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YTM1 YTM1 TIF6 TIF6 ERB1 ERB1 Z518_01810 Z518_01810 Z518_03344 Z518_03344 Z518_01193 Z518_01193 Z518_08142 Z518_08142 Z518_08434 Z518_08434 NOP7 NOP7 Z518_05040 Z518_05040 Z518_09476 Z518_09476 Z518_05156 Z518_05156 Z518_03807 Z518_03807 Z518_05546 Z518_05546 Z518_03200 Z518_03200 Z518_04802 Z518_04802 TSR3 TSR3 Z518_01688 Z518_01688 Z518_08371 Z518_08371 Z518_03808 Z518_03808 SPB1 SPB1 Z518_01447 Z518_01447
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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YTM1Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (460 aa)
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (248 aa)
ERB1Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (781 aa)
Z518_01810U3 small nucleolar RNA-associated protein 22. (1149 aa)
Z518_03344Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (249 aa)
Z518_01193U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2. (743 aa)
Z518_08142KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (340 aa)
Z518_08434Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (743 aa)
NOP7Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (699 aa)
Z518_05040Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (238 aa)
Z518_09476rRNA-processing protein; Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit. Belongs to the CGR1 family. (131 aa)
Z518_05156Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (429 aa)
Z518_0380760S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (188 aa)
Z518_05546U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (737 aa)
Z518_03200ATP-dependent RNA helicase DBP10. (932 aa)
Z518_04802H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (233 aa)
TSR3Ribosome biogenesis protein TSR3; Ribosome biogenesis protein required for processing 35S pre- rRNA at site D; Belongs to the TSR3 family. (392 aa)
Z518_01688annotation not available (295 aa)
Z518_08371Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (659 aa)
Z518_03808Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (685 aa)
SPB1AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (825 aa)
Z518_01447Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (193 aa)
Your Current Organism:
Rhinocladiella mackenziei
NCBI taxonomy Id: 1442369
Other names: R. mackenziei CBS 650.93, Rhinocladiella mackenziei CBS 650.93
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