(26 nodes) Regulation of double-strand break repair via nonhomologous end joining network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103367323	SET domain-containing protein. (2079 aa)
	LOC103364319	Excision repair cross-complementation group 6. (1449 aa)
	ENSSPAP00000028301	Telo_bind domain-containing protein. (326 aa)
	LOC103355430	SET domain and mariner transposase fusion gene. (296 aa)
	LOC103364718	Si:ch73-78o10.1. (107 aa)
	rif1	Replication timing regulatory factor 1. (1483 aa)
	LOC103354764	Uncharacterized protein. (495 aa)
	LOC103369821	SAP domain-containing protein. (460 aa)
	kmt5b	Lysine methyltransferase 5B. (867 aa)
	ENSSPAP00000019958	Uncharacterized protein. (330 aa)
	LOC103373663	Zgc:101664. (250 aa)
	pnkp	Polynucleotide kinase 3'-phosphatase. (607 aa)
	smchd1	Structural maintenance of chromosomes flexible hinge domain containing 1. (1866 aa)
	LOC103358517	Si:dkey-3h3.3. (435 aa)
	prkdc	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3883 aa)
	ENSSPAP00000011206	High mobility group AT-hook 2. (108 aa)
	LOC103368342	Zgc:66440. (351 aa)
	LOC103373487	Nuclear receptor binding SET domain protein 2. (1226 aa)
	sirt7	Sirtuin 7. (407 aa)
	parp3	Poly [ADP-ribose] polymerase. (529 aa)
	LOC103362742	Uncharacterized protein. (120 aa)
	fh	Fumarate hydratase. (499 aa)
	ENSSPAP00000004083	Telo_bind domain-containing protein. (212 aa)
	LOC103358260	RING-type domain-containing protein. (200 aa)
	ENSSPAP00000001358	RING-type domain-containing protein. (218 aa)
	wrap53	WD repeat containing, antisense to TP53. (488 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000004083	wrap53	ENSSPAP00000004083	ENSSPAP00000000715	Telo_bind domain-containing protein.	WD repeat containing, antisense to TP53.	0.686
ENSSPAP00000028301	wrap53	ENSSPAP00000028301	ENSSPAP00000000715	Telo_bind domain-containing protein.	WD repeat containing, antisense to TP53.	0.686
LOC103354764	LOC103355430	ENSSPAP00000023835	ENSSPAP00000027819	Uncharacterized protein.	SET domain and mariner transposase fusion gene.	0.666
LOC103354764	LOC103367323	ENSSPAP00000023835	ENSSPAP00000009720	Uncharacterized protein.	SET domain-containing protein.	0.588
LOC103354764	kmt5b	ENSSPAP00000023835	ENSSPAP00000021136	Uncharacterized protein.	Lysine methyltransferase 5B.	0.616
LOC103354764	prkdc	ENSSPAP00000023835	ENSSPAP00000013021	Uncharacterized protein.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.711
LOC103354764	rif1	ENSSPAP00000023835	ENSSPAP00000024338	Uncharacterized protein.	Replication timing regulatory factor 1.	0.645
LOC103354764	sirt7	ENSSPAP00000023835	ENSSPAP00000010478	Uncharacterized protein.	Sirtuin 7.	0.464
LOC103355430	LOC103354764	ENSSPAP00000027819	ENSSPAP00000023835	SET domain and mariner transposase fusion gene.	Uncharacterized protein.	0.666
LOC103355430	LOC103364319	ENSSPAP00000027819	ENSSPAP00000029616	SET domain and mariner transposase fusion gene.	Excision repair cross-complementation group 6.	0.528
LOC103355430	LOC103367323	ENSSPAP00000027819	ENSSPAP00000009720	SET domain and mariner transposase fusion gene.	SET domain-containing protein.	0.832
LOC103355430	LOC103373487	ENSSPAP00000027819	ENSSPAP00000010702	SET domain and mariner transposase fusion gene.	Nuclear receptor binding SET domain protein 2.	0.666
LOC103355430	kmt5b	ENSSPAP00000027819	ENSSPAP00000021136	SET domain and mariner transposase fusion gene.	Lysine methyltransferase 5B.	0.838
LOC103355430	prkdc	ENSSPAP00000027819	ENSSPAP00000013021	SET domain and mariner transposase fusion gene.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.462
LOC103355430	sirt7	ENSSPAP00000027819	ENSSPAP00000010478	SET domain and mariner transposase fusion gene.	Sirtuin 7.	0.464
LOC103364319	LOC103355430	ENSSPAP00000029616	ENSSPAP00000027819	Excision repair cross-complementation group 6.	SET domain and mariner transposase fusion gene.	0.528
LOC103364319	LOC103369821	ENSSPAP00000029616	ENSSPAP00000022852	Excision repair cross-complementation group 6.	SAP domain-containing protein.	0.781
LOC103364319	parp3	ENSSPAP00000029616	ENSSPAP00000009535	Excision repair cross-complementation group 6.	Poly [ADP-ribose] polymerase.	0.518
LOC103364319	rif1	ENSSPAP00000029616	ENSSPAP00000024338	Excision repair cross-complementation group 6.	Replication timing regulatory factor 1.	0.418
LOC103367323	LOC103354764	ENSSPAP00000009720	ENSSPAP00000023835	SET domain-containing protein.	Uncharacterized protein.	0.588