(39 nodes) Positive regulation of DNA biosynthetic process network (Stegastes partitus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	pnkp	Polynucleotide kinase 3'-phosphatase. (607 aa)
	LOC103355474	Replication factor C (activator 1) 4. (330 aa)
	RFC4	Replication factor C subunit 4. (326 aa)
	wrap53	WD repeat containing, antisense to TP53. (488 aa)
	gins4	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa)
	mapkapk5	MAPK activated protein kinase 5. (471 aa)
	dkc1	Dyskeratosis congenita 1, dyskerin. (524 aa)
	atr	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2496 aa)
	ENSSPAP00000004083	Telo_bind domain-containing protein. (212 aa)
	xrcc5	X-ray repair complementing defective repair in Chinese hamster cells 5. (769 aa)
	rfc2	Replication factor C (activator 1) 2. (352 aa)
	LOC103356110	Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (537 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (439 aa)
	gins2	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa)
	cct3	T-complex protein 1 subunit gamma. (540 aa)
	nvl	Nuclear VCP like. (886 aa)
	ENSSPAP00000028301	Telo_bind domain-containing protein. (326 aa)
	nox4	FAD-binding FR-type domain-containing protein. (559 aa)
	chtf8	CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (130 aa)
	ENSSPAP00000026515	Cytochrome P450, family 1, subfamily C, polypeptide 2; Belongs to the cytochrome P450 family. (523 aa)
	LOC103357016	Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (523 aa)
	GREM1	Gremlin; Belongs to the DAN family. (172 aa)
	pdgfb	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (569 aa)
	atm	Non-specific serine/threonine protein kinase. (3048 aa)
	acd	Uncharacterized protein. (471 aa)
	rfc5	Replication factor C (activator 1) 5. (335 aa)
	grem1	Gremlin 1a, DAN family BMP antagonist. (179 aa)
	cct5	Chaperonin containing TCP1, subunit 5 (epsilon). (541 aa)
	polg2	Polymerase (DNA directed), gamma 2, accessory subunit. (453 aa)
	nek2	NIMA-related kinase 2. (429 aa)
	LOC103358541	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (520 aa)
	chtf18	AAA domain-containing protein. (922 aa)
	cct2	Chaperonin containing TCP1, subunit 2 (beta). (535 aa)
	gfer	Sulfhydryl oxidase. (196 aa)
	rfc3	Replication factor C (activator 1) 3. (356 aa)
	LOC103363473	Regulator of cell cycle. (126 aa)
	map3k4	Mitogen-activated protein kinase kinase kinase 4. (1587 aa)
	gins3	GINS complex subunit 3. (211 aa)
	fbxo4	F-box protein 4. (407 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000004083	LOC103355474	ENSSPAP00000004083	ENSSPAP00000000463	Telo_bind domain-containing protein.	Replication factor C (activator 1) 4.	0.619
ENSSPAP00000004083	RFC4	ENSSPAP00000004083	ENSSPAP00000000536	Telo_bind domain-containing protein.	Replication factor C subunit 4.	0.619
ENSSPAP00000004083	acd	ENSSPAP00000004083	ENSSPAP00000022047	Telo_bind domain-containing protein.	Uncharacterized protein.	0.983
ENSSPAP00000004083	dkc1	ENSSPAP00000004083	ENSSPAP00000003556	Telo_bind domain-containing protein.	Dyskeratosis congenita 1, dyskerin.	0.706
ENSSPAP00000004083	rfc2	ENSSPAP00000004083	ENSSPAP00000005522	Telo_bind domain-containing protein.	Replication factor C (activator 1) 2.	0.644
ENSSPAP00000004083	rfc3	ENSSPAP00000004083	ENSSPAP00000015957	Telo_bind domain-containing protein.	Replication factor C (activator 1) 3.	0.693
ENSSPAP00000004083	rfc5	ENSSPAP00000004083	ENSSPAP00000021139	Telo_bind domain-containing protein.	Replication factor C (activator 1) 5.	0.644
ENSSPAP00000004083	wrap53	ENSSPAP00000004083	ENSSPAP00000000715	Telo_bind domain-containing protein.	WD repeat containing, antisense to TP53.	0.686
ENSSPAP00000026515	atm	ENSSPAP00000026515	ENSSPAP00000022487	Cytochrome P450, family 1, subfamily C, polypeptide 2; Belongs to the cytochrome P450 family.	Non-specific serine/threonine protein kinase.	0.532
ENSSPAP00000026515	atr	ENSSPAP00000026515	ENSSPAP00000003683	Cytochrome P450, family 1, subfamily C, polypeptide 2; Belongs to the cytochrome P450 family.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.433
ENSSPAP00000028301	LOC103355474	ENSSPAP00000028301	ENSSPAP00000000463	Telo_bind domain-containing protein.	Replication factor C (activator 1) 4.	0.619
ENSSPAP00000028301	RFC4	ENSSPAP00000028301	ENSSPAP00000000536	Telo_bind domain-containing protein.	Replication factor C subunit 4.	0.619
ENSSPAP00000028301	acd	ENSSPAP00000028301	ENSSPAP00000022047	Telo_bind domain-containing protein.	Uncharacterized protein.	0.983
ENSSPAP00000028301	dkc1	ENSSPAP00000028301	ENSSPAP00000003556	Telo_bind domain-containing protein.	Dyskeratosis congenita 1, dyskerin.	0.706
ENSSPAP00000028301	rfc2	ENSSPAP00000028301	ENSSPAP00000005522	Telo_bind domain-containing protein.	Replication factor C (activator 1) 2.	0.644
ENSSPAP00000028301	rfc3	ENSSPAP00000028301	ENSSPAP00000015957	Telo_bind domain-containing protein.	Replication factor C (activator 1) 3.	0.693
ENSSPAP00000028301	rfc5	ENSSPAP00000028301	ENSSPAP00000021139	Telo_bind domain-containing protein.	Replication factor C (activator 1) 5.	0.644
ENSSPAP00000028301	wrap53	ENSSPAP00000028301	ENSSPAP00000000715	Telo_bind domain-containing protein.	WD repeat containing, antisense to TP53.	0.686
GREM1	grem1	ENSSPAP00000026047	ENSSPAP00000021049	Gremlin; Belongs to the DAN family.	Gremlin 1a, DAN family BMP antagonist.	0.899
LOC103355474	ENSSPAP00000004083	ENSSPAP00000000463	ENSSPAP00000004083	Replication factor C (activator 1) 4.	Telo_bind domain-containing protein.	0.619