STRINGSTRING
Z518_10764 Z518_10764 Z518_10849 Z518_10849 Z518_10411 Z518_10411 Z518_09188 Z518_09188 ADK2 ADK2 Z518_06874 Z518_06874 Z518_05964 Z518_05964 Z518_06059 Z518_06059 Z518_06184 Z518_06184 Z518_04833 Z518_04833 Z518_01158 Z518_01158 ADK1 ADK1 Z518_10865 Z518_10865 Z518_08806 Z518_08806 Z518_07361 Z518_07361 Z518_05231 Z518_05231 Z518_05930 Z518_05930 Z518_02457 Z518_02457 Z518_02713 Z518_02713 Z518_02869 Z518_02869 Z518_03445 Z518_03445 Z518_00457 Z518_00457 Z518_11358 Z518_11358 Z518_06564 Z518_06564 Z518_09766 Z518_09766 Z518_07032 Z518_07032 Z518_07267 Z518_07267 Z518_09016 Z518_09016 Z518_09407 Z518_09407 Z518_08819 Z518_08819 Z518_07279 Z518_07279 Z518_07494 Z518_07494 Z518_04540 Z518_04540 Z518_05576 Z518_05576 Z518_02162 Z518_02162 Z518_02167 Z518_02167 Z518_05958 Z518_05958 AAH1 AAH1 Z518_02840 Z518_02840 Z518_02930 Z518_02930 Z518_03965 Z518_03965 Z518_10827 Z518_10827 Z518_10892 Z518_10892 Z518_00810 Z518_00810 Z518_01924 Z518_01924 Z518_01446 Z518_01446 AAH1-2 AAH1-2 Z518_01678 Z518_01678 Z518_02822 Z518_02822 Z518_08486 Z518_08486 Z518_00742 Z518_00742 Z518_01032 Z518_01032 Z518_07348 Z518_07348 Z518_07398 Z518_07398 Z518_07593 Z518_07593 Z518_03702 Z518_03702 Z518_02931 Z518_02931 Z518_00163 Z518_00163 Z518_00741 Z518_00741 Z518_01176 Z518_01176 Z518_01447 Z518_01447 Z518_01734 Z518_01734
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Z518_10764annotation not available (545 aa)
Z518_10849annotation not available (227 aa)
Z518_10411annotation not available (249 aa)
Z518_09188annotation not available (385 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (259 aa)
Z518_06874annotation not available (608 aa)
Z518_05964annotation not available (159 aa)
Z518_06059annotation not available (306 aa)
Z518_06184annotation not available (685 aa)
Z518_04833annotation not available (939 aa)
Z518_01158annotation not available (338 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (274 aa)
Z518_10865annotation not available (279 aa)
Z518_08806Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (404 aa)
Z518_07361annotation not available (406 aa)
Z518_05231annotation not available (213 aa)
Z518_05930annotation not available (442 aa)
Z518_02457annotation not available (600 aa)
Z518_02713annotation not available (272 aa)
Z518_02869annotation not available (323 aa)
Z518_03445Belongs to the GDA1/CD39 NTPase family. (574 aa)
Z518_00457annotation not available (593 aa)
Z518_11358annotation not available (1377 aa)
Z518_06564annotation not available (451 aa)
Z518_09766Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (476 aa)
Z518_07032annotation not available (266 aa)
Z518_07267Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (604 aa)
Z518_09016annotation not available (346 aa)
Z518_09407annotation not available (1065 aa)
Z518_08819annotation not available (385 aa)
Z518_07279S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (312 aa)
Z518_07494annotation not available (281 aa)
Z518_04540annotation not available (598 aa)
Z518_05576annotation not available (240 aa)
Z518_02162annotation not available (213 aa)
Z518_02167Phosphodiesterase. (1057 aa)
Z518_05958Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (936 aa)
AAH1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (350 aa)
Z518_02840Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (550 aa)
Z518_02930annotation not available (262 aa)
Z518_03965Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
Z518_10827Belongs to the GDA1/CD39 NTPase family. (699 aa)
Z518_10892annotation not available (206 aa)
Z518_00810annotation not available (306 aa)
Z518_01924annotation not available (611 aa)
Z518_01446Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (191 aa)
AAH1-2Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (346 aa)
Z518_01678annotation not available (794 aa)
Z518_02822Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (460 aa)
Z518_08486annotation not available (468 aa)
Z518_00742annotation not available (226 aa)
Z518_01032Belongs to the 5'-nucleotidase family. (622 aa)
Z518_07348Belongs to the dihydrofolate reductase family. (383 aa)
Z518_07398CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (562 aa)
Z518_07593annotation not available (159 aa)
Z518_03702annotation not available (910 aa)
Z518_02931annotation not available (152 aa)
Z518_00163annotation not available (437 aa)
Z518_00741Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (465 aa)
Z518_01176annotation not available (238 aa)
Z518_01447Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (193 aa)
Z518_01734annotation not available (254 aa)
Your Current Organism:
Rhinocladiella mackenziei
NCBI taxonomy Id: 1442369
Other names: R. mackenziei CBS 650.93, Rhinocladiella mackenziei CBS 650.93
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