(57 nodes) Positive regulation of small molecule metabolic process network (Stegastes partitus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103362339	Interleukin-1. (247 aa)
	LOC103354637	Guanylate cyclase activator 1d. (185 aa)
	srebf1	Sterol regulatory element binding transcription factor 1. (1178 aa)
	nr1h4	Nuclear receptor subfamily 1, group H, member 4. (485 aa)
	ENSSPAP00000013416	Uncharacterized protein. (504 aa)
	ddb1	Damage-specific DNA binding protein 1. (1085 aa)
	LOC103375265	SREBF chaperone. (787 aa)
	prxl2c	Peroxiredoxin like 2C. (225 aa)
	ENSSPAP00000011040	Nuclear receptor subfamily 1, group H, member 5. (378 aa)
	podn	Podocan. (593 aa)
	LOC103374137	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (384 aa)
	LOC103362897	Si:ch211-103a14.5. (190 aa)
	PPARG	Peroxisome proliferator activated receptor gamma. (564 aa)
	prkaa2	Non-specific serine/threonine protein kinase. (557 aa)
	mlycd	Malonyl-CoA decarboxylase. (504 aa)
	clybl	Citrate lyase beta like. (347 aa)
	srebf2	Sterol regulatory element binding transcription factor 2. (1183 aa)
	ppard	Peroxisome proliferator-activated receptor delta b. (510 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (695 aa)
	ENSSPAP00000007645	Uncharacterized protein. (94 aa)
	ENSSPAP00000004940	Uncharacterized protein. (490 aa)
	p2rx7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (578 aa)
	zbtb20	Zinc finger and BTB domain containing 20. (680 aa)
	igf2	Insulin-like growth factor 2b. (215 aa)
	LOC103376574	Nuclear receptor subfamily 1, group D, member 4b. (571 aa)
	bend3	BEN domain containing 3. (820 aa)
	ncs1	Neuronal calcium sensor 1a. (190 aa)
	lpgat1	Lysophosphatidylglycerol acyltransferase 1. (372 aa)
	ENSSPAP00000019170	Apolipoprotein Ea. (259 aa)
	ppargc1a	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (1275 aa)
	MTLN	Mitoregulin. (123 aa)
	LOC103359141	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (149 aa)
	P2RY6	Pyrimidinergic receptor P2Y6. (365 aa)
	fgf1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (181 aa)
	pid1	Phosphotyrosine interaction domain containing 1. (225 aa)
	LOC103370335	ABC transporter domain-containing protein. (631 aa)
	ptgs2	Prostaglandin-endoperoxide synthase 2b. (608 aa)
	abcg4	ATP-binding cassette, sub-family G (WHITE), member 4a. (609 aa)
	ENSSPAP00000021681	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	abcd2	ATP-binding cassette, sub-family D (ALD), member 2. (737 aa)
	ppara	Peroxisome proliferator-activated receptor alpha a. (477 aa)
	htr2a	5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a. (493 aa)
	apoa4	Uncharacterized protein. (235 aa)
	nr1h3	Nuclear receptor subfamily 1, group H, member 3. (464 aa)
	ENSSPAP00000024435	Uncharacterized protein. (108 aa)
	LOC103376517	Uncharacterized protein. (107 aa)
	nr1d1	Nuclear receptor subfamily 1, group d, member 1. (514 aa)
	guca1b	Guanylate cyclase activator 1B. (197 aa)
	LOC103358093	Guanylate cyclase activator 1A. (207 aa)
	ENSSPAP00000026497	Ig-like domain-containing protein. (218 aa)
	ENSSPAP00000026899	Uncharacterized protein. (134 aa)
	prkaa1	Non-specific serine/threonine protein kinase. (573 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha b. (473 aa)
	rusc1	RUN and SH3 domain containing 1. (594 aa)
	dab2	DAB adaptor protein 2. (787 aa)
	ABCG1	ATP binding cassette subfamily G member 1. (395 aa)
	LOC103362117	Si:dkey-6n21.13; Belongs to the G-protein coupled receptor 1 family. (476 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCG1	PPARA	ENSSPAP00000030100	ENSSPAP00000027380	ATP binding cassette subfamily G member 1.	Peroxisome proliferator-activated receptor alpha b.	0.405
ABCG1	PPARG	ENSSPAP00000030100	ENSSPAP00000010481	ATP binding cassette subfamily G member 1.	Peroxisome proliferator activated receptor gamma.	0.416
ABCG1	apoa4	ENSSPAP00000030100	ENSSPAP00000024179	ATP binding cassette subfamily G member 1.	Uncharacterized protein.	0.709
ABCG1	nr1h3	ENSSPAP00000030100	ENSSPAP00000024288	ATP binding cassette subfamily G member 1.	Nuclear receptor subfamily 1, group H, member 3.	0.672
ABCG1	srebf2	ENSSPAP00000030100	ENSSPAP00000009526	ATP binding cassette subfamily G member 1.	Sterol regulatory element binding transcription factor 2.	0.519
ENSSPAP00000011040	LOC103376574	ENSSPAP00000011040	ENSSPAP00000000751	Nuclear receptor subfamily 1, group H, member 5.	Nuclear receptor subfamily 1, group D, member 4b.	0.429
ENSSPAP00000011040	PPARA	ENSSPAP00000011040	ENSSPAP00000027380	Nuclear receptor subfamily 1, group H, member 5.	Peroxisome proliferator-activated receptor alpha b.	0.476
ENSSPAP00000011040	PPARG	ENSSPAP00000011040	ENSSPAP00000010481	Nuclear receptor subfamily 1, group H, member 5.	Peroxisome proliferator activated receptor gamma.	0.476
ENSSPAP00000011040	nr1d1	ENSSPAP00000011040	ENSSPAP00000025193	Nuclear receptor subfamily 1, group H, member 5.	Nuclear receptor subfamily 1, group d, member 1.	0.429
ENSSPAP00000011040	ppara	ENSSPAP00000011040	ENSSPAP00000022603	Nuclear receptor subfamily 1, group H, member 5.	Peroxisome proliferator-activated receptor alpha a.	0.425
ENSSPAP00000011040	ppargc1a	ENSSPAP00000011040	ENSSPAP00000031370	Nuclear receptor subfamily 1, group H, member 5.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.943
ENSSPAP00000011040	sirt1	ENSSPAP00000011040	ENSSPAP00000008507	Nuclear receptor subfamily 1, group H, member 5.	Deacetylase sirtuin-type domain-containing protein.	0.594
ENSSPAP00000011040	srebf1	ENSSPAP00000011040	ENSSPAP00000014408	Nuclear receptor subfamily 1, group H, member 5.	Sterol regulatory element binding transcription factor 1.	0.480
ENSSPAP00000011040	srebf2	ENSSPAP00000011040	ENSSPAP00000009526	Nuclear receptor subfamily 1, group H, member 5.	Sterol regulatory element binding transcription factor 2.	0.480
ENSSPAP00000019170	LOC103362339	ENSSPAP00000019170	ENSSPAP00000015284	Apolipoprotein Ea.	Interleukin-1.	0.509
ENSSPAP00000019170	apoa4	ENSSPAP00000019170	ENSSPAP00000024179	Apolipoprotein Ea.	Uncharacterized protein.	0.851
ENSSPAP00000019170	nr1h3	ENSSPAP00000019170	ENSSPAP00000024288	Apolipoprotein Ea.	Nuclear receptor subfamily 1, group H, member 3.	0.494
ENSSPAP00000026497	ddb1	ENSSPAP00000026497	ENSSPAP00000013106	Ig-like domain-containing protein.	Damage-specific DNA binding protein 1.	0.427
ENSSPAP00000026899	LOC103375265	ENSSPAP00000026899	ENSSPAP00000012226	Uncharacterized protein.	SREBF chaperone.	0.899
ENSSPAP00000026899	abcd2	ENSSPAP00000026899	ENSSPAP00000022277	Uncharacterized protein.	ATP-binding cassette, sub-family D (ALD), member 2.	0.476