STRINGSTRING
irx1 irx1 tmem59l tmem59l irx3 irx3 ahi1 ahi1 tcf21 tcf21 ENSSPAP00000018277 ENSSPAP00000018277 pkd1 pkd1 LOC103359141 LOC103359141 fgf1 fgf1 LOC103364526 LOC103364526 ctnnbip1 ctnnbip1 LOC103375273 LOC103375273 ENSSPAP00000012246 ENSSPAP00000012246 LOC103365674 LOC103365674 lhx1 lhx1 ENSSPAP00000009545 ENSSPAP00000009545 LOC103366223 LOC103366223 ILK ILK gdnf gdnf wt1 wt1 LOC103361651 LOC103361651 klhl2 klhl2 LOC103354479 LOC103354479 LOC103358884 LOC103358884 SMAD4 SMAD4 hs2st1 hs2st1 LOC103374507 LOC103374507 klhl3 klhl3 LOC103376234 LOC103376234 wnt6 wnt6 smo smo bmp4 bmp4 GREM1 GREM1 greb1 greb1 efhc2 efhc2 LOC103369302 LOC103369302
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
irx1Iroquois homeobox 1b. (444 aa)
tmem59lTransmembrane protein 59-like. (343 aa)
irx3Iroquois homeobox 3a. (424 aa)
ahi1Abelson helper integration site 1. (1215 aa)
tcf21Transcription factor 21. (173 aa)
ENSSPAP00000018277Polycystic kidney disease 1b. (3029 aa)
pkd1Polycystic kidney disease 1a. (4558 aa)
LOC103359141Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (149 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (181 aa)
LOC103364526Bone morphogenetic protein 16. (476 aa)
ctnnbip1Catenin, beta interacting protein 1. (81 aa)
LOC103375273COMM domain containing 5. (211 aa)
ENSSPAP00000012246Leucine zipper, putative tumor suppressor family member 3b. (630 aa)
LOC103365674Heparan sulfate 2-O-sulfotransferase 1b. (357 aa)
lhx1LIM homeobox 1a. (316 aa)
ENSSPAP00000009545LIM zinc-binding domain-containing protein. (68 aa)
LOC103366223Iroquois homeobox 1a. (501 aa)
ILKIntegrin linked kinase. (454 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (254 aa)
wt1WT1 transcription factor b. (426 aa)
LOC103361651Mothers against decapentaplegic homolog. (503 aa)
klhl2Kelch-like family member 2. (605 aa)
LOC103354479Uncharacterized protein. (452 aa)
LOC103358884Mothers against decapentaplegic homolog. (651 aa)
SMAD4Mothers against decapentaplegic homolog. (528 aa)
hs2st1Heparan sulfate 2-O-sulfotransferase 1a. (361 aa)
LOC103374507Mothers against decapentaplegic homolog. (472 aa)
klhl3Kelch-like family member 3. (604 aa)
LOC103376234Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (694 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (824 aa)
bmp4Bone morphogenetic protein 4. (403 aa)
GREM1Gremlin; Belongs to the DAN family. (172 aa)
greb1Growth regulating estrogen receptor binding 1. (1766 aa)
efhc2EF-hand domain (C-terminal) containing 2. (676 aa)
LOC103369302WT1 transcription factor a. (432 aa)
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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