55 items (Stegastes partitus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tpr	Translocated promoter region b, nuclear basket protein. (2164 aa)
	LOC103366963	Small ubiquitin-related modifier. (101 aa)
	nup43	Nucleoporin 43. (372 aa)
	ube2i	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	aaas	Achalasia, adrenocortical insufficiency, alacrimia. (519 aa)
	LOC103366028	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (604 aa)
	pom121c	POM121 transmembrane nucleoporin. (1184 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	nup160	Nucleoporin 160. (1123 aa)
	nup42	Nucleoporin 42. (482 aa)
	LOC103367279	Aurora kinase B; Belongs to the protein kinase superfamily. (332 aa)
	rangap1	RAN GTPase activating protein 1a. (593 aa)
	nup88	Nucleoporin 88. (719 aa)
	nup35	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (298 aa)
	ENSSPAP00000025164	Rad60-SLD domain-containing protein. (149 aa)
	pias1	Protein inhibitor of activated STAT, 1a. (698 aa)
	LOC103353782	Ubiquitin-like domain-containing protein. (131 aa)
	rae1	Ribonucleic acid export 1. (368 aa)
	LOC103365891	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (755 aa)
	LOC103354886	Small ubiquitin-related modifier. (96 aa)
	nup210	Nucleoporin 210. (1857 aa)
	nup58	Nucleoporin 58. (599 aa)
	nup37	Nucleoporin 37. (323 aa)
	NUP54	Nucleoporin 54. (567 aa)
	top2a	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1569 aa)
	LOC103372741	Protein inhibitor of activated STAT, 1b. (544 aa)
	LOC103371565	Ran GTPase activating protein 1b. (577 aa)
	nup155	Nucleoporin 155. (1367 aa)
	nup188	Nucleoporin 188. (1713 aa)
	LOC103368977	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (794 aa)
	top2b	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1611 aa)
	LOC103370131	Translocated promoter region a, nuclear basket protein. (1853 aa)
	NUP62	Nucleoporin 62. (573 aa)
	ndc1	NDC1 transmembrane nucleoporin. (640 aa)
	nup205	Nucleoporin 205. (1993 aa)
	LOC103368463	Baculoviral IAP repeat containing 5b. (147 aa)
	nup93	Nucleoporin 93. (671 aa)
	LOC103353462	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (597 aa)
	ranbp2	RAN binding protein 2. (3063 aa)
	LOC103371831	Potassium channel tetramerization domain containing 2. (277 aa)
	LOC103370190	Ubiquitin-like domain-containing protein. (112 aa)
	nup133	Nucleoporin 133. (1137 aa)
	cdca8	Cell division cycle associated 8. (278 aa)
	LOC103358548	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	LOC103374293	Baculoviral IAP repeat containing 5a. (225 aa)
	nup50	Nucleoporin 50. (447 aa)
	seh1l	SEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (415 aa)
	nup98	Nucleoporin 98. (1839 aa)
	nup107	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (858 aa)
	incenp	Uncharacterized protein. (834 aa)
	nup85	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (652 aa)
	sumo2	Rad60-SLD domain-containing protein. (71 aa)
	nup153	Nucleoporin 153. (1528 aa)
	pias4	Protein inhibitor of activated STAT, 4a. (507 aa)
	NUP214	Nucleoporin 214. (1979 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000025164	LOC103353462	ENSSPAP00000025164	ENSSPAP00000009984	Rad60-SLD domain-containing protein.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	0.703
ENSSPAP00000025164	LOC103358548	ENSSPAP00000025164	ENSSPAP00000017820	Rad60-SLD domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.867
ENSSPAP00000025164	LOC103365891	ENSSPAP00000025164	ENSSPAP00000028097	Rad60-SLD domain-containing protein.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	0.703
ENSSPAP00000025164	LOC103366028	ENSSPAP00000025164	ENSSPAP00000001241	Rad60-SLD domain-containing protein.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	0.703
ENSSPAP00000025164	LOC103367279	ENSSPAP00000025164	ENSSPAP00000003712	Rad60-SLD domain-containing protein.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.560
ENSSPAP00000025164	LOC103368977	ENSSPAP00000025164	ENSSPAP00000007535	Rad60-SLD domain-containing protein.	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family.	0.649
ENSSPAP00000025164	LOC103370131	ENSSPAP00000025164	ENSSPAP00000008697	Rad60-SLD domain-containing protein.	Translocated promoter region a, nuclear basket protein.	0.636
ENSSPAP00000025164	LOC103371565	ENSSPAP00000025164	ENSSPAP00000030539	Rad60-SLD domain-containing protein.	Ran GTPase activating protein 1b.	0.840
ENSSPAP00000025164	LOC103371831	ENSSPAP00000025164	ENSSPAP00000010517	Rad60-SLD domain-containing protein.	Potassium channel tetramerization domain containing 2.	0.851
ENSSPAP00000025164	LOC103372741	ENSSPAP00000025164	ENSSPAP00000030747	Rad60-SLD domain-containing protein.	Protein inhibitor of activated STAT, 1b.	0.768
ENSSPAP00000025164	NUP214	ENSSPAP00000025164	ENSSPAP00000004542	Rad60-SLD domain-containing protein.	Nucleoporin 214.	0.619
ENSSPAP00000025164	NUP54	ENSSPAP00000025164	ENSSPAP00000005263	Rad60-SLD domain-containing protein.	Nucleoporin 54.	0.560
ENSSPAP00000025164	NUP62	ENSSPAP00000025164	ENSSPAP00000008713	Rad60-SLD domain-containing protein.	Nucleoporin 62.	0.576
ENSSPAP00000025164	cdca8	ENSSPAP00000025164	ENSSPAP00000016779	Rad60-SLD domain-containing protein.	Cell division cycle associated 8.	0.483
ENSSPAP00000025164	incenp	ENSSPAP00000025164	ENSSPAP00000019208	Rad60-SLD domain-containing protein.	Uncharacterized protein.	0.533
ENSSPAP00000025164	ndc1	ENSSPAP00000025164	ENSSPAP00000008811	Rad60-SLD domain-containing protein.	NDC1 transmembrane nucleoporin.	0.516
ENSSPAP00000025164	nup107	ENSSPAP00000025164	ENSSPAP00000019097	Rad60-SLD domain-containing protein.	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	0.686
ENSSPAP00000025164	nup133	ENSSPAP00000025164	ENSSPAP00000014180	Rad60-SLD domain-containing protein.	Nucleoporin 133.	0.672
ENSSPAP00000025164	nup153	ENSSPAP00000025164	ENSSPAP00000019808	Rad60-SLD domain-containing protein.	Nucleoporin 153.	0.777
ENSSPAP00000025164	nup155	ENSSPAP00000025164	ENSSPAP00000006429	Rad60-SLD domain-containing protein.	Nucleoporin 155.	0.601