STRINGSTRING
ANB03574.1 ANB03574.1 ftsZ ftsZ ftsA ftsA ftsQ ftsQ ddl ddl murB murB murG murG ftsW ftsW murD murD mraY mraY murF murF murE murE ftsI ftsI ftsL ftsL rsmH rsmH mraZ mraZ ftsE ftsE ANB01419.1 ANB01419.1 ANB01435.1 ANB01435.1 mnmE mnmE gidA gidA rsmG rsmG ANB01920.1 ANB01920.1 ANB03704.1 ANB03704.1 ANB03705.1 ANB03705.1 ANB02016.1 ANB02016.1 ANB02017.1 ANB02017.1 ANB02018.1 ANB02018.1 ANB02102.1 ANB02102.1 ANB03734.1 ANB03734.1 bpt bpt ANB02327.1 ANB02327.1 rsmA rsmA ANB02331.1 ANB02331.1 pdxA pdxA surA surA mrdA mrdA mrdB mrdB ANB02339.1 ANB02339.1 rlpA rlpA ANB02340.1 ANB02340.1 ANB02342.1 ANB02342.1 ANB02500.1 ANB02500.1 ANB02676.1 ANB02676.1 ANB02681.1 ANB02681.1 mpl mpl minC minC ANB02721.1 ANB02721.1 minE minE aat aat ANB03838.1 ANB03838.1 ANB02725.1 ANB02725.1 lolA lolA ANB02727.1 ANB02727.1 ANB02737.1 ANB02737.1 ANB02811.1 ANB02811.1 ftsB ftsB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANB03574.1Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (756 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (403 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (411 aa)
ftsQCell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (253 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (311 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (300 aa)
murGUDP-diphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (362 aa)
ftsWCell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (396 aa)
murDUDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (438 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (459 aa)
murEUDP-N-acetylmuramyl peptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (502 aa)
ftsICell division protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (571 aa)
ftsLCell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (74 aa)
rsmH16S rRNA methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (327 aa)
mraZCell division protein MraZ; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MraZ family. (150 aa)
ftsECell division protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (224 aa)
ANB01419.1Cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (319 aa)
ANB01435.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (814 aa)
mnmEtRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (446 aa)
gidAtRNA uridine 5-carboxymethylaminomethyl modification protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (630 aa)
rsmG16S rRNA methyltransferase; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (204 aa)
ANB01920.1Chromosome partitioning protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
ANB03704.1Chromosome partitioning protein ParB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ParB family. (287 aa)
ANB03705.1Peptidase M23; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
ANB02016.1Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. (163 aa)
ANB02017.1Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. (292 aa)
ANB02018.1Rod shape-determining protein MreB; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
ANB02102.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
ANB03734.1Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
bptarginyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily. (235 aa)
ANB02327.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (868 aa)
rsmARibosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (259 aa)
ANB02331.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (338 aa)
surAMolecular chaperone SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (456 aa)
mrdAPenicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (615 aa)
mrdBRod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (372 aa)
ANB02339.1Lytic murein transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
rlpALipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (276 aa)
ANB02340.1D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (390 aa)
ANB02342.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0250 family. (92 aa)
ANB02500.1N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
ANB02676.1D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
ANB02681.1Cobyric acid synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
mplUDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (441 aa)
minCSeptum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (251 aa)
ANB02721.1ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
minECell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (85 aa)
aatleucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. (241 aa)
ANB03838.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
ANB02725.1Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology. (810 aa)
lolACell envelope biogenesis protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (205 aa)
ANB02727.1Recombination factor protein RarA; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
ANB02737.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
ANB02811.1Cobalamin biosynthesis protein CobQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
ftsBCell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (97 aa)
Your Current Organism:
Ectothiorhodospira sp. BSL9
NCBI taxonomy Id: 1442136
Other names: E. sp. BSL-9, Ectothiorhodospira sp. BSL-9
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