57 items (Rhinocladiella mackenziei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Z518_09238	Belongs to the AAA ATPase family. (439 aa)
	Z518_09328	annotation not available (169 aa)
	Z518_08699	Belongs to the AAA ATPase family. (389 aa)
	Z518_07305	DNA ligase. (870 aa)
	Z518_07310	mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate; Belongs to the eukaryotic GTase family. (420 aa)
	Z518_04267	annotation not available (367 aa)
	Z518_03018	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (613 aa)
	Z518_10265	Belongs to the RNR ribonuclease family. (1005 aa)
	Z518_10593	Belongs to the universal ribosomal protein uS17 family. (162 aa)
	Z518_09728	annotation not available (84 aa)
	Z518_10084	annotation not available (1089 aa)
	Z518_07326	annotation not available (582 aa)
	Z518_07436	DNA helicase; Belongs to the MCM family. (1007 aa)
	Z518_05206	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (143 aa)
	Z518_04027	Lysine--tRNA ligase. (624 aa)
	Z518_00914	annotation not available (1225 aa)
	Z518_10996	annotation not available (142 aa)
	Z518_10604	Belongs to the AAA ATPase family. (393 aa)
	Z518_09779	Belongs to the AAA ATPase family. (389 aa)
	Z518_11128	annotation not available (549 aa)
	Z518_10012	annotation not available (140 aa)
	Z518_10052	annotation not available (352 aa)
	Z518_07572	Eukaryotic translation initiation factor 5A. (160 aa)
	Z518_09372	annotation not available (213 aa)
	Z518_05297	annotation not available (446 aa)
	Z518_05327	annotation not available (131 aa)
	Z518_05825	annotation not available (245 aa)
	Z518_05906	annotation not available (1372 aa)
	Z518_07064	annotation not available (791 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (814 aa)
	Z518_02709	annotation not available (1079 aa)
	Z518_02985	annotation not available (649 aa)
	Z518_03703	DNA helicase; Belongs to the MCM family. (863 aa)
	Z518_03225	DNA ligase. (1031 aa)
	Z518_11032	annotation not available (404 aa)
	Z518_04060	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (609 aa)
	Z518_00705	DNA helicase; Belongs to the MCM family. (726 aa)
	Z518_01115	annotation not available (147 aa)
	Z518_02279	annotation not available (147 aa)
	Z518_09487	annotation not available (951 aa)
	Z518_03227	annotation not available (1792 aa)
	Z518_03293	Belongs to the universal ribosomal protein uS12 family. (178 aa)
	Z518_03378	annotation not available (205 aa)
	Z518_00531	Belongs to the AAA ATPase family. (456 aa)
	Z518_06696	Belongs to the AAA ATPase family. (461 aa)
	Z518_01217	DNA helicase; Belongs to the MCM family. (956 aa)
	Z518_07704	annotation not available (313 aa)
	Z518_06087	DNA helicase; Belongs to the MCM family. (903 aa)
	Z518_05057	annotation not available (66 aa)
	Z518_02519	DNA ligase. (886 aa)
	Z518_03116	annotation not available (1225 aa)
	Z518_03201	annotation not available (278 aa)
	Z518_00580	annotation not available (435 aa)
	Z518_01146	Belongs to the universal ribosomal protein uS12 family. (146 aa)
	Z518_01618	annotation not available (254 aa)
	Z518_01739	Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (149 aa)
	Z518_10689	annotation not available (312 aa)

Your Current Organism:

Rhinocladiella mackenziei

NCBI taxonomy Id: 1442369
Other names: R. mackenziei CBS 650.93, Rhinocladiella mackenziei CBS 650.93

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	Z518_00705	A0A0D2IMR7	A0A0D2IU86	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	Z518_01217	A0A0D2IMR7	A0A0D2J384	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	Z518_02519	A0A0D2IMR7	A0A0D2JF68	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA ligase.	0.766
MCM7	Z518_03201	A0A0D2IMR7	A0A0D2JGV3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	annotation not available	0.843
MCM7	Z518_03225	A0A0D2IMR7	A0A0D2IRH8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA ligase.	0.482
MCM7	Z518_03703	A0A0D2IMR7	A0A0D2IRE4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	Z518_04060	A0A0D2IMR7	A0A0D2ISH4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.860
MCM7	Z518_06087	A0A0D2IMR7	A0A0D2J828	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	Z518_07064	A0A0D2IMR7	A0A0D2IJX7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	annotation not available	0.996
MCM7	Z518_07305	A0A0D2IMR7	A0A0D2FNT4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA ligase.	0.828
MCM7	Z518_07436	A0A0D2IMR7	A0A0D2H0D3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	Z518_10689	A0A0D2IMR7	A0A0D2FCC7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	annotation not available	0.793
Z518_00531	Z518_01618	A0A0D2J193	A0A0D2JM72	Belongs to the AAA ATPase family.	annotation not available	0.627
Z518_00531	Z518_06696	A0A0D2J193	A0A0D2J2J0	Belongs to the AAA ATPase family.	Belongs to the AAA ATPase family.	0.999
Z518_00531	Z518_07704	A0A0D2J193	A0A0D2J567	Belongs to the AAA ATPase family.	annotation not available	0.418
Z518_00531	Z518_08699	A0A0D2J193	A0A0D2FLA8	Belongs to the AAA ATPase family.	Belongs to the AAA ATPase family.	0.999
Z518_00531	Z518_09238	A0A0D2J193	A0A0D2FHU1	Belongs to the AAA ATPase family.	Belongs to the AAA ATPase family.	0.999
Z518_00531	Z518_09779	A0A0D2J193	A0A0D2I4I9	Belongs to the AAA ATPase family.	Belongs to the AAA ATPase family.	0.999
Z518_00531	Z518_10593	A0A0D2J193	A0A0D2GQ65	Belongs to the AAA ATPase family.	Belongs to the universal ribosomal protein uS17 family.	0.446
Z518_00531	Z518_10604	A0A0D2J193	A0A0D2I3X1	Belongs to the AAA ATPase family.	Belongs to the AAA ATPase family.	0.999