(30 nodes) Other glycan degradation network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103353773	Sialidase domain-containing protein. (391 aa)
	manba	Mannosidase, beta A, lysosomal. (815 aa)
	gba	Glucosylceramidase. (411 aa)
	zbtb8b	Zinc finger and BTB domain containing 8B. (527 aa)
	hexa	Beta-hexosaminidase. (571 aa)
	fuca2	Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (454 aa)
	gba2	Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (860 aa)
	ENSSPAP00000023917	Uncharacterized protein. (405 aa)
	ENSSPAP00000023890	Uncharacterized protein. (82 aa)
	LOC103376061	Alpha-L-fucosidase 2. (377 aa)
	fuca1	Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (432 aa)
	hexb	Beta-hexosaminidase. (587 aa)
	hexd	Hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing. (480 aa)
	rabggtb	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (331 aa)
	man2b2	Alpha-mannosidase. (1015 aa)
	LOC103357896	Beta-galactosidase. (620 aa)
	tmem130	Transmembrane protein 130. (305 aa)
	glb1l	Galactosidase, beta 1-like; Belongs to the glycosyl hydrolase 35 family. (640 aa)
	aga	Aspartylglucosaminidase. (346 aa)
	neu4	Sialidase 4. (412 aa)
	engase	Endo-beta-N-acetylglucosaminidase. (724 aa)
	man2b1	Alpha-mannosidase. (1000 aa)
	neu1	Neuraminidase 1. (385 aa)
	fam149b1	Family with sequence similarity 149 member B1. (674 aa)
	LOC103357233	Beta-galactosidase. (599 aa)
	LOC103357232	Beta-galactosidase. (599 aa)
	ENSSPAP00000003693	Uncharacterized protein. (157 aa)
	neu3	Sialidase 3 (membrane sialidase), tandem duplicate 1. (410 aa)
	LOC103369971	Stanniocalcin 2b. (387 aa)
	glb1	Beta-galactosidase. (650 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000003693	fam149b1	ENSSPAP00000003693	ENSSPAP00000006608	Uncharacterized protein.	Family with sequence similarity 149 member B1.	0.617
ENSSPAP00000003693	gba	ENSSPAP00000003693	ENSSPAP00000029925	Uncharacterized protein.	Glucosylceramidase.	0.706
ENSSPAP00000003693	gba2	ENSSPAP00000003693	ENSSPAP00000024265	Uncharacterized protein.	Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.	0.657
ENSSPAP00000003693	hexa	ENSSPAP00000003693	ENSSPAP00000024603	Uncharacterized protein.	Beta-hexosaminidase.	0.619
ENSSPAP00000003693	hexb	ENSSPAP00000003693	ENSSPAP00000018919	Uncharacterized protein.	Beta-hexosaminidase.	0.619
ENSSPAP00000003693	manba	ENSSPAP00000003693	ENSSPAP00000029982	Uncharacterized protein.	Mannosidase, beta A, lysosomal.	0.683
ENSSPAP00000003693	neu1	ENSSPAP00000003693	ENSSPAP00000006767	Uncharacterized protein.	Neuraminidase 1.	0.805
ENSSPAP00000003693	neu4	ENSSPAP00000003693	ENSSPAP00000011698	Uncharacterized protein.	Sialidase 4.	0.613
ENSSPAP00000003693	tmem130	ENSSPAP00000003693	ENSSPAP00000014100	Uncharacterized protein.	Transmembrane protein 130.	0.706
ENSSPAP00000023890	engase	ENSSPAP00000023890	ENSSPAP00000011233	Uncharacterized protein.	Endo-beta-N-acetylglucosaminidase.	0.742
ENSSPAP00000023890	man2b1	ENSSPAP00000023890	ENSSPAP00000009326	Uncharacterized protein.	Alpha-mannosidase.	0.908
ENSSPAP00000023890	man2b2	ENSSPAP00000023890	ENSSPAP00000018427	Uncharacterized protein.	Alpha-mannosidase.	0.908
ENSSPAP00000023890	manba	ENSSPAP00000023890	ENSSPAP00000029982	Uncharacterized protein.	Mannosidase, beta A, lysosomal.	0.509
ENSSPAP00000023917	engase	ENSSPAP00000023917	ENSSPAP00000011233	Uncharacterized protein.	Endo-beta-N-acetylglucosaminidase.	0.742
ENSSPAP00000023917	man2b1	ENSSPAP00000023917	ENSSPAP00000009326	Uncharacterized protein.	Alpha-mannosidase.	0.908
ENSSPAP00000023917	man2b2	ENSSPAP00000023917	ENSSPAP00000018427	Uncharacterized protein.	Alpha-mannosidase.	0.908
ENSSPAP00000023917	manba	ENSSPAP00000023917	ENSSPAP00000029982	Uncharacterized protein.	Mannosidase, beta A, lysosomal.	0.509
LOC103353773	neu1	ENSSPAP00000016365	ENSSPAP00000006767	Sialidase domain-containing protein.	Neuraminidase 1.	0.841
LOC103353773	neu4	ENSSPAP00000016365	ENSSPAP00000011698	Sialidase domain-containing protein.	Sialidase 4.	0.811
LOC103357232	fam149b1	ENSSPAP00000006373	ENSSPAP00000006608	Beta-galactosidase.	Family with sequence similarity 149 member B1.	0.617