(24 nodes) Cellular senescence network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mapkapk5	MAPK activated protein kinase 5. (471 aa)
	LOC103361111	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (124 aa)
	becn1	Beclin 1, autophagy related. (447 aa)
	LOC103362742	Uncharacterized protein. (120 aa)
	SRF	Serum response factor. (601 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (695 aa)
	ecrg4	ECRG4 augurin precursor b. (145 aa)
	smc5	Structural maintenance of chromosomes 5. (1075 aa)
	tbx3	T-box transcription factor 3a. (715 aa)
	ENSSPAP00000011206	High mobility group AT-hook 2. (108 aa)
	LOC103362281	MAX network transcriptional repressor b. (611 aa)
	id2	Inhibitor of DNA binding 2a. (136 aa)
	mnt	MAX network transcriptional repressor a. (614 aa)
	prelp	Proline/arginine-rich end leucine-rich repeat protein. (382 aa)
	LOC103374781	T-box transcription factor 3b. (569 aa)
	smc6	Si:dkey-119f1.1. (1088 aa)
	ENSSPAP00000017877	Uncharacterized protein. (1285 aa)
	SRF-2	Serum response factor. (478 aa)
	wnt16	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
	spns1	Spinster homolog 1 (Drosophila). (515 aa)
	LOC103364213	Structural maintenance of chromosomes 6. (896 aa)
	nsmce2	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (230 aa)
	LOC103376272	High mobility group protein HMG-I/HMG-Y-like. (91 aa)
	LOC103355299	Uncharacterized protein. (91 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000011206	LOC103355299	ENSSPAP00000011206	ENSSPAP00000000167	High mobility group AT-hook 2.	Uncharacterized protein.	0.641
ENSSPAP00000011206	LOC103376272	ENSSPAP00000011206	ENSSPAP00000029810	High mobility group AT-hook 2.	High mobility group protein HMG-I/HMG-Y-like.	0.641
ENSSPAP00000017877	LOC103361111	ENSSPAP00000017877	ENSSPAP00000000950	Uncharacterized protein.	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).	0.602
ENSSPAP00000017877	LOC103364213	ENSSPAP00000017877	ENSSPAP00000025294	Uncharacterized protein.	Structural maintenance of chromosomes 6.	0.469
ENSSPAP00000017877	smc5	ENSSPAP00000017877	ENSSPAP00000009826	Uncharacterized protein.	Structural maintenance of chromosomes 5.	0.554
ENSSPAP00000017877	smc6	ENSSPAP00000017877	ENSSPAP00000015621	Uncharacterized protein.	Si:dkey-119f1.1.	0.469
LOC103355299	ENSSPAP00000011206	ENSSPAP00000000167	ENSSPAP00000011206	Uncharacterized protein.	High mobility group AT-hook 2.	0.641
LOC103355299	LOC103362742	ENSSPAP00000000167	ENSSPAP00000007917	Uncharacterized protein.	Uncharacterized protein.	0.659
LOC103361111	ENSSPAP00000017877	ENSSPAP00000000950	ENSSPAP00000017877	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).	Uncharacterized protein.	0.602
LOC103361111	becn1	ENSSPAP00000000950	ENSSPAP00000003669	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).	Beclin 1, autophagy related.	0.426
LOC103361111	sirt1	ENSSPAP00000000950	ENSSPAP00000008507	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).	Deacetylase sirtuin-type domain-containing protein.	0.589
LOC103362281	LOC103374781	ENSSPAP00000011762	ENSSPAP00000015470	MAX network transcriptional repressor b.	T-box transcription factor 3b.	0.486
LOC103362281	sirt1	ENSSPAP00000011762	ENSSPAP00000008507	MAX network transcriptional repressor b.	Deacetylase sirtuin-type domain-containing protein.	0.562
LOC103362281	tbx3	ENSSPAP00000011762	ENSSPAP00000010668	MAX network transcriptional repressor b.	T-box transcription factor 3a.	0.486
LOC103362742	LOC103355299	ENSSPAP00000007917	ENSSPAP00000000167	Uncharacterized protein.	Uncharacterized protein.	0.659
LOC103362742	LOC103376272	ENSSPAP00000007917	ENSSPAP00000029810	Uncharacterized protein.	High mobility group protein HMG-I/HMG-Y-like.	0.659
LOC103364213	ENSSPAP00000017877	ENSSPAP00000025294	ENSSPAP00000017877	Structural maintenance of chromosomes 6.	Uncharacterized protein.	0.469
LOC103364213	nsmce2	ENSSPAP00000025294	ENSSPAP00000029088	Structural maintenance of chromosomes 6.	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.	0.985
LOC103364213	smc5	ENSSPAP00000025294	ENSSPAP00000009826	Structural maintenance of chromosomes 6.	Structural maintenance of chromosomes 5.	0.989
LOC103374781	LOC103362281	ENSSPAP00000015470	ENSSPAP00000011762	T-box transcription factor 3b.	MAX network transcriptional repressor b.	0.486