STRINGSTRING
mutM mutM ANB01409.1 ANB01409.1 nth nth ANB01826.1 ANB01826.1 polA polA ANB01913.1 ANB01913.1 ANB03733.1 ANB03733.1 ANB03809.1 ANB03809.1 ANB03048.1 ANB03048.1 ANB03248.1 ANB03248.1 ligA ligA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mutM5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (271 aa)
ANB01409.15'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (210 aa)
ANB01826.1Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (903 aa)
ANB01913.1DNA-(apurinic or apyrimidinic site) lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
ANB03733.1DNA glycosylase; Adenine glycosylase active on G-A mispairs. (368 aa)
ANB03809.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
ANB03048.1ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
ANB03248.1SPO1 DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
ligANAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (684 aa)
Your Current Organism:
Ectothiorhodospira sp. BSL9
NCBI taxonomy Id: 1442136
Other names: E. sp. BSL-9, Ectothiorhodospira sp. BSL-9
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.