STRINGSTRING
ENSSPAP00000005105 ENSSPAP00000005105 eno2 eno2 ppp4r2 ppp4r2 naxe naxe LOC103373921 LOC103373921 LOC103366045 LOC103366045 exosc6 exosc6 PPIC PPIC ENSSPAP00000001462 ENSSPAP00000001462 wdr61 wdr61 lsm3 lsm3 dph2 dph2 ENSSPAP00000000785 ENSSPAP00000000785 LOC103376601 LOC103376601 eno3 eno3 exd2 exd2 ENSSPAP00000004195 ENSSPAP00000004195 patl1 patl1 LOC103353891 LOC103353891 dcps dcps exosc8 exosc8 LOC103363318 LOC103363318 tent4a tent4a helz2 helz2 LOC103364392 LOC103364392 cnot3 cnot3 exosc9 exosc9 mkks mkks pam pam cnot6 cnot6 cct3 cct3 slc30a6 slc30a6 dcp1a dcp1a ENSSPAP00000008883 ENSSPAP00000008883 cnot2 cnot2 LOC103374102 LOC103374102 exosc10 exosc10 LOC103366231 LOC103366231 LOC103368244 LOC103368244 ENSSPAP00000009501 ENSSPAP00000009501 PLXDC1 PLXDC1 cnot8 cnot8 cct5 cct5 LOC103357997 LOC103357997 pde12 pde12 LOC103359615 LOC103359615 ENSSPAP00000019704 ENSSPAP00000019704 pan3 pan3 cnot10 cnot10 LOC103364803 LOC103364803 LOC103360851 LOC103360851 LOC103366440 LOC103366440 LOC103356836 LOC103356836 LOC103360126 LOC103360126 ENSSPAP00000017215 ENSSPAP00000017215 skiv2l skiv2l cct2 cct2 LOC103371967 LOC103371967 ENSSPAP00000016474 ENSSPAP00000016474 cnot4 cnot4 LOC103366853 LOC103366853 btg1 btg1 LOC103372385 LOC103372385 bbs10 bbs10 lsm4 lsm4 LOC103364533 LOC103364533 tcp1 tcp1 ENSSPAP00000015226 ENSSPAP00000015226 ENSSPAP00000015183 ENSSPAP00000015183 LOC103364531 LOC103364531 nudt6 nudt6 mtrex mtrex zcchc2 zcchc2 LOC103359095 LOC103359095 LOC103375326 LOC103375326 btg3 btg3 hspd1 hspd1 cct4 cct4 LOC103373018 LOC103373018 LOC103375937 LOC103375937 LOC103355155 LOC103355155 LOC103365697 LOC103365697 LOC103371878 LOC103371878 toe1 toe1 pabpc4 pabpc4 LOC103357815 LOC103357815 ENSSPAP00000011494 ENSSPAP00000011494 c1d c1d cct6a cct6a noct noct mphosph6 mphosph6 ddx6 ddx6 exosc2 exosc2 cnot6l cnot6l zcchc9 zcchc9 slc30a7 slc30a7 dhx36 dhx36 dhx30 dhx30 LOC103363773 LOC103363773 LOC103362646 LOC103362646 lrrc27 lrrc27 lsm8 lsm8 PLXDC2 PLXDC2 pfkl pfkl dis3l2 dis3l2 ufsp2 ufsp2 zcchc7 zcchc7 TMEM87B TMEM87B lsm1 lsm1 ipo7 ipo7 tob1 tob1 edc3 edc3 tent4b tent4b pan2 pan2 cnbp cnbp wrap73 wrap73 dis3 dis3 ENSSPAP00000025829 ENSSPAP00000025829 dis3l dis3l exosc3 exosc3 lsm5 lsm5 LOC103363900 LOC103363900 slc30a5 slc30a5 arsk arsk cbwd1 cbwd1 patl2 patl2 hspa9 hspa9 ENSSPAP00000005867 ENSSPAP00000005867 exosc7 exosc7 eno1 eno1 LOC103373754 LOC103373754 LOC103371419 LOC103371419 CNOT7 CNOT7 vps72 vps72 cnot1 cnot1 nudt18 nudt18 yjefn3 yjefn3 TMEM87A TMEM87A lsm7 lsm7 PFKP PFKP LOC103358589 LOC103358589 CNOT9 CNOT9 dhx57 dhx57 xrn2 xrn2 ENSSPAP00000021610 ENSSPAP00000021610 LOC103366519 LOC103366519 exosc4 exosc4 edc4 edc4 exosc1 exosc1 lsm2 lsm2 PNPT1 PNPT1 exosc5 exosc5 ipo8 ipo8 TOB2 TOB2 cct7 cct7 LOC103367002 LOC103367002 LOC103359879 LOC103359879
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSSPAP000000051052-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (343 aa)
eno2Uncharacterized protein. (379 aa)
ppp4r2Protein phosphatase 4, regulatory subunit 2a. (410 aa)
naxeNAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (283 aa)
LOC103373921DEAD (Asp-Glu-Ala-Asp) box helicase 61; Belongs to the DEAD box helicase family. (484 aa)
LOC103366045CCR4-NOT transcription complex, subunit 3b. (929 aa)
exosc6Exosome component 6. (274 aa)
PPICPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (179 aa)
ENSSPAP00000001462Uncharacterized protein. (93 aa)
wdr61WD repeat domain 61. (305 aa)
lsm3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (99 aa)
dph22-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. (480 aa)
ENSSPAP00000000785UFM1-specific peptidase 1 (non-functional). (245 aa)
LOC103376601ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (778 aa)
eno3Enolase 3. (433 aa)
exd2Exonuclease 3'-5' domain containing 2. (640 aa)
ENSSPAP00000004195LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
patl1PAT1 homolog 1, processing body mRNA decay factor. (752 aa)
LOC103353891Si:dkey-12j5.1. (415 aa)
dcpsDecapping enzyme, scavenger. (330 aa)
exosc8Exosome component 8. (277 aa)
LOC103363318CCR4-NOT transcription complex subunit 9. (297 aa)
tent4aTerminal nucleotidyltransferase 4A. (544 aa)
helz2C3H1-type domain-containing protein. (2910 aa)
LOC103364392PSI domain-containing protein. (359 aa)
cnot3CCR4-NOT transcription complex, subunit 3a. (891 aa)
exosc9Exosome component 9. (420 aa)
mkksMcKusick-Kaufman syndrome. (567 aa)
pamPeptidylglycine alpha-amidating monooxygenase. (886 aa)
cnot6CCR4-NOT transcription complex, subunit 6a. (559 aa)
cct3T-complex protein 1 subunit gamma. (540 aa)
slc30a6Solute carrier family 30 member 6. (499 aa)
dcp1aDecapping mRNA 1A. (506 aa)
ENSSPAP00000008883Uncharacterized protein. (58 aa)
cnot2CCR4-NOT transcription complex, subunit 2. (451 aa)
LOC103374102Protein phosphatase 4, regulatory subunit 2b. (437 aa)
exosc10Exosome component 10. (892 aa)
LOC103366231Poly(A)-specific ribonuclease (deadenylation nuclease). (682 aa)
LOC103368244ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
ENSSPAP00000009501Uncharacterized protein. (199 aa)
PLXDC1Plexin domain containing 1. (489 aa)
cnot8CCR4-NOT transcription complex, subunit 8. (285 aa)
cct5Chaperonin containing TCP1, subunit 5 (epsilon). (541 aa)
LOC103357997Uncharacterized protein. (214 aa)
pde12Phosphodiesterase 12. (591 aa)
LOC103359615Si:dkey-79d12.5. (289 aa)
ENSSPAP00000019704Decapping mRNA 2. (248 aa)
pan3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (793 aa)
cnot10CCR4-NOT transcription complex, subunit 10. (755 aa)
LOC103364803Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (635 aa)
LOC103360851Si:ch211-106h4.6. (493 aa)
LOC103366440NOT2_3_5 domain-containing protein. (536 aa)
LOC103356836Enolase 2. (434 aa)
LOC103360126Uncharacterized protein; Belongs to the DEAD box helicase family. (489 aa)
ENSSPAP00000017215Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (196 aa)
skiv2lSKI2 homolog, superkiller viralicidic activity 2-like. (1188 aa)
cct2Chaperonin containing TCP1, subunit 2 (beta). (535 aa)
LOC103371967DUF3715 domain-containing protein. (2814 aa)
ENSSPAP00000016474Uncharacterized protein. (133 aa)
cnot4CCR4-NOT transcription complex, subunit 4a. (798 aa)
LOC103366853CCR4-NOT transcription complex, subunit 7. (248 aa)
btg1B-cell translocation gene 1, anti-proliferative. (182 aa)
LOC1033723856-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (745 aa)
bbs10Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (655 aa)
lsm4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (151 aa)
LOC103364533ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1292 aa)
tcp1T-complex 1. (558 aa)
ENSSPAP00000015226Helicase ATP-binding domain-containing protein. (216 aa)
ENSSPAP00000015183Uncharacterized protein. (101 aa)
LOC103364531DEAH (Asp-Glu-Ala-His) box polypeptide 29. (1094 aa)
nudt6Nudix (nucleoside diphosphate linked moiety X)-type motif 6. (313 aa)
mtrexMtr4 exosome RNA helicase. (1006 aa)
zcchc2CCHC-type domain-containing protein. (1155 aa)
LOC103359095Transducer of ERBB2, 1b. (338 aa)
LOC103375326Endo/exonuclease/phosphatase domain-containing protein. (367 aa)
btg3B-cell translocation gene 3. (235 aa)
hspd1Heat shock 60 protein 1; Belongs to the chaperonin (HSP60) family. (575 aa)
cct4Chaperonin containing TCP1, subunit 4 (delta). (645 aa)
LOC103373018Uncharacterized protein. (205 aa)
LOC103375937Enhancer of mRNA decapping 3 homolog (S. cerevisiae). (478 aa)
LOC103355155Uncharacterized protein. (562 aa)
LOC103365697Ankyrin repeat and KH domain containing 1. (2220 aa)
LOC103371878Zgc:103759. (218 aa)
toe1Target of EGR1, exonuclease. (526 aa)
pabpc4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (627 aa)
LOC103357815Zgc:153119. (306 aa)
ENSSPAP00000011494Uncharacterized protein. (117 aa)
c1dC1D nuclear receptor corepressor. (155 aa)
cct6aChaperonin containing TCP1, subunit 6A (zeta 1). (531 aa)
noctNocturnin. (465 aa)
mphosph6M-phase phosphoprotein 6. (163 aa)
ddx6DEAD (Asp-Glu-Ala-Asp) box helicase 6; Belongs to the DEAD box helicase family. (482 aa)
exosc2Exosome component 2. (293 aa)
cnot6lCCR4-NOT transcription complex, subunit 6-like. (553 aa)
zcchc9Zinc finger, CCHC domain containing 9. (270 aa)
slc30a7Solute carrier family 30 member 7. (395 aa)
dhx36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1066 aa)
dhx30DEAH (Asp-Glu-Ala-His) box helicase 30. (1167 aa)
LOC103363773CCHC-type zinc finger, nucleic acid binding protein b. (138 aa)
LOC103362646Uncharacterized protein. (531 aa)
lrrc27Uncharacterized protein. (428 aa)
lsm8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
PLXDC2Plexin domain containing 2. (531 aa)
pfklATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1052 aa)
ufsp2Ufm1-specific peptidase 2. (469 aa)
zcchc7Zinc finger, CCHC domain containing 7. (663 aa)
TMEM87BTransmembrane protein 87B. (588 aa)
lsm1U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (133 aa)
ipo7Importin 7. (1039 aa)
tob1Transducer of ERBB2, 1a. (319 aa)
edc3Enhancer of mRNA decapping 3. (474 aa)
tent4bTerminal nucleotidyltransferase 4B. (684 aa)
pan2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1210 aa)
cnbpCCHC-type zinc finger, nucleic acid binding protein a. (167 aa)
wrap73WD repeat containing, antisense to TP73. (449 aa)
dis3DIS3 exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (951 aa)
ENSSPAP00000025829Uncharacterized protein. (143 aa)
dis3lDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1043 aa)
exosc3Exosome component 3. (244 aa)
lsm5LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated. (59 aa)
LOC103363900B-cell translocation gene 4. (265 aa)
slc30a5Solute carrier family 30 member 5. (782 aa)
arskTetratricopeptide repeat domain 37. (1582 aa)
cbwd1COBW domain containing. (385 aa)
patl2PAT1 homolog 2. (625 aa)
hspa9Heat shock protein 9; Belongs to the heat shock protein 70 family. (683 aa)
ENSSPAP00000005867Si:dkey-81h8.1. (114 aa)
exosc7Exosome component 7. (291 aa)
eno1Enolase 1a, (alpha). (432 aa)
LOC103373754Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (557 aa)
LOC103371419Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (633 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (249 aa)
vps72Vacuolar protein sorting 72 homolog a. (367 aa)
cnot1CCR4-NOT transcription complex, subunit 1. (2333 aa)
nudt18Nudix (nucleoside diphosphate linked moiety X)-type motif 18; Belongs to the Nudix hydrolase family. (338 aa)
yjefn3YjeF N-terminal domain containing 3. (249 aa)
TMEM87ATransmembrane protein 87A. (550 aa)
lsm7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (167 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (788 aa)
LOC103358589Uncharacterized protein. (491 aa)
CNOT9CCR4-NOT transcription complex subunit 9. (299 aa)
dhx57DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57. (1324 aa)
xrn25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (971 aa)
ENSSPAP00000021610Enolase 4. (323 aa)
LOC103366519Transmembrane protein 176. (219 aa)
exosc4Exosome component 4. (264 aa)
edc4Enhancer of mRNA decapping 4. (1390 aa)
exosc1Exosome component 1. (213 aa)
lsm2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (770 aa)
exosc5Exosome component 5. (220 aa)
ipo8Importin 8. (1019 aa)
TOB2Transducer of ERBB2, 2. (328 aa)
cct7T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (545 aa)
LOC103367002Uncharacterized protein. (811 aa)
LOC103359879Enolase 1b, (alpha). (433 aa)
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
Server load: medium (48%) [HD]