(52 nodes) Negative regulation of response to DNA damage stimulus network (Stegastes partitus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSPAP00000019958	Uncharacterized protein. (330 aa)
	LOC103361571	Clusterin; Belongs to the clusterin family. (494 aa)
	ENSSPAP00000000944	G_PROTEIN_RECEP_F1_2 domain-containing protein. (349 aa)
	LOC103371103	Uncharacterized protein. (615 aa)
	rmi2	RecQ mediated genome instability 2. (145 aa)
	fbh1	F-box DNA helicase 1. (1078 aa)
	parpbp	PARP1 binding protein. (548 aa)
	ppp1r10	Protein phosphatase 1, regulatory subunit 10. (810 aa)
	marchf7	Membrane-associated ring finger (C3HC4) 7. (833 aa)
	LOC103362742	Uncharacterized protein. (120 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (695 aa)
	ackr3	Atypical chemokine receptor 3a; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	otub1	Ubiquitin thioesterase. (280 aa)
	ENSSPAP00000010173	FA complementation group B. (724 aa)
	tpt1	Tumor protein, translationally-controlled 1; Belongs to the TCTP family. (195 aa)
	LOC103360719	ATPase family AAA domain containing 5a. (1480 aa)
	ENSSPAP00000011206	High mobility group AT-hook 2. (108 aa)
	bcl2l12	Si:ch73-248e21.1. (359 aa)
	radx	RPA1 related single stranded DNA binding protein. (838 aa)
	ENSSPAP00000013907	TP53 regulated inhibitor of apoptosis 1. (86 aa)
	atad5	ATPase family AAA domain containing 5b. (892 aa)
	ogg1	8-oxoguanine DNA glycosylase. (414 aa)
	recql5	RecQ helicase-like 5. (1018 aa)
	clul1	Clusterin; Belongs to the clusterin family. (449 aa)
	trip12	Thyroid hormone receptor interactor 12. (2024 aa)
	OTUB2	OTU deubiquitinase, ubiquitin aldehyde binding 2. (229 aa)
	xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1. (578 aa)
	cdkn2d	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
	LOC103374810	YJU2 splicing factor homolog. (343 aa)
	smchd1	Structural maintenance of chromosomes flexible hinge domain containing 1. (1866 aa)
	LOC103373663	Zgc:101664. (250 aa)
	ercc4	Excision repair cross-complementation group 4. (899 aa)
	ubr5	Ubiquitin protein ligase E3 component n-recognin 5. (2529 aa)
	LOC103354691	Proteasome 26S subunit, non-ATPase 10. (227 aa)
	clu	Clusterin; Belongs to the clusterin family. (461 aa)
	ENSSPAP00000021362	Ring finger protein 169. (548 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (827 aa)
	ENSSPAP00000023365	Uncharacterized protein. (201 aa)
	ddias	Rep_fac-A_C domain-containing protein. (829 aa)
	LOC103373787	Uncharacterized protein. (311 aa)
	tmem161a	Transmembrane protein 161A. (496 aa)
	rif1	Replication timing regulatory factor 1. (1483 aa)
	thoc1	THO complex 1. (643 aa)
	usp47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1383 aa)
	LOC103372601	Uncharacterized protein. (182 aa)
	trim32	Tripartite motif containing 32. (685 aa)
	ercc1	Excision repair cross-complementation group 1. (361 aa)
	snai2	Snail family zinc finger 2. (260 aa)
	LOC103364319	Excision repair cross-complementation group 6. (1449 aa)
	shld2	Si:ch211-134m17.9. (586 aa)
	tp53bp1	Tumor protein p53 binding protein, 1. (1561 aa)
	ENSSPAP00000030409	Uncharacterized protein. (174 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000010173	ercc1	ENSSPAP00000010173	ENSSPAP00000028788	FA complementation group B.	Excision repair cross-complementation group 1.	0.987
ENSSPAP00000010173	ercc4	ENSSPAP00000010173	ENSSPAP00000019941	FA complementation group B.	Excision repair cross-complementation group 4.	0.982
ENSSPAP00000021362	ENSSPAP00000030409	ENSSPAP00000021362	ENSSPAP00000030409	Ring finger protein 169.	Uncharacterized protein.	0.680
ENSSPAP00000021362	rif1	ENSSPAP00000021362	ENSSPAP00000024338	Ring finger protein 169.	Replication timing regulatory factor 1.	0.402
ENSSPAP00000021362	tp53bp1	ENSSPAP00000021362	ENSSPAP00000030210	Ring finger protein 169.	Tumor protein p53 binding protein, 1.	0.906
ENSSPAP00000021362	trip12	ENSSPAP00000021362	ENSSPAP00000015155	Ring finger protein 169.	Thyroid hormone receptor interactor 12.	0.718
ENSSPAP00000023365	LOC103364319	ENSSPAP00000023365	ENSSPAP00000029616	Uncharacterized protein.	Excision repair cross-complementation group 6.	0.409
ENSSPAP00000023365	parpbp	ENSSPAP00000023365	ENSSPAP00000004783	Uncharacterized protein.	PARP1 binding protein.	0.408
ENSSPAP00000030409	ENSSPAP00000021362	ENSSPAP00000030409	ENSSPAP00000021362	Uncharacterized protein.	Ring finger protein 169.	0.680
ENSSPAP00000030409	LOC103360719	ENSSPAP00000030409	ENSSPAP00000010801	Uncharacterized protein.	ATPase family AAA domain containing 5a.	0.615
ENSSPAP00000030409	LOC103364319	ENSSPAP00000030409	ENSSPAP00000029616	Uncharacterized protein.	Excision repair cross-complementation group 6.	0.415
ENSSPAP00000030409	atad5	ENSSPAP00000030409	ENSSPAP00000014373	Uncharacterized protein.	ATPase family AAA domain containing 5b.	0.615
ENSSPAP00000030409	ercc1	ENSSPAP00000030409	ENSSPAP00000028788	Uncharacterized protein.	Excision repair cross-complementation group 1.	0.510
ENSSPAP00000030409	ercc4	ENSSPAP00000030409	ENSSPAP00000019941	Uncharacterized protein.	Excision repair cross-complementation group 4.	0.733
ENSSPAP00000030409	fbh1	ENSSPAP00000030409	ENSSPAP00000002981	Uncharacterized protein.	F-box DNA helicase 1.	0.467
ENSSPAP00000030409	recql5	ENSSPAP00000030409	ENSSPAP00000014700	Uncharacterized protein.	RecQ helicase-like 5.	0.786
ENSSPAP00000030409	sirt1	ENSSPAP00000030409	ENSSPAP00000008507	Uncharacterized protein.	Deacetylase sirtuin-type domain-containing protein.	0.547
ENSSPAP00000030409	tp53bp1	ENSSPAP00000030409	ENSSPAP00000030210	Uncharacterized protein.	Tumor protein p53 binding protein, 1.	0.994
ENSSPAP00000030409	ubr5	ENSSPAP00000030409	ENSSPAP00000020163	Uncharacterized protein.	Ubiquitin protein ligase E3 component n-recognin 5.	0.477
LOC103360719	ENSSPAP00000030409	ENSSPAP00000010801	ENSSPAP00000030409	ATPase family AAA domain containing 5a.	Uncharacterized protein.	0.615