(34 nodes) Mixed, incl. Class II aldolase/adducin N-terminal, and Acyl-coenzyme A thioesterase 13 network (Fonsecaea multimorphosa)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	Z520_10783	Zn(2)-C6 fungal-type domain-containing protein. (410 aa)
	Z520_09440	Nudix hydrolase domain-containing protein. (213 aa)
	MDE1	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (238 aa)
	Z520_06048	Zn(2)-C6 fungal-type domain-containing protein. (394 aa)
	Z520_00267	Uncharacterized protein. (284 aa)
	Z520_08464	4HBT domain-containing protein. (155 aa)
	Z520_04392	Aldolase_II domain-containing protein. (303 aa)
	Z520_02390	Aldolase_II domain-containing protein. (300 aa)
	Z520_02561	Uncharacterized protein. (358 aa)
	Z520_02581	Zn(2)-C6 fungal-type domain-containing protein. (756 aa)
	Z520_12108	Fungal_trans domain-containing protein. (631 aa)
	Z520_10853	Aldolase_II domain-containing protein. (285 aa)
	Z520_10530	Uncharacterized protein. (333 aa)
	Z520_07433	4HBT domain-containing protein. (183 aa)
	Z520_04518	Aldolase_II domain-containing protein. (333 aa)
	Z520_07238	4HBT domain-containing protein. (192 aa)
	Z520_06936	Goodbye domain-containing protein. (1564 aa)
	Z520_06627	Uncharacterized protein. (291 aa)
	Z520_02835	Aldolase_II domain-containing protein. (316 aa)
	Z520_11793	Aldolase_II domain-containing protein. (289 aa)
	Z520_05055	SCP domain-containing protein; Belongs to the CRISP family. (301 aa)
	Z520_10250	Aldolase_II domain-containing protein. (296 aa)
	Z520_02657	Aldolase_II domain-containing protein. (284 aa)
	Z520_09408	4HBT domain-containing protein. (175 aa)
	Z520_00830	Uncharacterized protein. (276 aa)
	Z520_09109	Aldolase_II domain-containing protein. (282 aa)
	Z520_09160	Aldolase_II domain-containing protein. (268 aa)
	Z520_08728	Uncharacterized protein. (331 aa)
	Z520_00266	Uncharacterized protein. (314 aa)
	ADI1	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (176 aa)
	MRI1	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (395 aa)
	Z520_05179	Endo/exonuclease/phosphatase domain-containing protein. (335 aa)
	Z520_01009	4HBT domain-containing protein. (169 aa)
	Z520_01666	Aldolase_II domain-containing protein. (85 aa)

Your Current Organism:

Fonsecaea multimorphosa

NCBI taxonomy Id: 1442371
Other names: F. multimorphosa CBS 102226, Fonsecaea multimorphosa CBS 102226

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADI1	MDE1	A0A0D2KK78	A0A0D2H5U6	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).	0.980
ADI1	MRI1	A0A0D2KK78	A0A0D2KLW7	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	0.796
ADI1	Z520_00266	A0A0D2KK78	A0A0D2KJA4	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Uncharacterized protein.	0.693
ADI1	Z520_00830	A0A0D2KK78	A0A0D2KDE3	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Uncharacterized protein.	0.972
ADI1	Z520_01666	A0A0D2KK78	A0A0D2L2B5	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aldolase_II domain-containing protein.	0.696
ADI1	Z520_02390	A0A0D2KK78	A0A0D2IYY3	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aldolase_II domain-containing protein.	0.696
ADI1	Z520_02657	A0A0D2KK78	A0A0D2KD25	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aldolase_II domain-containing protein.	0.696
ADI1	Z520_02835	A0A0D2KK78	A0A0D2K635	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aldolase_II domain-containing protein.	0.696
ADI1	Z520_04392	A0A0D2KK78	A0A0D2IRX9	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aldolase_II domain-containing protein.	0.696
ADI1	Z520_04518	A0A0D2KK78	A0A0D2K211	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aldolase_II domain-containing protein.	0.696
ADI1	Z520_06048	A0A0D2KK78	A0A0D2H812	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Zn(2)-C6 fungal-type domain-containing protein.	0.693
ADI1	Z520_06627	A0A0D2KK78	A0A0D2K3U7	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Uncharacterized protein.	0.935
ADI1	Z520_09109	A0A0D2KK78	A0A0D2KER9	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aldolase_II domain-containing protein.	0.693
ADI1	Z520_09160	A0A0D2KK78	A0A0D2KEW7	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aldolase_II domain-containing protein.	0.696
ADI1	Z520_10250	A0A0D2KK78	A0A0D2KBF2	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aldolase_II domain-containing protein.	0.696
ADI1	Z520_10530	A0A0D2KK78	A0A0D2JSZ9	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Uncharacterized protein.	0.972
ADI1	Z520_10783	A0A0D2KK78	A0A0D2GVH7	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Zn(2)-C6 fungal-type domain-containing protein.	0.693
ADI1	Z520_10853	A0A0D2KK78	A0A0D2JSN4	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aldolase_II domain-containing protein.	0.696
ADI1	Z520_11793	A0A0D2KK78	A0A0D2K848	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aldolase_II domain-containing protein.	0.693
MDE1	ADI1	A0A0D2H5U6	A0A0D2KK78	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	0.980