(13 nodes) Positive regulation of stem cell proliferation network (Stegastes partitus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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Predicted Interactions

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Your Input:
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (827 aa)
	sirt6	Sirtuin 6. (349 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1045 aa)
	LOC103356681	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
	ENSSPAP00000007333	Uncharacterized protein. (69 aa)
	atxn1l	Ataxin 1-like. (835 aa)
	LOC103362742	Uncharacterized protein. (120 aa)
	ENSSPAP00000007942	Uncharacterized protein. (176 aa)
	ENSSPAP00000011206	High mobility group AT-hook 2. (108 aa)
	pdcd2	Programmed cell death 2. (366 aa)
	ENSSPAP00000031321	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family. (305 aa)
	LOC103373263	Transforming growth factor beta; Belongs to the TGF-beta family. (384 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
kdm1a	sirt6	ENSSPAP00000022928	ENSSPAP00000004471	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Sirtuin 6.	0.552
sirt6	kdm1a	ENSSPAP00000004471	ENSSPAP00000022928	Sirtuin 6.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.552