STRINGSTRING
Z518_03359 Z518_03359 Z518_04942 Z518_04942 Z518_04861 Z518_04861 Z518_04205 Z518_04205 Z518_05892 Z518_05892 Z518_05816 Z518_05816 Z518_07694 Z518_07694 Z518_01604 Z518_01604 Z518_07253 Z518_07253 Z518_00169 Z518_00169 Z518_03217 Z518_03217 Z518_03107 Z518_03107 Z518_02877 Z518_02877 Z518_09055 Z518_09055 Z518_01658 Z518_01658 Z518_01386 Z518_01386 Z518_03330 Z518_03330 Z518_01642 Z518_01642 Z518_10070 Z518_10070 Z518_04642 Z518_04642 Z518_00237 Z518_00237 Z518_04246 Z518_04246 Z518_06383 Z518_06383 Z518_06118 Z518_06118 Z518_06018 Z518_06018 Z518_01932 Z518_01932 Z518_07790 Z518_07790 Z518_07659 Z518_07659 Z518_07921 Z518_07921 Z518_03888 Z518_03888 Z518_06918 Z518_06918 Z518_06226 Z518_06226 Z518_05861 Z518_05861 Z518_08205 Z518_08205 Z518_09467 Z518_09467 Z518_09831 Z518_09831 Z518_06725 Z518_06725 Z518_10515 Z518_10515 Z518_08153 Z518_08153 Z518_08053 Z518_08053 Z518_08003 Z518_08003 Z518_03049 Z518_03049 Z518_02362 Z518_02362 Z518_04569 Z518_04569 DRE2 DRE2 Z518_07101 Z518_07101 Z518_08344 Z518_08344 Z518_08212 Z518_08212 Z518_09264 Z518_09264 Z518_09179 Z518_09179 Z518_09053 Z518_09053 Z518_10019 Z518_10019 Z518_09848 Z518_09848 Z518_11035 Z518_11035 CFD1 CFD1 Z518_00808 Z518_00808 Z518_00708 Z518_00708 Z518_00361 Z518_00361 Z518_09034 Z518_09034 Z518_07285 Z518_07285 Z518_07691 Z518_07691 Z518_05527 Z518_05527 Z518_05577 Z518_05577 Z518_05854 Z518_05854 NTH1 NTH1 Z518_04308 Z518_04308 Z518_04933 Z518_04933 NBP35 NBP35
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Z518_03359annotation not available (224 aa)
Z518_049422-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily. (569 aa)
Z518_04861annotation not available (602 aa)
Z518_04205annotation not available (826 aa)
Z518_05892Belongs to the NARF family. (616 aa)
Z518_05816Belongs to the complex I 20 kDa subunit family. (230 aa)
Z518_07694annotation not available (1116 aa)
Z518_01604Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (804 aa)
Z518_07253annotation not available (636 aa)
Z518_00169annotation not available (220 aa)
Z518_03217DNA polymerase. (1107 aa)
Z518_03107Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (249 aa)
Z518_02877annotation not available (777 aa)
Z518_09055annotation not available (141 aa)
Z518_01658annotation not available (653 aa)
Z518_01386annotation not available (555 aa)
Z518_03330annotation not available (655 aa)
Z518_01642annotation not available (440 aa)
Z518_10070annotation not available (228 aa)
Z518_04642annotation not available (1000 aa)
Z518_00237annotation not available (143 aa)
Z518_04246annotation not available (1438 aa)
Z518_06383annotation not available (508 aa)
Z518_06118annotation not available (250 aa)
Z518_06018DNA polymerase. (1733 aa)
Z518_01932annotation not available (852 aa)
Z518_07790annotation not available (270 aa)
Z518_076592-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (439 aa)
Z518_07921Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (575 aa)
Z518_03888annotation not available (270 aa)
Z518_06918annotation not available (616 aa)
Z518_06226annotation not available (582 aa)
Z518_05861annotation not available (288 aa)
Z518_08205annotation not available (286 aa)
Z518_09467Belongs to the complex I 49 kDa subunit family. (472 aa)
Z518_09831Belongs to the BolA/IbaG family. (103 aa)
Z518_06725Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (631 aa)
Z518_10515Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (296 aa)
Z518_08153DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2240 aa)
Z518_08053NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (505 aa)
Z518_08003Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (422 aa)
Z518_03049annotation not available (1553 aa)
Z518_02362annotation not available (645 aa)
Z518_04569annotation not available (401 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (327 aa)
Z518_07101annotation not available (807 aa)
Z518_08344annotation not available (215 aa)
Z518_082123-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (773 aa)
Z518_09264DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (519 aa)
Z518_09179annotation not available (832 aa)
Z518_09053annotation not available (312 aa)
Z518_10019Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (733 aa)
Z518_09848Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (202 aa)
Z518_11035annotation not available (605 aa)
CFD1Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (334 aa)
Z518_00808annotation not available (2152 aa)
Z518_00708annotation not available (613 aa)
Z518_00361Belongs to the complex I 75 kDa subunit family. (822 aa)
Z518_09034annotation not available (1054 aa)
Z518_07285annotation not available (321 aa)
Z518_07691annotation not available (313 aa)
Z518_05527Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (808 aa)
Z518_05577annotation not available (186 aa)
Z518_05854annotation not available (1692 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (434 aa)
Z518_04308annotation not available (1359 aa)
Z518_04933annotation not available (324 aa)
NBP35Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (342 aa)
Your Current Organism:
Rhinocladiella mackenziei
NCBI taxonomy Id: 1442369
Other names: R. mackenziei CBS 650.93, Rhinocladiella mackenziei CBS 650.93
Server load: medium (48%) [HD]