STRINGSTRING
insr insr LOC103355494 LOC103355494 LOC103358235 LOC103358235 frs2 frs2 LOC103356033 LOC103356033 LOC103368870 LOC103368870 LOC103367182 LOC103367182 LOC103372228 LOC103372228 LOC103358412 LOC103358412 ENSSPAP00000002911 ENSSPAP00000002911 ENSSPAP00000002926 ENSSPAP00000002926 LOC103373900 LOC103373900 LOC103361681 LOC103361681 LOC103359773 LOC103359773 gab1 gab1 LOC103353330 LOC103353330 LOC103363304 LOC103363304 ENSSPAP00000004222 ENSSPAP00000004222 LOC103367716 LOC103367716 LOC103363329 LOC103363329 ENSSPAP00000013101 ENSSPAP00000013101 ENSSPAP00000013165 ENSSPAP00000013165 pde3b pde3b ENSSPAP00000013326 ENSSPAP00000013326 atp6v0a2 atp6v0a2 LOC103375129 LOC103375129 LOC103371225 LOC103371225 LOC103363938 LOC103363938 pik3ca pik3ca NRDC NRDC fgf2 fgf2 LOC103374774 LOC103374774 LOC103367412 LOC103367412 kl kl fgf1 fgf1 pik3cb pik3cb LOC103359141 LOC103359141 fgf16 fgf16 LOC103369585 LOC103369585 LOC103369164 LOC103369164 ENSSPAP00000001054 ENSSPAP00000001054 LOC103356037 LOC103356037 LOC103368826 LOC103368826 atp6v1d atp6v1d ENSSPAP00000021647 ENSSPAP00000021647 LOC103376450 LOC103376450 pdpk1 pdpk1 atp6v1h atp6v1h LOC103359300 LOC103359300 LOC103374382 LOC103374382 shc1 shc1 LOC103369321 LOC103369321 ENSSPAP00000024770 ENSSPAP00000024770 fgf22 fgf22 lctl lctl ptprf ptprf akt2 akt2 LOC103374338 LOC103374338 LOC103353638 LOC103353638 atp6v1a atp6v1a atp6v1c1 atp6v1c1 LOC103376360 LOC103376360 LOC103364653 LOC103364653 LOC103354683 LOC103354683 ENSSPAP00000019912 ENSSPAP00000019912 LOC103362437 LOC103362437 atp6v1f atp6v1f LOC103353067 LOC103353067 ptpn1 ptpn1 ENSSPAP00000018486 ENSSPAP00000018486 fgf8 fgf8 LOC103356681 LOC103356681 grb2 grb2 ide ide LOC103362820 LOC103362820 FGF6 FGF6 ENSSPAP00000007333 ENSSPAP00000007333 INSR INSR fgfr2 fgfr2 gab2 gab2 LOC103365022 LOC103365022 klb klb fgf13 fgf13 LOC103365648 LOC103365648 ENSSPAP00000011287 ENSSPAP00000011287 atp6v0e1 atp6v0e1 LOC103372997 LOC103372997 ATP6V1B2 ATP6V1B2 fgf10 fgf10 ENSSPAP00000012951 ENSSPAP00000012951 LOC103369873 LOC103369873 fgf23 fgf23 FGF6-2 FGF6-2 LOC103358108 LOC103358108 fgf7 fgf7 atp6v1c2 atp6v1c2 ENSSPAP00000026412 ENSSPAP00000026412 LOC103376159 LOC103376159 atp6v0b atp6v0b ENSSPAP00000026986 ENSSPAP00000026986 atp6v0a1 atp6v0a1 LOC103365878 LOC103365878 fgfr3 fgfr3 LOC103365332 LOC103365332 atp6ap1 atp6ap1 ENSSPAP00000028255 ENSSPAP00000028255 ENSSPAP00000028307 ENSSPAP00000028307 fgf19 fgf19 fgf4 fgf4 fgf3 fgf3 LOC103372666 LOC103372666
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
insrTyrosine-protein kinase receptor. (1368 aa)
LOC103355494V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (834 aa)
LOC103358235Insulin receptor substrate 2a. (1056 aa)
frs2Fibroblast growth factor receptor substrate 2b. (522 aa)
LOC103356033Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC103368870Lactase-like a; Belongs to the glycosyl hydrolase 1 family. (569 aa)
LOC103367182Consortin_C domain-containing protein. (812 aa)
LOC103372228Insulin receptor substrate 2b. (1123 aa)
LOC103358412V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (352 aa)
ENSSPAP00000002911Zgc:158659; Belongs to the PI3/PI4-kinase family. (508 aa)
ENSSPAP00000002926PI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (318 aa)
LOC103373900Consortin_C domain-containing protein. (363 aa)
LOC103361681ATPase H+ transporting accessory protein 1b. (469 aa)
LOC103359773Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
gab1GRB2-associated binding protein 1. (787 aa)
LOC103353330Uncharacterized protein. (623 aa)
LOC103363304Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (248 aa)
ENSSPAP00000004222Uncharacterized protein. (285 aa)
LOC103367716Tribbles pseudokinase 3. (356 aa)
LOC103363329Fibroblast growth factor receptor 4. (945 aa)
ENSSPAP00000013101Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (266 aa)
ENSSPAP00000013165Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (273 aa)
pde3bPhosphodiesterase. (650 aa)
ENSSPAP00000013326Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (550 aa)
atp6v0a2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (849 aa)
LOC103375129V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (153 aa)
LOC103371225Consortin_C domain-containing protein. (775 aa)
LOC103363938Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
NRDCNardilysin b (N-arginine dibasic convertase); Belongs to the peptidase M16 family. (1036 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LOC103374774Tyrosine-protein kinase receptor. (1122 aa)
LOC103367412Growth factor receptor-bound protein 10a. (601 aa)
klKlotho. (995 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (181 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1079 aa)
LOC103359141Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (149 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
LOC103369585Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (51 aa)
LOC103369164V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (152 aa)
ENSSPAP00000001054Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
LOC103356037Lens intrinsic membrane protein 2.1. (173 aa)
LOC103368826V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
atp6v1dATPase H+ transporting V1 subunit D. (248 aa)
ENSSPAP00000021647Uncharacterized protein. (194 aa)
LOC103376450Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (503 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (584 aa)
atp6v1hV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (482 aa)
LOC103359300Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
LOC103374382Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (434 aa)
LOC103369321V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
ENSSPAP00000024770Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
lctlLactase-like b; Belongs to the glycosyl hydrolase 1 family. (570 aa)
ptprfProtein tyrosine phosphatase receptor type Fa. (1910 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (483 aa)
LOC103374338V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
LOC103353638Fibroblast growth factor receptor. (833 aa)
atp6v1aATPase H+ transporting V1 subunit A. (617 aa)
atp6v1c1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (383 aa)
LOC103376360V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
LOC103364653Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (227 aa)
LOC103354683Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (65 aa)
ENSSPAP00000019912Uncharacterized protein. (294 aa)
LOC103362437Lens intrinsic membrane protein 2.3. (173 aa)
atp6v1fV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
LOC103353067Protein tyrosine phosphatase receptor type Fb. (1902 aa)
ptpn1Tyrosine-protein phosphatase non-receptor type. (438 aa)
ENSSPAP00000018486PH domain-containing protein. (356 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
LOC103356681Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
ideInsulin-degrading enzyme; Belongs to the peptidase M16 family. (1014 aa)
LOC103362820ATPase H+ transporting accessory protein 1 like b. (289 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSSPAP00000007333Uncharacterized protein. (69 aa)
INSRInsulin receptor. (669 aa)
fgfr2Fibroblast growth factor receptor. (836 aa)
gab2GRB2-associated binding protein 2. (679 aa)
LOC103365022ATPase H+ transporting V1 subunit E1a. (226 aa)
klbKlotho beta. (1056 aa)
fgf13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
LOC103365648V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (828 aa)
ENSSPAP00000011287ATPase H+ transporting accessory protein 1 like a. (294 aa)
atp6v0e1V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
LOC103372997Fibroblast growth factor receptor. (714 aa)
ATP6V1B2ATPase H+ transporting V1 subunit B2. (174 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
ENSSPAP00000012951Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (533 aa)
LOC103369873Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (78 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (262 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC103358108ATPase H+ transporting V1 subunit E1b. (226 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
atp6v1c2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (401 aa)
ENSSPAP00000026412Uncharacterized protein. (280 aa)
LOC103376159Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
atp6v0bATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (284 aa)
ENSSPAP00000026986Fibroblast growth factor 5; Belongs to the heparin-binding growth factors family. (198 aa)
atp6v0a1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (841 aa)
LOC103365878Nardilysin a (N-arginine dibasic convertase); Belongs to the peptidase M16 family. (1039 aa)
fgfr3Fibroblast growth factor receptor. (862 aa)
LOC103365332Growth factor receptor-bound protein 10b. (629 aa)
atp6ap1ATPase H+ transporting accessory protein 1a. (463 aa)
ENSSPAP00000028255V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (72 aa)
ENSSPAP00000028307V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (138 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (247 aa)
LOC103372666Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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