72 items (Stegastes partitus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103359525	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1686 aa)
	TLR2	Toll like receptor 2; Belongs to the Toll-like receptor family. (794 aa)
	epn2	Epsin 2. (616 aa)
	srgap2	SLIT-ROBO Rho GTPase activating protein 2. (746 aa)
	ENSSPAP00000014896	Uncharacterized protein. (217 aa)
	LOC103355770	Zgc:162171. (247 aa)
	ENSSPAP00000014376	Uncharacterized protein. (199 aa)
	LOC103375967	RAB38c, member of RAS oncogene family. (222 aa)
	LOC103373033	TIR domain-containing protein. (817 aa)
	rab23	RAB23, member RAS oncogene family. (235 aa)
	ENSSPAP00000012938	RAB9B, member RAS oncogene family. (219 aa)
	ap2a2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (956 aa)
	ocrl	OCRL inositol polyphosphate-5-phosphatase. (958 aa)
	ENSSPAP00000012753	Uncharacterized protein. (79 aa)
	LOC103375269	Coronin; Belongs to the WD repeat coronin family. (509 aa)
	LOC103371870	PID domain-containing protein. (161 aa)
	LOC103363555	TIR domain-containing protein; Belongs to the Toll-like receptor family. (827 aa)
	rab35	RAB35, member RAS oncogene family b. (201 aa)
	tlr1	Toll-like receptor 1. (801 aa)
	tlr7	Toll-like receptor 7; Belongs to the Toll-like receptor family. (1053 aa)
	TLR8	Toll like receptor 8. (1027 aa)
	RAB9A	RAB9A, member RAS oncogene family. (206 aa)
	inpp5f	Inositol polyphosphate-5-phosphatase F. (1110 aa)
	LOC103361567	Elastin microfibril interfacer 2a. (1120 aa)
	pip4p1	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (270 aa)
	RAB31	RAB31, member RAS oncogene family. (194 aa)
	ENSSPAP00000002472	Uncharacterized protein. (482 aa)
	MPEG1	Macrophage expressed 1. (890 aa)
	ENSSPAP00000002516	Uncharacterized protein. (192 aa)
	unc93b1	Unc-93 homolog B1, TLR signaling regulator. (633 aa)
	coro6	Coronin; Belongs to the WD repeat coronin family. (423 aa)
	LOC103363306	Scavenger receptor class B, member 2c; Belongs to the CD36 family. (481 aa)
	LOC103366651	Uncharacterized protein. (470 aa)
	ENSSPAP00000004961	Amnion associated transmembrane protein. (474 aa)
	LOC103373570	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (956 aa)
	lamp1	Lysosomal associated membrane protein 1a. (415 aa)
	LOC103373450	Uncharacterized protein. (215 aa)
	slc18a3	Solute carrier family 18 member 3a. (515 aa)
	rab20	RAB20, member RAS oncogene family. (232 aa)
	LOC103367270	VPS9 domain-containing protein. (1015 aa)
	LOC103363410	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (247 aa)
	cltc	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1685 aa)
	LOC103363946	Si:dkey-16l2.16. (209 aa)
	LOC103354488	RAB38b, member of RAS oncogene family. (218 aa)
	ENSSPAP00000008411	Si:dkey-71h2.2. (178 aa)
	LOC103352880	Lysosomal associated membrane protein 1b. (252 aa)
	lyst	Lysosomal trafficking regulator. (3690 aa)
	LOC103375790	Scavenger receptor class B, member 2a; Belongs to the CD36 family. (530 aa)
	LOC103367326	Coronin; Belongs to the WD repeat coronin family. (456 aa)
	lmbrd1	LMBR1 domain containing 1. (538 aa)
	ofd1	OFD1 centriole and centriolar satellite protein. (1066 aa)
	rab14	RAB14, member RAS oncogene family. (215 aa)
	SLC18A3	Solute carrier family 18 member A3. (523 aa)
	appl2	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (664 aa)
	LOC103367651	Epsin 1. (664 aa)
	rab22a	RAB22A, member RAS oncogene family. (194 aa)
	LOC103365899	Si:dkey-13a21.4. (194 aa)
	RAB38	RAB38, member RAS oncogene family. (212 aa)
	tlr3	Toll-like receptor 3. (910 aa)
	LOC103364208	RAB32b, member RAS oncogene family. (219 aa)
	LOC103362575	Toll-like receptor 18. (922 aa)
	mib1	Mindbomb E3 ubiquitin protein ligase 1. (1020 aa)
	appl1	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (708 aa)
	ENSSPAP00000021245	Uncharacterized protein. (88 aa)
	LOC103353121	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1684 aa)
	ap2s1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	LOC103375504	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (275 aa)
	pip4p2	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (256 aa)
	vamp4	Vesicle-associated membrane protein 4. (140 aa)
	LOC103361359	Si:dkey-19b23.8. (226 aa)
	snx3	Sorting nexin 3. (163 aa)
	inpp5b	Inositol polyphosphate-5-phosphatase B. (858 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000002516	ENSSPAP00000012753	ENSSPAP00000002516	ENSSPAP00000012753	Uncharacterized protein.	Uncharacterized protein.	0.487
ENSSPAP00000002516	LOC103366651	ENSSPAP00000002516	ENSSPAP00000004437	Uncharacterized protein.	Uncharacterized protein.	0.446
ENSSPAP00000002516	LOC103373450	ENSSPAP00000002516	ENSSPAP00000006663	Uncharacterized protein.	Uncharacterized protein.	0.434
ENSSPAP00000002516	appl1	ENSSPAP00000002516	ENSSPAP00000023278	Uncharacterized protein.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	0.538
ENSSPAP00000002516	appl2	ENSSPAP00000002516	ENSSPAP00000029332	Uncharacterized protein.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	0.538
ENSSPAP00000002516	rab14	ENSSPAP00000002516	ENSSPAP00000030546	Uncharacterized protein.	RAB14, member RAS oncogene family.	0.434
ENSSPAP00000002516	rab35	ENSSPAP00000002516	ENSSPAP00000011037	Uncharacterized protein.	RAB35, member RAS oncogene family b.	0.866
ENSSPAP00000008411	LOC103353121	ENSSPAP00000008411	ENSSPAP00000021176	Si:dkey-71h2.2.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.541
ENSSPAP00000008411	LOC103359525	ENSSPAP00000008411	ENSSPAP00000010088	Si:dkey-71h2.2.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.541
ENSSPAP00000008411	LOC103373570	ENSSPAP00000008411	ENSSPAP00000006449	Si:dkey-71h2.2.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.550
ENSSPAP00000008411	ap2s1	ENSSPAP00000008411	ENSSPAP00000021120	Si:dkey-71h2.2.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.451
ENSSPAP00000008411	appl1	ENSSPAP00000008411	ENSSPAP00000023278	Si:dkey-71h2.2.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	0.830
ENSSPAP00000008411	appl2	ENSSPAP00000008411	ENSSPAP00000029332	Si:dkey-71h2.2.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	0.830
ENSSPAP00000008411	cltc	ENSSPAP00000008411	ENSSPAP00000008062	Si:dkey-71h2.2.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.541
ENSSPAP00000012753	ENSSPAP00000002516	ENSSPAP00000012753	ENSSPAP00000002516	Uncharacterized protein.	Uncharacterized protein.	0.487
ENSSPAP00000012753	LOC103363946	ENSSPAP00000012753	ENSSPAP00000008261	Uncharacterized protein.	Si:dkey-16l2.16.	0.487
ENSSPAP00000012753	appl1	ENSSPAP00000012753	ENSSPAP00000023278	Uncharacterized protein.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	0.719
ENSSPAP00000012753	appl2	ENSSPAP00000012753	ENSSPAP00000029332	Uncharacterized protein.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	0.719
ENSSPAP00000012753	rab35	ENSSPAP00000012753	ENSSPAP00000011037	Uncharacterized protein.	RAB35, member RAS oncogene family b.	0.487
ENSSPAP00000012938	ENSSPAP00000014896	ENSSPAP00000012938	ENSSPAP00000014896	RAB9B, member RAS oncogene family.	Uncharacterized protein.	0.899