104 items (Rhinocladiella mackenziei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Z518_11399	annotation not available (285 aa)
	Z518_11190	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (338 aa)
	Z518_10939	annotation not available (628 aa)
	Z518_10561	annotation not available (646 aa)
	Z518_09253	annotation not available (665 aa)
	Z518_09328	annotation not available (169 aa)
	Z518_08699	Belongs to the AAA ATPase family. (389 aa)
	Z518_06532	annotation not available (2318 aa)
	Z518_07065	annotation not available (299 aa)
	Z518_07250	annotation not available (1630 aa)
	Z518_07515	Endonuclease. (347 aa)
	Z518_05487	annotation not available (1074 aa)
	Z518_05889	annotation not available (410 aa)
	Z518_05939	annotation not available (193 aa)
	Z518_06294	annotation not available (271 aa)
	Z518_03629	annotation not available (480 aa)
	Z518_00831	Histone H2A; Belongs to the histone H2A family. (139 aa)
	Z518_01583	annotation not available (658 aa)
	Z518_01231	annotation not available (880 aa)
	Z518_01216	annotation not available (1388 aa)
	Z518_00996	annotation not available (841 aa)
	Z518_03739	annotation not available (617 aa)
	Z518_03784	annotation not available (695 aa)
	Z518_04303	annotation not available (232 aa)
	Z518_02010	annotation not available (452 aa)
	Z518_02651	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (605 aa)
	Z518_00180	annotation not available (414 aa)
	Z518_01098	annotation not available (917 aa)
	Z518_01283	annotation not available (477 aa)
	Z518_11400	annotation not available (109 aa)
	Z518_10265	Belongs to the RNR ribonuclease family. (1005 aa)
	Z518_10487	annotation not available (507 aa)
	Z518_10668	annotation not available (50 aa)
	Z518_10204	Belongs to the DEAD box helicase family. (509 aa)
	Z518_08082	Belongs to the RNase T2 family. (321 aa)
	Z518_07737	annotation not available (1326 aa)
	Z518_05150	annotation not available (364 aa)
	Z518_05326	Belongs to the cullin family. (898 aa)
	LSM4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (119 aa)
	Z518_06360	annotation not available (1148 aa)
	Z518_02281	annotation not available (821 aa)
	Z518_03074	Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (208 aa)
	Z518_03405	annotation not available (514 aa)
	Z518_00216	annotation not available (369 aa)
	Z518_01124	annotation not available (312 aa)
	Z518_01455	annotation not available (500 aa)
	Z518_09954	Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (416 aa)
	Z518_11194	annotation not available (514 aa)
	Z518_11214	annotation not available (1075 aa)
	Z518_10858	annotation not available (830 aa)
	Z518_10395	annotation not available (418 aa)
	Z518_06539	annotation not available (163 aa)
	Z518_09821	annotation not available (507 aa)
	Z518_09891	annotation not available (631 aa)
	Z518_09916	annotation not available (263 aa)
	Z518_09991	annotation not available (1414 aa)
	Z518_10052	annotation not available (352 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1178 aa)
	Z518_09137	annotation not available (392 aa)
	Z518_07602	annotation not available (360 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (428 aa)
	Z518_07895	annotation not available (298 aa)
	Z518_05409	annotation not available (652 aa)
	Z518_08287	annotation not available (715 aa)
	Z518_05825	annotation not available (245 aa)
	Z518_05876	annotation not available (260 aa)
	Z518_05906	annotation not available (1372 aa)
	Z518_08799	Belongs to the DEAD box helicase family. (525 aa)
	Z518_06331	annotation not available (264 aa)
	Z518_06406	annotation not available (618 aa)
	Z518_04284	annotation not available (1302 aa)
	Z518_07454	Nuclear cap-binding protein subunit 2. (178 aa)
	Z518_07499	annotation not available (789 aa)
	Z518_07690	annotation not available (1255 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. (189 aa)
	Z518_02965	annotation not available (283 aa)
	Z518_03628	annotation not available (200 aa)
	Z518_03115	annotation not available (762 aa)
	Z518_03728	annotation not available (246 aa)
	Z518_03291	annotation not available (818 aa)
	Z518_11407	annotation not available (1482 aa)
	Z518_00453	annotation not available (837 aa)
	Z518_10404	Belongs to the eukaryotic initiation factor 4E family. (226 aa)
	Z518_01839	Belongs to the RNase T2 family. (463 aa)
	Z518_01456	annotation not available (673 aa)
	Z518_02395	annotation not available (135 aa)
	Z518_09321	annotation not available (152 aa)
	Z518_03378	annotation not available (205 aa)
	Z518_00184	annotation not available (748 aa)
	Z518_08652	annotation not available (747 aa)
	Z518_00727	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1394 aa)
	Z518_00832	annotation not available (609 aa)
	Z518_06686	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1043 aa)
	Z518_07063	annotation not available (432 aa)
	Z518_07338	annotation not available (291 aa)
	Z518_01574	annotation not available (835 aa)
	Z518_07568	annotation not available (216 aa)
	Z518_04486	annotation not available (1150 aa)
	PAN3	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...] (652 aa)
	Z518_02781	annotation not available (405 aa)
	Z518_02851	annotation not available (258 aa)
	Z518_02946	annotation not available (893 aa)
	Z518_03136	annotation not available (480 aa)
	Z518_00550	annotation not available (1081 aa)

Your Current Organism:

Rhinocladiella mackenziei

NCBI taxonomy Id: 1442369
Other names: R. mackenziei CBS 650.93, Rhinocladiella mackenziei CBS 650.93

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FEN1	Z518_03405	A0A0D2IE64	A0A0D2HDW0	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	annotation not available	0.830
FEN1	Z518_04303	A0A0D2IE64	A0A0D2FVZ5	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	annotation not available	0.521
FEN1	Z518_05326	A0A0D2IE64	A0A0D2H221	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Belongs to the cullin family.	0.650
FEN1	Z518_05939	A0A0D2IE64	A0A0D2FSH7	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	annotation not available	0.521
FEN1	Z518_06294	A0A0D2IE64	A0A0D2FTK8	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	annotation not available	0.425
FEN1	Z518_07063	A0A0D2IE64	A0A0D2J3J9	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	annotation not available	0.557
FEN1	Z518_07515	A0A0D2IE64	A0A0D2FPA7	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Endonuclease.	0.674
FEN1	Z518_10487	A0A0D2IE64	A0A0D2GPR0	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	annotation not available	0.975
FEN1	Z518_11190	A0A0D2IE64	A0A0D2FBI4	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.752
FEN1	Z518_11194	A0A0D2IE64	A0A0D2I891	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	annotation not available	0.526
LSM1	LSM4	A0A0D2IQL1	A0A0D2H4J5	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.976
LSM1	Z518_00727	A0A0D2IQL1	A0A0D2J1S8	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	0.926
LSM1	Z518_01124	A0A0D2IQL1	A0A0D2HHE0	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	annotation not available	0.813
LSM1	Z518_01583	A0A0D2IQL1	A0A0D2JM40	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	annotation not available	0.482
LSM1	Z518_02395	A0A0D2IQL1	A0A0D2IWK1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	annotation not available	0.973
LSM1	Z518_02946	A0A0D2IQL1	A0A0D2JG30	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	annotation not available	0.896
LSM1	Z518_03291	A0A0D2IQL1	A0A0D2IRM2	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	annotation not available	0.969
LSM1	Z518_06539	A0A0D2IQL1	A0A0D2IAZ2	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	annotation not available	0.815
LSM1	Z518_07690	A0A0D2IQL1	A0A0D2ILS0	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	annotation not available	0.555
LSM1	Z518_08652	A0A0D2IQL1	A0A0D2J1D4	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	annotation not available	0.413