(12 nodes) CMG complex, and Unwinding of DNA network (Rhinocladiella mackenziei)

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second shell of interactors

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Predicted Interactions

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Your Input:
	Z518_08303	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (249 aa)
	Z518_07436	DNA helicase; Belongs to the MCM family. (1007 aa)
	Z518_07192	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (266 aa)
	Z518_05534	annotation not available (231 aa)
	Z518_07064	annotation not available (791 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (814 aa)
	Z518_03703	DNA helicase; Belongs to the MCM family. (863 aa)
	Z518_04276	annotation not available (183 aa)
	Z518_00705	DNA helicase; Belongs to the MCM family. (726 aa)
	Z518_01217	DNA helicase; Belongs to the MCM family. (956 aa)
	Z518_06972	annotation not available (838 aa)
	Z518_06087	DNA helicase; Belongs to the MCM family. (903 aa)

Your Current Organism:

Rhinocladiella mackenziei

NCBI taxonomy Id: 1442369
Other names: R. mackenziei CBS 650.93, Rhinocladiella mackenziei CBS 650.93

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	Z518_00705	A0A0D2IMR7	A0A0D2IU86	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	Z518_01217	A0A0D2IMR7	A0A0D2J384	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	Z518_03703	A0A0D2IMR7	A0A0D2IRE4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	Z518_04276	A0A0D2IMR7	A0A0D2ISY5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	annotation not available	0.995
MCM7	Z518_05534	A0A0D2IMR7	A0A0D2IFS2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	annotation not available	0.993
MCM7	Z518_06087	A0A0D2IMR7	A0A0D2J828	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	Z518_06972	A0A0D2IMR7	A0A0D2J386	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	annotation not available	0.998
MCM7	Z518_07064	A0A0D2IMR7	A0A0D2IJX7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	annotation not available	0.996
MCM7	Z518_07192	A0A0D2IMR7	A0A0D2ICQ3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.	0.992
MCM7	Z518_07436	A0A0D2IMR7	A0A0D2H0D3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	Z518_08303	A0A0D2IMR7	A0A0D2FK58	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	0.992
Z518_00705	MCM7	A0A0D2IU86	A0A0D2IMR7	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
Z518_00705	Z518_01217	A0A0D2IU86	A0A0D2J384	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
Z518_00705	Z518_03703	A0A0D2IU86	A0A0D2IRE4	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
Z518_00705	Z518_04276	A0A0D2IU86	A0A0D2ISY5	DNA helicase; Belongs to the MCM family.	annotation not available	0.995
Z518_00705	Z518_05534	A0A0D2IU86	A0A0D2IFS2	DNA helicase; Belongs to the MCM family.	annotation not available	0.995
Z518_00705	Z518_06087	A0A0D2IU86	A0A0D2J828	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
Z518_00705	Z518_06972	A0A0D2IU86	A0A0D2J386	DNA helicase; Belongs to the MCM family.	annotation not available	0.999
Z518_00705	Z518_07064	A0A0D2IU86	A0A0D2IJX7	DNA helicase; Belongs to the MCM family.	annotation not available	0.992
Z518_00705	Z518_07192	A0A0D2IU86	A0A0D2ICQ3	DNA helicase; Belongs to the MCM family.	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.	0.993