64 items (Fonsecaea multimorphosa) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	Z520_11049	Uncharacterized protein. (618 aa)
	Z520_00478	Nudix hydrolase domain-containing protein. (894 aa)
	Z520_00323	S1 domain-containing protein. (169 aa)
	Z520_00263	Uncharacterized protein. (306 aa)
	INT6	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (503 aa)
	Z520_01569	NTP_transf_9 domain-containing protein. (262 aa)
	Z520_00962	HRDC domain-containing protein. (859 aa)
	Z520_02606	ANK_REP_REGION domain-containing protein. (1962 aa)
	Z520_02545	WD_REPEATS_REGION domain-containing protein. (616 aa)
	PAN3	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...] (652 aa)
	Z520_04912	RBR-type E3 ubiquitin transferase. (745 aa)
	Z520_04902	PUM-HD domain-containing protein. (814 aa)
	Z520_06281	Uncharacterized protein. (328 aa)
	Z520_07070	Zn(2)-C6 fungal-type domain-containing protein. (689 aa)
	Z520_07647	TYR_PHOSPHATASE_2 domain-containing protein. (656 aa)
	Z520_10516	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (421 aa)
	Z520_10416	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (393 aa)
	Z520_11929	BHLH domain-containing protein. (331 aa)
	Z520_00738	PAT1 domain-containing protein. (817 aa)
	Z520_01829	Uncharacterized protein. (347 aa)
	Z520_03562	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (389 aa)
	Z520_04542	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (439 aa)
	Z520_06260	PUM-HD domain-containing protein. (890 aa)
	Z520_07831	PAP-associated domain-containing protein. (1349 aa)
	Z520_09666	Fe2OG dioxygenase domain-containing protein. (699 aa)
	Z520_10121	PUM-HD domain-containing protein. (996 aa)
	Z520_00488	Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (365 aa)
	Z520_11283	Guanine nucleotide-binding protein subunit beta-like protein. (316 aa)
	Z520_11770	Zn(2)-C6 fungal-type domain-containing protein. (656 aa)
	Z520_00505	Tr-type G domain-containing protein. (642 aa)
	Z520_00080	Uncharacterized protein. (2119 aa)
	Z520_03232	Uncharacterized protein. (518 aa)
	Z520_04719	Uncharacterized protein. (608 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1187 aa)
	Z520_06041	Uncharacterized protein. (494 aa)
	Z520_06730	RNase_PH domain-containing protein. (358 aa)
	Z520_07382	AAA domain-containing protein; Belongs to the AAA ATPase family. (463 aa)
	Z520_00091	NTP_transf_9 domain-containing protein. (163 aa)
	Z520_01717	AAA domain-containing protein; Belongs to the AAA ATPase family. (422 aa)
	Z520_01572	S1 motif domain-containing protein. (351 aa)
	Z520_01526	Uncharacterized protein. (497 aa)
	Z520_07926	RNase_PH domain-containing protein. (278 aa)
	Z520_01315	Uncharacterized protein. (632 aa)
	Z520_00214	Endo/exonuclease/phosphatase domain-containing protein. (746 aa)
	Z520_01625	RBR-type E3 ubiquitin transferase. (519 aa)
	Z520_01263	ATP-dependent RNA helicase dhh1; Belongs to the DEAD box helicase family. (518 aa)
	Z520_05550	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (439 aa)
	Z520_05815	Uncharacterized protein. (585 aa)
	Z520_04073	Tr-type G domain-containing protein. (693 aa)
	Z520_07479	Uncharacterized protein. (1468 aa)
	Z520_05353	RPOL4c domain-containing protein. (152 aa)
	Z520_05668	Uncharacterized protein. (291 aa)
	Z520_09135	KH_dom_type_1 domain-containing protein. (247 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. (200 aa)
	Z520_09605	SAM domain-containing protein. (616 aa)
	Z520_07261	Zn(2)-C6 fungal-type domain-containing protein. (688 aa)
	Z520_07492	RNase_PH domain-containing protein. (362 aa)
	Z520_08030	WD_REPEATS_REGION domain-containing protein. (668 aa)
	Z520_08475	Uncharacterized protein. (1174 aa)
	Z520_11932	BHLH domain-containing protein. (306 aa)
	Z520_09608	Uncharacterized protein. (272 aa)
	Z520_10374	Uncharacterized protein. (447 aa)
	Z520_10593	WD_REPEATS_REGION domain-containing protein. (583 aa)
	Z520_11097	Uncharacterized protein. (86 aa)

Your Current Organism:

Fonsecaea multimorphosa

NCBI taxonomy Id: 1442371
Other names: F. multimorphosa CBS 102226, Fonsecaea multimorphosa CBS 102226

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
INT6	Z520_05550	A0A0D2J1H3	A0A0D2K7D5	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	0.447
INT6	Z520_11283	A0A0D2J1H3	A0A0D2GU33	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Guanine nucleotide-binding protein subunit beta-like protein.	0.976
LSM1	Z520_00091	A0A0D2JVM7	A0A0D2KIX6	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	NTP_transf_9 domain-containing protein.	0.825
LSM1	Z520_00214	A0A0D2JVM7	A0A0D2KBR9	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Endo/exonuclease/phosphatase domain-containing protein.	0.425
LSM1	Z520_00478	A0A0D2JVM7	A0A0D2J2X3	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Nudix hydrolase domain-containing protein.	0.911
LSM1	Z520_00738	A0A0D2JVM7	A0A0D2HQ92	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	PAT1 domain-containing protein.	0.973
LSM1	Z520_01263	A0A0D2JVM7	A0A0D2K9R8	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	ATP-dependent RNA helicase dhh1; Belongs to the DEAD box helicase family.	0.975
LSM1	Z520_01569	A0A0D2JVM7	A0A0D2J143	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	NTP_transf_9 domain-containing protein.	0.825
LSM1	Z520_06281	A0A0D2JVM7	A0A0D2IME4	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.839
PAN2	PAN3	A0A0D2KNT2	A0A0D2IZ68	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]	0.999
PAN2	Z520_00080	A0A0D2KNT2	A0A0D2L2X6	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Uncharacterized protein.	0.505
PAN2	Z520_00214	A0A0D2KNT2	A0A0D2KBR9	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Endo/exonuclease/phosphatase domain-containing protein.	0.737
PAN2	Z520_01263	A0A0D2KNT2	A0A0D2K9R8	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	ATP-dependent RNA helicase dhh1; Belongs to the DEAD box helicase family.	0.455
PAN2	Z520_06041	A0A0D2KNT2	A0A0D2KMR8	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Uncharacterized protein.	0.521
PAN2	Z520_07926	A0A0D2KNT2	A0A0D2KHJ2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	RNase_PH domain-containing protein.	0.436
PAN2	Z520_11049	A0A0D2KNT2	A0A0D2GUH8	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Uncharacterized protein.	0.489
PAN3	PAN2	A0A0D2IZ68	A0A0D2KNT2	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	0.999
PAN3	Z520_00214	A0A0D2IZ68	A0A0D2KBR9	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]	Endo/exonuclease/phosphatase domain-containing protein.	0.599
PAN3	Z520_01263	A0A0D2IZ68	A0A0D2K9R8	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]	ATP-dependent RNA helicase dhh1; Belongs to the DEAD box helicase family.	0.541
PAN3	Z520_06041	A0A0D2IZ68	A0A0D2KMR8	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]	Uncharacterized protein.	0.520