STRINGSTRING
Z517_03031 Z517_03031 Z517_02825 Z517_02825 Z517_02770 Z517_02770 Z517_00935 Z517_00935 Z517_00136 Z517_00136 Z517_10674 Z517_10674 Z517_10548 Z517_10548 Z517_03284 Z517_03284 Z517_04163 Z517_04163 Z517_11614 Z517_11614 Z517_12194 Z517_12194 Z517_02001 Z517_02001 Z517_06685 Z517_06685 Z517_08810 Z517_08810 Z517_04233 Z517_04233 Z517_07219 Z517_07219 Z517_07968 Z517_07968 MDE1 MDE1 Z517_05805 Z517_05805 Z517_11226 Z517_11226 Z517_08249 Z517_08249 Z517_09914 Z517_09914 Z517_09674 Z517_09674 Z517_11999 Z517_11999 Z517_11935 Z517_11935 Z517_01662 Z517_01662 Z517_01557 Z517_01557 Z517_01421 Z517_01421 Z517_00539 Z517_00539 PSD2 PSD2 Z517_02378 Z517_02378 cyn1 cyn1 Z517_01009 Z517_01009 Z517_03203 Z517_03203 Z517_05619 Z517_05619 Z517_04065 Z517_04065 Z517_06782 Z517_06782 Z517_06114 Z517_06114 Z517_08197 Z517_08197 Z517_10602 Z517_10602 Z517_10264 Z517_10264 Z517_10118 Z517_10118 Z517_11753 Z517_11753 Z517_01008 Z517_01008 Z517_00289 Z517_00289 Z517_02591 Z517_02591 Z517_02174 Z517_02174 Z517_08176 Z517_08176 Z517_07498 Z517_07498 Z517_10806 Z517_10806 Z517_11857 Z517_11857 Z517_11411 Z517_11411 Z517_11386 Z517_11386 Z517_12441 Z517_12441 NTH1 NTH1 PSD1 PSD1 Z517_04289 Z517_04289 Z517_06794 Z517_06794 Z517_01263 Z517_01263 Z517_01067 Z517_01067 Z517_00820 Z517_00820 Z517_08362 Z517_08362 Z517_09985 Z517_09985
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Z517_03031Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (360 aa)
Z517_02825ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (348 aa)
Z517_02770Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (229 aa)
Z517_00935Unplaced genomic scaffold supercont1.1, whole genome shotgun sequence; Belongs to the DapA family. (327 aa)
Z517_00136Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (179 aa)
Z517_10674Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (192 aa)
Z517_10548Unplaced genomic scaffold supercont1.7, whole genome shotgun sequence; Belongs to the DapA family. (319 aa)
Z517_03284Unplaced genomic scaffold supercont1.2, whole genome shotgun sequence; Belongs to the metallo-dependent hydrolases superfamily. (338 aa)
Z517_04163Unplaced genomic scaffold supercont1.3, whole genome shotgun sequence; Belongs to the metallo-dependent hydrolases superfamily. (336 aa)
Z517_11614Unplaced genomic scaffold supercont1.8, whole genome shotgun sequence; Belongs to the metallo-dependent hydrolases superfamily. (388 aa)
Z517_12194Unplaced genomic scaffold supercont1.9, whole genome shotgun sequence; Belongs to the scytalone dehydratase family. (173 aa)
Z517_02001Isocitrate lyase. (564 aa)
Z517_06685Threonine dehydratase. (563 aa)
Z517_088103,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (240 aa)
Z517_042333-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (772 aa)
Z517_07219Unplaced genomic scaffold supercont1.4, whole genome shotgun sequence; Belongs to the metallo-dependent hydrolases superfamily. (328 aa)
Z517_07968Tryptophan synthase. (738 aa)
MDE1Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (238 aa)
Z517_05805Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (768 aa)
Z517_11226Unplaced genomic scaffold supercont1.7, whole genome shotgun sequence. (583 aa)
Z517_08249Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
Z517_09914Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (273 aa)
Z517_09674Unplaced genomic scaffold supercont1.6, whole genome shotgun sequence; Belongs to the DapA family. (302 aa)
Z517_11999Unplaced genomic scaffold supercont1.8, whole genome shotgun sequence; Belongs to the metallo-dependent hydrolases superfamily. (289 aa)
Z517_11935Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (543 aa)
Z517_01662Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (232 aa)
Z517_01557tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (312 aa)
Z517_01421Unplaced genomic scaffold supercont1.1, whole genome shotgun sequence; Belongs to the metallo-dependent hydrolases superfamily. (387 aa)
Z517_00539Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (170 aa)
PSD2Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily. (1104 aa)
Z517_02378Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (182 aa)
cyn1Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family. (160 aa)
Z517_01009Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (396 aa)
Z517_032033-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family. In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family. (1617 aa)
Z517_05619Chorismate synthase. (424 aa)
Z517_04065Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (351 aa)
Z517_06782Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (604 aa)
Z517_06114Unplaced genomic scaffold supercont1.4, whole genome shotgun sequence; Belongs to the metallo-dependent hydrolases superfamily. (365 aa)
Z517_08197Unplaced genomic scaffold supercont1.5, whole genome shotgun sequence. (594 aa)
Z517_10602Unplaced genomic scaffold supercont1.7, whole genome shotgun sequence; Belongs to the metallo-dependent hydrolases superfamily. (329 aa)
Z517_10264Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (774 aa)
Z517_10118Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (292 aa)
Z517_11753Isocitrate lyase. (537 aa)
Z517_01008Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (328 aa)
Z517_00289Unplaced genomic scaffold supercont1.1, whole genome shotgun sequence; Belongs to the metallo-dependent hydrolases superfamily. (288 aa)
Z517_02591Unplaced genomic scaffold supercont1.2, whole genome shotgun sequence; Belongs to the DapA family. (319 aa)
Z517_02174Unplaced genomic scaffold supercont1.2, whole genome shotgun sequence; Belongs to the metallo-dependent hydrolases superfamily. (338 aa)
Z517_08176Unplaced genomic scaffold supercont1.5, whole genome shotgun sequence; Belongs to the metallo-dependent hydrolases superfamily. (316 aa)
Z517_07498Unplaced genomic scaffold supercont1.5, whole genome shotgun sequence; Belongs to the DapA family. (337 aa)
Z517_10806Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (429 aa)
Z517_11857Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (763 aa)
Z517_11411Unplaced genomic scaffold supercont1.8, whole genome shotgun sequence; Belongs to the metallo-dependent hydrolases superfamily. (380 aa)
Z517_11386Glutamate decarboxylase; Belongs to the group II decarboxylase family. (526 aa)
Z517_12441Putative glutathione-dependent formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family. (190 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (433 aa)
PSD1Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. (537 aa)
Z517_04289Unplaced genomic scaffold supercont1.3, whole genome shotgun sequence. (527 aa)
Z517_06794Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (237 aa)
Z517_01263Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (808 aa)
Z517_01067Phenylalanine ammonia-lyase. (753 aa)
Z517_00820Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (300 aa)
Z517_08362Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (583 aa)
Z517_09985Unplaced genomic scaffold supercont1.6, whole genome shotgun sequence; Belongs to the scytalone dehydratase family. (188 aa)
Your Current Organism:
Fonsecaea pedrosoi
NCBI taxonomy Id: 1442368
Other names: F. pedrosoi CBS 271.37, Fonsecaea pedrosoi CBS 271.37
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