(19 nodes) RNA polymerase II preinitiation complex assembly network (Rhinocladiella mackenziei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Z518_07072	annotation not available (365 aa)
	Z518_08138	annotation not available (560 aa)
	Z518_10911	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (238 aa)
	Z518_09154	annotation not available (305 aa)
	Z518_09918	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (692 aa)
	Z518_00718	annotation not available (450 aa)
	Z518_07155	annotation not available (1108 aa)
	Z518_08719	annotation not available (160 aa)
	Z518_09007	annotation not available (662 aa)
	Z518_01205	annotation not available (214 aa)
	Z518_00850	annotation not available (354 aa)
	Z518_02563	annotation not available (337 aa)
	Z518_02092	annotation not available (92 aa)
	Z518_06490	annotation not available (264 aa)
	Z518_04505	annotation not available (670 aa)
	Z518_05292	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (111 aa)
	Z518_09337	annotation not available (818 aa)
	Z518_05872	annotation not available (379 aa)
	Z518_05293	annotation not available (345 aa)

Your Current Organism:

Rhinocladiella mackenziei

NCBI taxonomy Id: 1442369
Other names: R. mackenziei CBS 650.93, Rhinocladiella mackenziei CBS 650.93

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Z518_00718	Z518_00850	A0A0D2G4L1	A0A0D2IUK7	annotation not available	annotation not available	0.981
Z518_00718	Z518_01205	A0A0D2G4L1	A0A0D2IVQ6	annotation not available	annotation not available	0.999
Z518_00718	Z518_05292	A0A0D2G4L1	A0A0D2IF34	annotation not available	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.850
Z518_00718	Z518_05293	A0A0D2G4L1	A0A0D2J5U8	annotation not available	annotation not available	0.850
Z518_00718	Z518_05872	A0A0D2G4L1	A0A0D2J7J9	annotation not available	annotation not available	0.913
Z518_00718	Z518_06490	A0A0D2G4L1	A0A0D2J217	annotation not available	annotation not available	0.999
Z518_00718	Z518_07072	A0A0D2G4L1	A0A0D2ICH7	annotation not available	annotation not available	0.938
Z518_00718	Z518_07155	A0A0D2G4L1	A0A0D2FNH7	annotation not available	annotation not available	0.999
Z518_00718	Z518_08138	A0A0D2G4L1	A0A0D2I8L4	annotation not available	annotation not available	0.999
Z518_00718	Z518_09007	A0A0D2G4L1	A0A0D2FGX2	annotation not available	annotation not available	0.999
Z518_00718	Z518_09154	A0A0D2G4L1	A0A0D2GSU5	annotation not available	annotation not available	0.846
Z518_00718	Z518_09337	A0A0D2G4L1	A0A0D2IEE0	annotation not available	annotation not available	0.972
Z518_00718	Z518_09918	A0A0D2G4L1	A0A0D2GRA3	annotation not available	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.660
Z518_00718	Z518_10911	A0A0D2G4L1	A0A0D2I2M7	annotation not available	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...]	0.999
Z518_00850	Z518_00718	A0A0D2IUK7	A0A0D2G4L1	annotation not available	annotation not available	0.981
Z518_00850	Z518_01205	A0A0D2IUK7	A0A0D2IVQ6	annotation not available	annotation not available	0.972
Z518_00850	Z518_05292	A0A0D2IUK7	A0A0D2IF34	annotation not available	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.885
Z518_00850	Z518_05293	A0A0D2IUK7	A0A0D2J5U8	annotation not available	annotation not available	0.885
Z518_00850	Z518_05872	A0A0D2IUK7	A0A0D2J7J9	annotation not available	annotation not available	0.876
Z518_00850	Z518_06490	A0A0D2IUK7	A0A0D2J217	annotation not available	annotation not available	0.971