STRINGSTRING
Z518_10658 Z518_10658 NCS6 NCS6 Z518_01222 Z518_01222 Z518_00450 Z518_00450 Z518_01436 Z518_01436 Z518_10000 Z518_10000 Z518_09870 Z518_09870 Z518_04667 Z518_04667 Z518_06188 Z518_06188 Z518_07509 Z518_07509 Z518_05297 Z518_05297 Z518_07037 Z518_07037 Z518_08797 Z518_08797 Z518_11174 Z518_11174 Z518_09989 Z518_09989 Z518_00493 Z518_00493 NCS2 NCS2 Z518_02819 Z518_02819 Z518_02799 Z518_02799 Z518_02698 Z518_02698 Z518_04027 Z518_04027 Z518_05488 Z518_05488 Z518_07802 Z518_07802 Z518_07596 Z518_07596 ALA1 ALA1 NAT10 NAT10 Z518_05352 Z518_05352 Z518_05205 Z518_05205 Z518_07510 Z518_07510 Z518_08820 Z518_08820 Z518_08604 Z518_08604 Z518_07921 Z518_07921 Z518_09887 Z518_09887 TRM8 TRM8 Z518_06690 Z518_06690 Z518_06684 Z518_06684 Z518_10435 Z518_10435 Z518_10390 Z518_10390
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Z518_10658annotation not available (199 aa)
NCS6Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (418 aa)
Z518_01222Belongs to the class-I aminoacyl-tRNA synthetase family. (633 aa)
Z518_00450annotation not available (1463 aa)
Z518_01436annotation not available (486 aa)
Z518_10000annotation not available (748 aa)
Z518_09870annotation not available (366 aa)
Z518_04667annotation not available (1335 aa)
Z518_06188annotation not available (504 aa)
Z518_07509annotation not available (506 aa)
Z518_05297annotation not available (446 aa)
Z518_07037Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (909 aa)
Z518_08797annotation not available (875 aa)
Z518_11174annotation not available (233 aa)
Z518_09989annotation not available (469 aa)
Z518_00493annotation not available (360 aa)
NCS2Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (356 aa)
Z518_02819annotation not available (281 aa)
Z518_02799annotation not available (250 aa)
Z518_02698Belongs to the CGI121/TPRKB family. (209 aa)
Z518_04027Lysine--tRNA ligase. (624 aa)
Z518_05488Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1324 aa)
Z518_07802annotation not available (503 aa)
Z518_07596annotation not available (560 aa)
ALA1Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (962 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1104 aa)
Z518_05352annotation not available (522 aa)
Z518_05205annotation not available (389 aa)
Z518_07510annotation not available (1121 aa)
Z518_08820Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (1033 aa)
Z518_08604Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (747 aa)
Z518_07921Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (575 aa)
Z518_09887D-aminoacyl-tRNA deacylase. (174 aa)
TRM8tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (294 aa)
Z518_06690Belongs to the class-I aminoacyl-tRNA synthetase family. (1086 aa)
Z518_06684annotation not available (490 aa)
Z518_10435annotation not available (513 aa)
Z518_10390Belongs to the class-I aminoacyl-tRNA synthetase family. (1036 aa)
Your Current Organism:
Rhinocladiella mackenziei
NCBI taxonomy Id: 1442369
Other names: R. mackenziei CBS 650.93, Rhinocladiella mackenziei CBS 650.93
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