 aa)
fam53bFamily with sequence similarity 53 member B. (423 aa)
LOC103373678BTB domain-containing protein. (514 aa)
cyfip2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1252 aa)
LOC103376007Protein phosphatase 1 regulatory subunit. (885 aa)
ulk1Unc-51 like autophagy activating kinase 1. (1025 aa)
LOC103362426Endothelin receptor type Ab. (313 aa)
KLHL12Kelch like family member 12. (598 aa)
ENSSPAP00000017356Uncharacterized protein. (245 aa)
LOC103357368Neuropilin; Belongs to the neuropilin family. (846 aa)
LOC103364430Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2340 aa)
LOC103359141Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (149 aa)
LOC103354101Doublecortin-like kinase 1a. (675 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (181 aa)
LOC103371265Sema domain-containing protein. (1081 aa)
sfrp2Secreted frizzled-related protein 2. (295 aa)
spry1Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (360 aa)
FAM53BFamily with sequence similarity 53 member B. (451 aa)
bin3Bridging integrator 3. (253 aa)
LOC103367378Sema domain-containing protein. (1130 aa)
ulk2Unc-51 like autophagy activating kinase 2. (1026 aa)
ENSSPAP00000013436Sperm associated antigen 6. (229 aa)
slit1Uncharacterized protein. (1512 aa)
ENSSPAP00000012851Uncharacterized protein. (127 aa)
ENSSPAP00000012246Leucine zipper, putative tumor suppressor family member 3b. (630 aa)
LOC103366277Neuritin 1-like b. (166 aa)
c9orf72Zgc:100846. (462 aa)
LOC103374616Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2579 aa)
tmem108Transmembrane protein 108. (532 aa)
flrt3Fibronectin leucine rich transmembrane 3. (650 aa)
ppp1r12aProtein phosphatase 1 regulatory subunit. (1081 aa)
SPASTSpastin; Belongs to the AAA ATPase family. (477 aa)
LOC103363431Doublecortin-like kinase 1b. (706 aa)
LOC103363430Spartin b. (604 aa)
spry2Sprouty RTK signaling antagonist 2. (353 aa)
LOC103374305Fibronectin type-III domain-containing protein. (702 aa)
ist1IST1 factor associated with ESCRT-III. (348 aa)
ENSSPAP00000009155Mesoderm posterior ba. (132 aa)
LOC103369010Vinculin a. (1126 aa)
ENSSPAP00000008941Si:dkey-33o22.1. (89 aa)
mycbp2MYC binding protein 2. (4643 aa)
LOC103374663TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (587 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1081 aa)
SRFSerum response factor. (601 aa)
LOC103368433Colony stimulating factor 1b (macrophage). (270 aa)
LOC103367232Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
LOC103362159Survival of motor neuron 1, telomeric. (283 aa)
thsd7aThrombospondin, type I, domain containing 7Aa. (1590 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
spg11SPG11 vesicle trafficking associated, spatacsin. (2405 aa)
SLIT1Slit guidance ligand 1. (829 aa)
ednraEndothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (451 aa)
vgll2Vestigial-like family member 2a. (290 aa)
LOC103364924Rho family GTPase 2. (230 aa)
nrn1Neuritin 1a. (143 aa)
LOC103371090Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (805 aa)
dcxUncharacterized protein. (351 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
LOC103368849T-box transcription factor Ta. (398 aa)
tnnTenascin N. (1121 aa)
LOC103372763Uncharacterized protein. (638 aa)
tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (583 aa)
LOC103355473Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (918 aa)
LOC103358784Endothelin 2. (162 aa)
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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