(15 nodes) Histone-lysine N-methyltransferase activity network (Rhinocladiella mackenziei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Z518_10456	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1270 aa)
	Z518_02918	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (539 aa)
	Z518_10845	annotation not available (432 aa)
	Z518_10587	annotation not available (1397 aa)
	Z518_08690	Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (983 aa)
	Z518_00543	annotation not available (388 aa)
	Z518_01304	annotation not available (175 aa)
	Z518_07217	annotation not available (782 aa)
	Z518_06431	annotation not available (858 aa)
	Z518_01912	annotation not available (763 aa)
	Z518_04357	annotation not available (529 aa)
	Z518_09557	annotation not available (192 aa)
	Z518_03338	annotation not available (417 aa)
	Z518_07388	annotation not available (87 aa)
	Z518_02700	annotation not available (473 aa)

Your Current Organism:

Rhinocladiella mackenziei

NCBI taxonomy Id: 1442369
Other names: R. mackenziei CBS 650.93, Rhinocladiella mackenziei CBS 650.93

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Z518_00543	Z518_01912	A0A0D2HFK8	A0A0D2IN56	annotation not available	annotation not available	0.553
Z518_00543	Z518_02700	A0A0D2HFK8	A0A0D2JFK9	annotation not available	annotation not available	0.753
Z518_00543	Z518_02918	A0A0D2HFK8	A0A0D2G140	annotation not available	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.706
Z518_00543	Z518_06431	A0A0D2HFK8	A0A0D2IIJ9	annotation not available	annotation not available	0.452
Z518_00543	Z518_07217	A0A0D2HFK8	A0A0D2ICS8	annotation not available	annotation not available	0.549
Z518_00543	Z518_08690	A0A0D2HFK8	A0A0D2GWZ2	annotation not available	Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.606
Z518_00543	Z518_10456	A0A0D2HFK8	A0A0D2FE04	annotation not available	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	0.723
Z518_00543	Z518_10587	A0A0D2HFK8	A0A0D2GQ59	annotation not available	annotation not available	0.545
Z518_01912	Z518_00543	A0A0D2IN56	A0A0D2HFK8	annotation not available	annotation not available	0.553
Z518_01912	Z518_02700	A0A0D2IN56	A0A0D2JFK9	annotation not available	annotation not available	0.778
Z518_01912	Z518_02918	A0A0D2IN56	A0A0D2G140	annotation not available	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.877
Z518_01912	Z518_03338	A0A0D2IN56	A0A0D2IZ52	annotation not available	annotation not available	0.553
Z518_01912	Z518_04357	A0A0D2IN56	A0A0D2IT76	annotation not available	annotation not available	0.779
Z518_01912	Z518_06431	A0A0D2IN56	A0A0D2IIJ9	annotation not available	annotation not available	0.616
Z518_01912	Z518_07217	A0A0D2IN56	A0A0D2ICS8	annotation not available	annotation not available	0.865
Z518_01912	Z518_07388	A0A0D2IN56	A0A0D2J496	annotation not available	annotation not available	0.553
Z518_01912	Z518_08690	A0A0D2IN56	A0A0D2GWZ2	annotation not available	Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.943
Z518_01912	Z518_10456	A0A0D2IN56	A0A0D2FE04	annotation not available	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	0.805
Z518_01912	Z518_10587	A0A0D2IN56	A0A0D2GQ59	annotation not available	annotation not available	0.820
Z518_01912	Z518_10845	A0A0D2IN56	A0A0D2GNH6	annotation not available	annotation not available	0.553