(32 nodes) HSP20-like chaperone network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSPAP00000007597	Tudor domain containing 12. (1056 aa)
	ENSSPAP00000009217	Uncharacterized protein. (48 aa)
	LOC103355652	Cytochrome b5 reductase 4. (572 aa)
	cryab	Crystallin, alpha B, a; Belongs to the small heat shock protein (HSP20) family. (162 aa)
	dnaaf4	Dynein axonemal assembly factor 4. (397 aa)
	LOC103368333	Prostaglandin E synthase 3a (cytosolic). (159 aa)
	LOC103354648	Heat shock protein, alpha-crystallin-related, b11; Belongs to the small heat shock protein (HSP20) family. (192 aa)
	nudcd2	NudC domain containing 2. (157 aa)
	ENSSPAP00000017396	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (206 aa)
	hspb6	Heat shock protein, alpha-crystallin-related, b6; Belongs to the small heat shock protein (HSP20) family. (145 aa)
	cryaa	Crystallin, alpha A; Belongs to the small heat shock protein (HSP20) family. (176 aa)
	hspb8	Heat shock protein b8; Belongs to the small heat shock protein (HSP20) family. (223 aa)
	ptges3	Prostaglandin E synthase 3b (cytosolic). (159 aa)
	ENSSPAP00000021678	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (206 aa)
	HACD3	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (355 aa)
	LOC103364169	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (226 aa)
	LOC103363690	Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family. (202 aa)
	LOC103367014	Prostaglandin E synthase 3 like. (158 aa)
	hacd3	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (357 aa)
	LOC103363025	Zgc:92429. (374 aa)
	sugt1	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (323 aa)
	LOC103359448	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (139 aa)
	ENSSPAP00000003426	CS domain-containing protein. (126 aa)
	nudc	NudC nuclear distribution protein. (340 aa)
	cacybp	Calcyclin binding protein. (227 aa)
	usp19	Ubiquitin specific peptidase 19. (1510 aa)
	ENSSPAP00000030410	Uncharacterized protein. (204 aa)
	LOC103360654	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (204 aa)
	hspb7	Heat shock protein family, member 7 (cardiovascular); Belongs to the small heat shock protein (HSP20) family. (156 aa)
	nudcd3	NudC domain containing 3. (363 aa)
	LOC103362636	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (110 aa)
	chordc1	Cysteine and histidine-rich domain (CHORD) containing 1b. (338 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000003426	nudc	ENSSPAP00000003426	ENSSPAP00000001292	CS domain-containing protein.	NudC nuclear distribution protein.	0.415
ENSSPAP00000003426	nudcd2	ENSSPAP00000003426	ENSSPAP00000016176	CS domain-containing protein.	NudC domain containing 2.	0.462
ENSSPAP00000017396	LOC103360654	ENSSPAP00000017396	ENSSPAP00000008488	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.696
ENSSPAP00000017396	LOC103363690	ENSSPAP00000017396	ENSSPAP00000023544	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family.	0.696
ENSSPAP00000017396	cryaa	ENSSPAP00000017396	ENSSPAP00000019140	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	Crystallin, alpha A; Belongs to the small heat shock protein (HSP20) family.	0.719
ENSSPAP00000017396	cryab	ENSSPAP00000017396	ENSSPAP00000010293	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	Crystallin, alpha B, a; Belongs to the small heat shock protein (HSP20) family.	0.718
ENSSPAP00000017396	hspb6	ENSSPAP00000017396	ENSSPAP00000019117	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein, alpha-crystallin-related, b6; Belongs to the small heat shock protein (HSP20) family.	0.702
ENSSPAP00000021678	LOC103360654	ENSSPAP00000021678	ENSSPAP00000008488	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.821
ENSSPAP00000030410	LOC103360654	ENSSPAP00000030410	ENSSPAP00000008488	Uncharacterized protein.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.696
ENSSPAP00000030410	LOC103363690	ENSSPAP00000030410	ENSSPAP00000023544	Uncharacterized protein.	Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family.	0.696
ENSSPAP00000030410	cryaa	ENSSPAP00000030410	ENSSPAP00000019140	Uncharacterized protein.	Crystallin, alpha A; Belongs to the small heat shock protein (HSP20) family.	0.719
ENSSPAP00000030410	cryab	ENSSPAP00000030410	ENSSPAP00000010293	Uncharacterized protein.	Crystallin, alpha B, a; Belongs to the small heat shock protein (HSP20) family.	0.718
ENSSPAP00000030410	hspb6	ENSSPAP00000030410	ENSSPAP00000019117	Uncharacterized protein.	Heat shock protein, alpha-crystallin-related, b6; Belongs to the small heat shock protein (HSP20) family.	0.702
HACD3	LOC103355652	ENSSPAP00000022896	ENSSPAP00000009962	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Cytochrome b5 reductase 4.	0.489
HACD3	hacd3	ENSSPAP00000022896	ENSSPAP00000024819	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.899
LOC103355652	HACD3	ENSSPAP00000009962	ENSSPAP00000022896	Cytochrome b5 reductase 4.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.489
LOC103355652	hacd3	ENSSPAP00000009962	ENSSPAP00000024819	Cytochrome b5 reductase 4.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.489
LOC103360654	ENSSPAP00000017396	ENSSPAP00000008488	ENSSPAP00000017396	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.696
LOC103360654	ENSSPAP00000021678	ENSSPAP00000008488	ENSSPAP00000021678	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.821
LOC103360654	ENSSPAP00000030410	ENSSPAP00000008488	ENSSPAP00000030410	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	Uncharacterized protein.	0.696