(22 nodes) Necrotic cell death network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103358823	Cylindromatosis (turban tumor syndrome), b. (681 aa)
	LOC103368198	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (439 aa)
	fadd	Uncharacterized protein. (191 aa)
	LOC103361989	Ninjurin 1. (142 aa)
	cyld	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (917 aa)
	LOC103360880	Uncharacterized protein. (330 aa)
	LOC103354167	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (263 aa)
	alkbh7	AlkB homolog 7. (230 aa)
	LOC103355780	Uncharacterized protein. (897 aa)
	gsdme	Gasdermin Eb. (405 aa)
	itpk1	Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family. (396 aa)
	bax	BCL2 associated X, apoptosis regulator a. (192 aa)
	ipmk	Kinase; Belongs to the inositol phosphokinase (IPK) family. (496 aa)
	ENSSPAP00000014743	Receptor-interacting serine-threonine kinase 3. (328 aa)
	LOC103372980	Protein kinase domain-containing protein. (337 aa)
	LOC103357298	Cylindromatosis (turban tumor syndrome), like; Belongs to the peptidase C19 family. (773 aa)
	irf3	Interferon regulatory factor 3. (463 aa)
	ripk1	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (687 aa)
	ENSSPAP00000003941	Pkinase_Tyr domain-containing protein. (403 aa)
	LOC103371706	Uncharacterized protein. (483 aa)
	LOC103364875	Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family. (404 aa)
	LOC103369383	Uncharacterized protein. (165 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000003941	ENSSPAP00000014743	ENSSPAP00000003941	ENSSPAP00000014743	Pkinase_Tyr domain-containing protein.	Receptor-interacting serine-threonine kinase 3.	0.986
ENSSPAP00000003941	LOC103354167	ENSSPAP00000003941	ENSSPAP00000019491	Pkinase_Tyr domain-containing protein.	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	0.424
ENSSPAP00000003941	LOC103355780	ENSSPAP00000003941	ENSSPAP00000016465	Pkinase_Tyr domain-containing protein.	Uncharacterized protein.	0.485
ENSSPAP00000003941	LOC103357298	ENSSPAP00000003941	ENSSPAP00000011276	Pkinase_Tyr domain-containing protein.	Cylindromatosis (turban tumor syndrome), like; Belongs to the peptidase C19 family.	0.506
ENSSPAP00000003941	LOC103358823	ENSSPAP00000003941	ENSSPAP00000002372	Pkinase_Tyr domain-containing protein.	Cylindromatosis (turban tumor syndrome), b.	0.506
ENSSPAP00000003941	LOC103360880	ENSSPAP00000003941	ENSSPAP00000019898	Pkinase_Tyr domain-containing protein.	Uncharacterized protein.	0.581
ENSSPAP00000003941	LOC103368198	ENSSPAP00000003941	ENSSPAP00000029165	Pkinase_Tyr domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.985
ENSSPAP00000003941	bax	ENSSPAP00000003941	ENSSPAP00000015004	Pkinase_Tyr domain-containing protein.	BCL2 associated X, apoptosis regulator a.	0.422
ENSSPAP00000003941	cyld	ENSSPAP00000003941	ENSSPAP00000026507	Pkinase_Tyr domain-containing protein.	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	0.506
ENSSPAP00000003941	fadd	ENSSPAP00000003941	ENSSPAP00000028894	Pkinase_Tyr domain-containing protein.	Uncharacterized protein.	0.696
ENSSPAP00000003941	irf3	ENSSPAP00000003941	ENSSPAP00000008064	Pkinase_Tyr domain-containing protein.	Interferon regulatory factor 3.	0.409
ENSSPAP00000003941	ripk1	ENSSPAP00000003941	ENSSPAP00000006343	Pkinase_Tyr domain-containing protein.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.831
ENSSPAP00000014743	ENSSPAP00000003941	ENSSPAP00000014743	ENSSPAP00000003941	Receptor-interacting serine-threonine kinase 3.	Pkinase_Tyr domain-containing protein.	0.986
ENSSPAP00000014743	LOC103354167	ENSSPAP00000014743	ENSSPAP00000019491	Receptor-interacting serine-threonine kinase 3.	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	0.577
ENSSPAP00000014743	LOC103355780	ENSSPAP00000014743	ENSSPAP00000016465	Receptor-interacting serine-threonine kinase 3.	Uncharacterized protein.	0.665
ENSSPAP00000014743	LOC103357298	ENSSPAP00000014743	ENSSPAP00000011276	Receptor-interacting serine-threonine kinase 3.	Cylindromatosis (turban tumor syndrome), like; Belongs to the peptidase C19 family.	0.675
ENSSPAP00000014743	LOC103358823	ENSSPAP00000014743	ENSSPAP00000002372	Receptor-interacting serine-threonine kinase 3.	Cylindromatosis (turban tumor syndrome), b.	0.675
ENSSPAP00000014743	LOC103360880	ENSSPAP00000014743	ENSSPAP00000019898	Receptor-interacting serine-threonine kinase 3.	Uncharacterized protein.	0.696
ENSSPAP00000014743	LOC103368198	ENSSPAP00000014743	ENSSPAP00000029165	Receptor-interacting serine-threonine kinase 3.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.833
ENSSPAP00000014743	LOC103372980	ENSSPAP00000014743	ENSSPAP00000011604	Receptor-interacting serine-threonine kinase 3.	Protein kinase domain-containing protein.	0.986