23 items (Fonsecaea multimorphosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Z520_11069	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1762 aa)
	Z520_10161	Uncharacterized protein. (1025 aa)
	Z520_03361	CDC73_C domain-containing protein. (445 aa)
	Z520_01081	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1422 aa)
	Z520_11065	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1258 aa)
	Z520_08281	RNA_pol_L_2 domain-containing protein. (270 aa)
	Z520_06399	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (582 aa)
	Z520_06246	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (119 aa)
	Z520_00323	S1 domain-containing protein. (169 aa)
	Z520_10219	TFIIS N-terminal domain-containing protein. (397 aa)
	Z520_07950	Uncharacterized protein. (155 aa)
	Z520_07547	Uncharacterized protein. (1235 aa)
	Z520_07091	Uncharacterized protein. (497 aa)
	Z520_05808	RPOL9 domain-containing protein. (111 aa)
	Z520_05353	RPOL4c domain-containing protein. (152 aa)
	Z520_00304	Uncharacterized protein. (308 aa)
	Z520_01175	Plus3 domain-containing protein. (616 aa)
	Z520_08363	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1118 aa)
	Z520_00556	RPOLD domain-containing protein. (338 aa)
	Z520_05314	Uncharacterized protein. (153 aa)
	Z520_04298	Uncharacterized protein. (239 aa)
	Z520_03212	Uncharacterized protein. (549 aa)
	Z520_01194	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (853 aa)

Your Current Organism:

Fonsecaea multimorphosa

NCBI taxonomy Id: 1442371
Other names: F. multimorphosa CBS 102226, Fonsecaea multimorphosa CBS 102226

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Z520_00304	Z520_00323	A0A0D2KBX8	A0A0D2J2G5	Uncharacterized protein.	S1 domain-containing protein.	0.983
Z520_00304	Z520_00556	A0A0D2KBX8	A0A0D2KK84	Uncharacterized protein.	RPOLD domain-containing protein.	0.992
Z520_00304	Z520_01081	A0A0D2KBX8	A0A0D2HL22	Uncharacterized protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.996
Z520_00304	Z520_01175	A0A0D2KBX8	A0A0D2KGV7	Uncharacterized protein.	Plus3 domain-containing protein.	0.879
Z520_00304	Z520_01194	A0A0D2KBX8	A0A0D2L116	Uncharacterized protein.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.990
Z520_00304	Z520_03212	A0A0D2KBX8	A0A0D2KUX1	Uncharacterized protein.	Uncharacterized protein.	0.893
Z520_00304	Z520_03361	A0A0D2KBX8	A0A0D2HFH9	Uncharacterized protein.	CDC73_C domain-containing protein.	0.924
Z520_00304	Z520_04298	A0A0D2KBX8	A0A0D2KSG7	Uncharacterized protein.	Uncharacterized protein.	0.994
Z520_00304	Z520_05314	A0A0D2KBX8	A0A0D2KQ71	Uncharacterized protein.	Uncharacterized protein.	0.987
Z520_00304	Z520_05353	A0A0D2KBX8	A0A0D2JZG1	Uncharacterized protein.	RPOL4c domain-containing protein.	0.990
Z520_00304	Z520_05808	A0A0D2KBX8	A0A0D2JYA0	Uncharacterized protein.	RPOL9 domain-containing protein.	0.994
Z520_00304	Z520_06246	A0A0D2KBX8	A0A0D2IMA9	Uncharacterized protein.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.983
Z520_00304	Z520_06399	A0A0D2KBX8	A0A0D2IKS9	Uncharacterized protein.	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	0.862
Z520_00304	Z520_07091	A0A0D2KBX8	A0A0D2JU13	Uncharacterized protein.	Uncharacterized protein.	0.994
Z520_00304	Z520_07547	A0A0D2KBX8	A0A0D2JTK6	Uncharacterized protein.	Uncharacterized protein.	0.802
Z520_00304	Z520_07950	A0A0D2KBX8	A0A0D2JRU2	Uncharacterized protein.	Uncharacterized protein.	0.973
Z520_00304	Z520_08281	A0A0D2KBX8	A0A0D2IG41	Uncharacterized protein.	RNA_pol_L_2 domain-containing protein.	0.990
Z520_00304	Z520_08363	A0A0D2KBX8	A0A0D2KHF0	Uncharacterized protein.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.983
Z520_00304	Z520_10161	A0A0D2KBX8	A0A0D2GX02	Uncharacterized protein.	Uncharacterized protein.	0.934
Z520_00304	Z520_10219	A0A0D2KBX8	A0A0D2JLJ9	Uncharacterized protein.	TFIIS N-terminal domain-containing protein.	0.994