(69 nodes) Fructose and mannose metabolism network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103369358	Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 1. (316 aa)
	pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b. (457 aa)
	LOC103373891	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (481 aa)
	ENSSPAP00000001462	Uncharacterized protein. (93 aa)
	fpgt	Fucose-1-phosphate guanylyltransferase. (578 aa)
	tnni3k	TNNI3 interacting kinase. (728 aa)
	fcsk	Fucose kinase. (918 aa)
	LOC103366979	Zgc:101583. (381 aa)
	EEF1AKMT3	EEF1A lysine methyltransferase 3. (223 aa)
	LOC103376601	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (778 aa)
	pfkfb3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3. (526 aa)
	pfkfb1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (463 aa)
	lmcd1	LIM and cysteine-rich domains 1. (356 aa)
	pmm1	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (261 aa)
	pmm2	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (250 aa)
	tpi1	Triosephosphate isomerase. (235 aa)
	LOC103353425	Fructose-1,6-bisphosphatase 1a; Belongs to the FBPase class 1 family. (338 aa)
	fbp2	Fructose-1,6-bisphosphatase 2; Belongs to the FBPase class 1 family. (337 aa)
	mettl21a	Methyltransferase like 21A. (218 aa)
	ENSSPAP00000008530	Uncharacterized protein. (84 aa)
	ENSSPAP00000008691	Uncharacterized protein. (241 aa)
	etfbkmt	Electron transfer flavoprotein subunit beta lysine methyltransferase. (248 aa)
	gmppa	GDP-mannose pyrophosphorylase Ab. (427 aa)
	LOC103368244	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
	trmt1	tRNA (guanine(26)-N(2))-dimethyltransferase. (649 aa)
	khk	Ketohexokinase. (305 aa)
	trmt1l	tRNA methyltransferase 1-like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (677 aa)
	aldob	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	LOC103359076	Uncharacterized protein. (704 aa)
	LOC103369118	Hexokinase 2. (884 aa)
	vcpkmt	Valosin containing protein lysine (K) methyltransferase. (223 aa)
	enosf1	Enolase superfamily member 1. (437 aa)
	LOC103372385	6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (745 aa)
	ENSSPAP00000016231	Phosphotransferase. (282 aa)
	hkdc1	Hexokinase domain containing 1. (892 aa)
	mpi	Mannose phosphate isomerase. (364 aa)
	tkfc	Triokinase/FMN cyclase. (546 aa)
	LOC103356835	Triosephosphate isomerase. (248 aa)
	aldoc	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (412 aa)
	LOC103373149	Hexokinase domain containing 1. (906 aa)
	hk1	Hexokinase 1. (918 aa)
	ENSSPAP00000019558	Phosphotransferase. (476 aa)
	NIPAL2	NIPA like domain containing 2. (365 aa)
	ENSSPAP00000019840	NTP_transferase domain-containing protein. (64 aa)
	PFKP	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (788 aa)
	LOC103365134	Si:ch73-244f7.3. (506 aa)
	LOC103365143	Zgc:92518. (250 aa)
	gmppb	GDP-mannose pyrophosphorylase B. (360 aa)
	LOC103376073	TP53 induced glycolysis regulatory phosphatase a. (269 aa)
	gmds	GDP-mannose 4,6-dehydratase. (363 aa)
	tsta3	Tissue specific transplantation antigen P35B. (326 aa)
	nipa1	NIPA magnesium transporter 1. (335 aa)
	nipa2	NIPA magnesium transporter 2. (388 aa)
	nipal3	NIPA like domain containing 3. (383 aa)
	PFKFB2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a. (521 aa)
	LOC103369357	Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2. (348 aa)
	LOC103369877	NIPA like domain containing 4. (339 aa)
	sord	Sorbitol dehydrogenase. (354 aa)
	tigar	TP53 induced glycolysis regulatory phosphatase b. (263 aa)
	LOC103358721	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b. (474 aa)
	wrap73	WD repeat containing, antisense to TP73. (449 aa)
	LOC103375654	Uncharacterized protein. (272 aa)
	PFKFB4	6PF2K domain-containing protein. (495 aa)
	LOC103361531	6PF2K domain-containing protein. (469 aa)
	pfkl	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
	fuom	Fucose mutarotase. (187 aa)
	LOC103353278	Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (337 aa)
	LOC103362656	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (377 aa)
	mettl23	Methyltransferase like 23. (233 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEF1AKMT3	LOC103353278	ENSSPAP00000002316	ENSSPAP00000029952	EEF1A lysine methyltransferase 3.	Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family.	0.498
EEF1AKMT3	LOC103353425	ENSSPAP00000002316	ENSSPAP00000007752	EEF1A lysine methyltransferase 3.	Fructose-1,6-bisphosphatase 1a; Belongs to the FBPase class 1 family.	0.498
EEF1AKMT3	LOC103358721	ENSSPAP00000002316	ENSSPAP00000025977	EEF1A lysine methyltransferase 3.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b.	0.527
EEF1AKMT3	LOC103361531	ENSSPAP00000002316	ENSSPAP00000028039	EEF1A lysine methyltransferase 3.	6PF2K domain-containing protein.	0.527
EEF1AKMT3	LOC103375654	ENSSPAP00000002316	ENSSPAP00000027740	EEF1A lysine methyltransferase 3.	Uncharacterized protein.	0.527
EEF1AKMT3	PFKFB2	ENSSPAP00000002316	ENSSPAP00000022696	EEF1A lysine methyltransferase 3.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a.	0.527
EEF1AKMT3	PFKFB4	ENSSPAP00000002316	ENSSPAP00000027985	EEF1A lysine methyltransferase 3.	6PF2K domain-containing protein.	0.527
EEF1AKMT3	fbp2	ENSSPAP00000002316	ENSSPAP00000007781	EEF1A lysine methyltransferase 3.	Fructose-1,6-bisphosphatase 2; Belongs to the FBPase class 1 family.	0.498
EEF1AKMT3	pfkfb1	ENSSPAP00000002316	ENSSPAP00000003351	EEF1A lysine methyltransferase 3.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1.	0.527
EEF1AKMT3	pfkfb2	ENSSPAP00000002316	ENSSPAP00000000228	EEF1A lysine methyltransferase 3.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b.	0.527
EEF1AKMT3	pfkfb3	ENSSPAP00000002316	ENSSPAP00000003235	EEF1A lysine methyltransferase 3.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3.	0.527
ENSSPAP00000001462	ENSSPAP00000008530	ENSSPAP00000001462	ENSSPAP00000008530	Uncharacterized protein.	Uncharacterized protein.	0.713
ENSSPAP00000001462	ENSSPAP00000016231	ENSSPAP00000001462	ENSSPAP00000016231	Uncharacterized protein.	Phosphotransferase.	0.736
ENSSPAP00000001462	ENSSPAP00000019558	ENSSPAP00000001462	ENSSPAP00000019558	Uncharacterized protein.	Phosphotransferase.	0.736
ENSSPAP00000001462	LOC103353278	ENSSPAP00000001462	ENSSPAP00000029952	Uncharacterized protein.	Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family.	0.871
ENSSPAP00000001462	LOC103353425	ENSSPAP00000001462	ENSSPAP00000007752	Uncharacterized protein.	Fructose-1,6-bisphosphatase 1a; Belongs to the FBPase class 1 family.	0.871
ENSSPAP00000001462	LOC103356835	ENSSPAP00000001462	ENSSPAP00000018380	Uncharacterized protein.	Triosephosphate isomerase.	0.865
ENSSPAP00000001462	LOC103358721	ENSSPAP00000001462	ENSSPAP00000025977	Uncharacterized protein.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b.	0.829
ENSSPAP00000001462	LOC103359076	ENSSPAP00000001462	ENSSPAP00000013086	Uncharacterized protein.	Uncharacterized protein.	0.690
ENSSPAP00000001462	LOC103361531	ENSSPAP00000001462	ENSSPAP00000028039	Uncharacterized protein.	6PF2K domain-containing protein.	0.829