STRINGSTRING
Z518_10764 Z518_10764 Z518_10849 Z518_10849 Z518_10411 Z518_10411 Z518_09188 Z518_09188 ADK2 ADK2 Z518_07971 Z518_07971 Z518_08599 Z518_08599 Z518_06769 Z518_06769 Z518_06874 Z518_06874 Z518_06899 Z518_06899 Z518_05964 Z518_05964 Z518_06059 Z518_06059 Z518_06184 Z518_06184 Z518_03825 Z518_03825 Z518_03835 Z518_03835 Z518_04333 Z518_04333 Z518_04833 Z518_04833 Z518_00692 Z518_00692 Z518_00763 Z518_00763 Z518_01158 Z518_01158 ADK1 ADK1 Z518_10840 Z518_10840 Z518_10865 Z518_10865 Z518_07892 Z518_07892 Z518_07942 Z518_07942 Z518_08007 Z518_08007 Z518_08314 Z518_08314 Z518_08806 Z518_08806 Z518_07361 Z518_07361 Z518_07747 Z518_07747 Z518_05231 Z518_05231 Z518_05306 Z518_05306 Z518_05930 Z518_05930 Z518_03730 Z518_03730 Z518_03750 Z518_03750 Z518_03982 Z518_03982 Z518_02201 Z518_02201 Z518_02457 Z518_02457 Z518_02713 Z518_02713 Z518_02824 Z518_02824 Z518_02869 Z518_02869 Z518_03445 Z518_03445 Z518_00457 Z518_00457 Z518_00754 Z518_00754 Z518_01304 Z518_01304 Z518_10966 Z518_10966 Z518_10619 Z518_10619 Z518_07853 Z518_07853 Z518_11358 Z518_11358 Z518_08445 Z518_08445 Z518_10450 Z518_10450 Z518_06564 Z518_06564 Z518_06674 Z518_06674 Z518_09766 Z518_09766 Z518_07032 Z518_07032 Z518_07267 Z518_07267 Z518_09016 Z518_09016 Z518_09217 Z518_09217 Z518_09407 Z518_09407 Z518_07860 Z518_07860 Z518_08819 Z518_08819 Z518_06411 Z518_06411 Z518_04118 Z518_04118 Z518_07279 Z518_07279 Z518_07494 Z518_07494 Z518_04540 Z518_04540 Z518_07609 Z518_07609 Z518_05198 Z518_05198 Z518_05576 Z518_05576 Z518_02162 Z518_02162 Z518_02167 Z518_02167 Z518_02192 Z518_02192 Z518_02252 Z518_02252 Z518_05958 Z518_05958 AAH1 AAH1 Z518_06078 Z518_06078 Z518_02603 Z518_02603 Z518_02840 Z518_02840 Z518_02930 Z518_02930 Z518_11402 Z518_11402 Z518_03965 Z518_03965 Z518_04140 Z518_04140 Z518_04246 Z518_04246 Z518_10792 Z518_10792 Z518_10827 Z518_10827 Z518_10892 Z518_10892 Z518_04427 Z518_04427 Z518_00564 Z518_00564 Z518_04717 Z518_04717 Z518_00810 Z518_00810 Z518_04932 Z518_04932 Z518_01924 Z518_01924 Z518_02129 Z518_02129 Z518_01446 Z518_01446 AAH1-2 AAH1-2 Z518_01678 Z518_01678 Z518_02822 Z518_02822 Z518_08486 Z518_08486 Z518_08531 Z518_08531 Z518_00742 Z518_00742 Z518_01032 Z518_01032 Z518_07123 Z518_07123 Z518_01428 Z518_01428 Z518_07143 Z518_07143 Z518_07153 Z518_07153 Z518_07348 Z518_07348 Z518_07398 Z518_07398 Z518_07593 Z518_07593 Z518_05540 Z518_05540 Z518_05932 Z518_05932 Z518_06222 Z518_06222 Z518_03702 Z518_03702 Z518_03884 Z518_03884 Z518_02796 Z518_02796 Z518_02931 Z518_02931 Z518_00163 Z518_00163 Z518_00741 Z518_00741 Z518_01176 Z518_01176 Z518_01447 Z518_01447 Z518_01553 Z518_01553 Z518_01734 Z518_01734
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Z518_10764annotation not available (545 aa)
Z518_10849annotation not available (227 aa)
Z518_10411annotation not available (249 aa)
Z518_09188annotation not available (385 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (259 aa)
Z518_07971annotation not available (810 aa)
Z518_08599annotation not available (602 aa)
Z518_06769annotation not available (156 aa)
Z518_06874annotation not available (608 aa)
Z518_06899annotation not available (257 aa)
Z518_05964annotation not available (159 aa)
Z518_06059annotation not available (306 aa)
Z518_06184annotation not available (685 aa)
Z518_03825annotation not available (748 aa)
Z518_03835annotation not available (1093 aa)
Z518_04333annotation not available (402 aa)
Z518_04833annotation not available (939 aa)
Z518_00692annotation not available (610 aa)
Z518_00763annotation not available (506 aa)
Z518_01158annotation not available (338 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (274 aa)
Z518_10840annotation not available (599 aa)
Z518_10865annotation not available (279 aa)
Z518_07892annotation not available (479 aa)
Z518_07942annotation not available (363 aa)
Z518_080073,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (236 aa)
Z518_08314annotation not available (464 aa)
Z518_08806Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (404 aa)
Z518_07361annotation not available (406 aa)
Z518_07747annotation not available (153 aa)
Z518_05231annotation not available (213 aa)
Z518_05306annotation not available (284 aa)
Z518_05930annotation not available (442 aa)
Z518_03730annotation not available (583 aa)
Z518_037503-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (338 aa)
Z518_03982annotation not available (781 aa)
Z518_02201annotation not available (413 aa)
Z518_02457annotation not available (600 aa)
Z518_02713annotation not available (272 aa)
Z518_02824annotation not available (340 aa)
Z518_02869annotation not available (323 aa)
Z518_03445Belongs to the GDA1/CD39 NTPase family. (574 aa)
Z518_00457annotation not available (593 aa)
Z518_00754annotation not available (343 aa)
Z518_01304annotation not available (175 aa)
Z518_10966annotation not available (610 aa)
Z518_10619Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (495 aa)
Z518_07853annotation not available (314 aa)
Z518_11358annotation not available (1377 aa)
Z518_08445annotation not available (269 aa)
Z518_104506,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (228 aa)
Z518_06564annotation not available (451 aa)
Z518_06674annotation not available (241 aa)
Z518_09766Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (476 aa)
Z518_07032annotation not available (266 aa)
Z518_07267Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (604 aa)
Z518_09016annotation not available (346 aa)
Z518_09217annotation not available (588 aa)
Z518_09407annotation not available (1065 aa)
Z518_07860annotation not available (435 aa)
Z518_08819annotation not available (385 aa)
Z518_06411annotation not available (287 aa)
Z518_04118Belongs to the 5'-nucleotidase family. (597 aa)
Z518_07279S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (312 aa)
Z518_07494annotation not available (281 aa)
Z518_04540annotation not available (598 aa)
Z518_07609annotation not available (425 aa)
Z518_05198annotation not available (385 aa)
Z518_05576annotation not available (240 aa)
Z518_02162annotation not available (213 aa)
Z518_02167Phosphodiesterase. (1057 aa)
Z518_02192annotation not available (280 aa)
Z518_02252annotation not available (620 aa)
Z518_05958Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (936 aa)
AAH1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (350 aa)
Z518_06078annotation not available (243 aa)
Z518_02603annotation not available (640 aa)
Z518_02840Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (550 aa)
Z518_02930annotation not available (262 aa)
Z518_11402annotation not available (410 aa)
Z518_03965Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
Z518_04140annotation not available (366 aa)
Z518_04246annotation not available (1438 aa)
Z518_10792annotation not available (231 aa)
Z518_10827Belongs to the GDA1/CD39 NTPase family. (699 aa)
Z518_10892annotation not available (206 aa)
Z518_04427annotation not available (284 aa)
Z518_00564annotation not available (613 aa)
Z518_04717annotation not available (387 aa)
Z518_00810annotation not available (306 aa)
Z518_04932Belongs to the adenylate kinase family. (171 aa)
Z518_01924annotation not available (611 aa)
Z518_02129annotation not available (347 aa)
Z518_01446Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (191 aa)
AAH1-2Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (346 aa)
Z518_01678annotation not available (794 aa)
Z518_02822Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (460 aa)
Z518_08486annotation not available (468 aa)
Z518_08531annotation not available (222 aa)
Z518_00742annotation not available (226 aa)
Z518_01032Belongs to the 5'-nucleotidase family. (622 aa)
Z518_071233-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (272 aa)
Z518_01428annotation not available (520 aa)
Z518_07143annotation not available (407 aa)
Z518_07153annotation not available (523 aa)
Z518_07348Belongs to the dihydrofolate reductase family. (383 aa)
Z518_07398CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (562 aa)
Z518_07593annotation not available (159 aa)
Z518_05540annotation not available (433 aa)
Z518_05932annotation not available (318 aa)
Z518_06222annotation not available (439 aa)
Z518_03702annotation not available (910 aa)
Z518_03884annotation not available (1781 aa)
Z518_02796annotation not available (479 aa)
Z518_02931annotation not available (152 aa)
Z518_00163annotation not available (437 aa)
Z518_00741Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (465 aa)
Z518_01176annotation not available (238 aa)
Z518_01447Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (193 aa)
Z518_01553annotation not available (192 aa)
Z518_01734annotation not available (254 aa)
Your Current Organism:
Rhinocladiella mackenziei
NCBI taxonomy Id: 1442369
Other names: R. mackenziei CBS 650.93, Rhinocladiella mackenziei CBS 650.93
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