(58 nodes) Pentose phosphate pathway network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103373891	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (481 aa)
	LOC103365994	Glucose-6-phosphate isomerase; Belongs to the GPI family. (502 aa)
	rbm45	RNA binding motif protein 45. (476 aa)
	ENSSPAP00000008530	Uncharacterized protein. (84 aa)
	glyctk	Glycerate kinase. (519 aa)
	LOC103368244	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
	LOC103352918	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (249 aa)
	IDNK	IDNK gluconokinase. (191 aa)
	ENSSPAP00000010428	RRM domain-containing protein. (131 aa)
	ENSSPAP00000010491	EPS8-like 3a. (523 aa)
	dera	Deoxyribose-phosphate aldolase (putative). (318 aa)
	aldob	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	eps8l1	Eps8 like 1a. (508 aa)
	pgd	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
	prps2	Pribosyltran_N domain-containing protein. (318 aa)
	PRPSAP1	Phosphoribosyl pyrophosphate synthetase associated protein 1. (356 aa)
	LOC103372385	6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (745 aa)
	LOC103373074	Eps8 like 1b. (514 aa)
	prpsap2	Phosphoribosyl pyrophosphate synthetase-associated protein 2. (367 aa)
	prps1	Phosphoribosyl pyrophosphate synthetase 1B. (318 aa)
	LOC103357398	Si:dkey-205h23.2. (436 aa)
	rbks	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (312 aa)
	aldoc	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (412 aa)
	PFKP	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (788 aa)
	LOC103359635	Transketolase a. (628 aa)
	g6pd	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (514 aa)
	LOC103362656	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (377 aa)
	LOC103353278	Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (337 aa)
	celf5	Cugbp, Elav-like family member 5a. (451 aa)
	LOC103354901	Pribosyltran_N domain-containing protein. (397 aa)
	pfkl	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
	pgm2	Phosphoglucomutase 2. (611 aa)
	ENSSPAP00000026885	Uncharacterized protein. (356 aa)
	ENSSPAP00000026857	Uncharacterized protein. (247 aa)
	LOC103363731	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (514 aa)
	wrap73	WD repeat containing, antisense to TP73. (449 aa)
	taldo1	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (338 aa)
	LOC103365291	Cugbp, Elav-like family member 3b. (495 aa)
	EPS8L2	EPS8 like 2. (686 aa)
	celf4	CUGBP, Elav-like family member 4. (427 aa)
	jade1	Jade family PHD finger 1. (927 aa)
	jade3	Jade family PHD finger 3. (784 aa)
	pgls	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (253 aa)
	TKT	Transketolase. (628 aa)
	fbp2	Fructose-1,6-bisphosphatase 2; Belongs to the FBPase class 1 family. (337 aa)
	LOC103353425	Fructose-1,6-bisphosphatase 1a; Belongs to the FBPase class 1 family. (338 aa)
	h6pd	Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase). (791 aa)
	pgm5	Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (567 aa)
	LOC103364420	Uncharacterized protein; Belongs to the phosphohexose mutase family. (564 aa)
	LOC103362814	Transketolase b. (626 aa)
	ENSSPAP00000005870	PTB domain-containing protein. (191 aa)
	eps8	Epidermal growth factor receptor pathway substrate 8a. (728 aa)
	pgm1	Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. (561 aa)
	LOC103356397	Cugbp, Elav-like family member 3a. (433 aa)
	gpi	Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
	rpia	Ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase). (258 aa)
	LOC103376601	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (778 aa)
	ENSSPAP00000001462	Uncharacterized protein. (93 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000001462	ENSSPAP00000005870	ENSSPAP00000001462	ENSSPAP00000005870	Uncharacterized protein.	PTB domain-containing protein.	0.439
ENSSPAP00000001462	ENSSPAP00000008530	ENSSPAP00000001462	ENSSPAP00000008530	Uncharacterized protein.	Uncharacterized protein.	0.713
ENSSPAP00000001462	ENSSPAP00000010491	ENSSPAP00000001462	ENSSPAP00000010491	Uncharacterized protein.	EPS8-like 3a.	0.439
ENSSPAP00000001462	EPS8L2	ENSSPAP00000001462	ENSSPAP00000024328	Uncharacterized protein.	EPS8 like 2.	0.453
ENSSPAP00000001462	LOC103352918	ENSSPAP00000001462	ENSSPAP00000009670	Uncharacterized protein.	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.	0.761
ENSSPAP00000001462	LOC103353278	ENSSPAP00000001462	ENSSPAP00000029952	Uncharacterized protein.	Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family.	0.871
ENSSPAP00000001462	LOC103353425	ENSSPAP00000001462	ENSSPAP00000007752	Uncharacterized protein.	Fructose-1,6-bisphosphatase 1a; Belongs to the FBPase class 1 family.	0.871
ENSSPAP00000001462	LOC103359635	ENSSPAP00000001462	ENSSPAP00000021429	Uncharacterized protein.	Transketolase a.	0.873
ENSSPAP00000001462	LOC103362656	ENSSPAP00000001462	ENSSPAP00000030017	Uncharacterized protein.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.730
ENSSPAP00000001462	LOC103362814	ENSSPAP00000001462	ENSSPAP00000006183	Uncharacterized protein.	Transketolase b.	0.873
ENSSPAP00000001462	LOC103364420	ENSSPAP00000001462	ENSSPAP00000006220	Uncharacterized protein.	Uncharacterized protein; Belongs to the phosphohexose mutase family.	0.499
ENSSPAP00000001462	LOC103365994	ENSSPAP00000001462	ENSSPAP00000031244	Uncharacterized protein.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.948
ENSSPAP00000001462	LOC103373074	ENSSPAP00000001462	ENSSPAP00000015836	Uncharacterized protein.	Eps8 like 1b.	0.452
ENSSPAP00000001462	LOC103373891	ENSSPAP00000001462	ENSSPAP00000000743	Uncharacterized protein.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.730
ENSSPAP00000001462	TKT	ENSSPAP00000001462	ENSSPAP00000008110	Uncharacterized protein.	Transketolase.	0.873
ENSSPAP00000001462	aldob	ENSSPAP00000001462	ENSSPAP00000011499	Uncharacterized protein.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.865
ENSSPAP00000001462	aldoc	ENSSPAP00000001462	ENSSPAP00000018716	Uncharacterized protein.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.730
ENSSPAP00000001462	eps8	ENSSPAP00000001462	ENSSPAP00000005710	Uncharacterized protein.	Epidermal growth factor receptor pathway substrate 8a.	0.453
ENSSPAP00000001462	eps8l1	ENSSPAP00000001462	ENSSPAP00000012633	Uncharacterized protein.	Eps8 like 1a.	0.452
ENSSPAP00000001462	fbp2	ENSSPAP00000001462	ENSSPAP00000007781	Uncharacterized protein.	Fructose-1,6-bisphosphatase 2; Belongs to the FBPase class 1 family.	0.871