76 items (Fonsecaea multimorphosa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Your Input:
	EFM7	Protein N-terminal and lysine N-methyltransferase EFM7; S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono-and dimethylation of 'Lys-3'. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family. (251 aa)
	Z520_12021	RING-type domain-containing protein. (350 aa)
	Z520_11900	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (173 aa)
	Z520_10743	Uncharacterized protein. (193 aa)
	Z520_10307	N-acetyltransferase domain-containing protein. (300 aa)
	Z520_09741	Uncharacterized protein. (238 aa)
	Z520_07953	Uncharacterized protein. (290 aa)
	Z520_07781	U-box domain-containing protein. (538 aa)
	Z520_07139	Deoxyhypusine synthase. (336 aa)
	Z520_05806	SET domain-containing protein. (830 aa)
	Z520_05501	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (999 aa)
	Z520_04751	WLM domain-containing protein. (323 aa)
	Z520_03896	Uncharacterized protein. (860 aa)
	Z520_03602	Uncharacterized protein. (1630 aa)
	Z520_02913	Ubiquitin-activating enzyme E1-like; Belongs to the ubiquitin-activating E1 family. (625 aa)
	Z520_10572	Actin, gamma. (375 aa)
	Z520_10642	SET domain-containing protein. (638 aa)
	Z520_09862	WD_REPEATS_REGION domain-containing protein. (407 aa)
	Z520_08741	Uncharacterized protein. (617 aa)
	Z520_08129	WD_REPEATS_REGION domain-containing protein. (375 aa)
	Z520_07060	Uncharacterized protein. (245 aa)
	Z520_06823	Chromatin modification-related protein. (788 aa)
	Z520_06684	Uncharacterized protein. (1310 aa)
	Z520_06130	Uncharacterized protein. (545 aa)
	Z520_05597	DUF3591 domain-containing protein. (1112 aa)
	Z520_05042	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3849 aa)
	Z520_04157	Deacetylase sirtuin-type domain-containing protein. (321 aa)
	Z520_02769	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (243 aa)
	Z520_00931	RING-type domain-containing protein. (482 aa)
	Z520_12321	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (293 aa)
	EFM6	Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily. (247 aa)
	Z520_09179	SUMO-conjugating enzyme ubc9; Belongs to the ubiquitin-conjugating enzyme family. (157 aa)
	Z520_11628	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (491 aa)
	Z520_08989	SANT_DAMP1_like domain-containing protein. (851 aa)
	Z520_11068	WD_REPEATS_REGION domain-containing protein. (476 aa)
	Z520_06854	Uncharacterized protein. (396 aa)
	Z520_06410	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1311 aa)
	Z520_09454	Uncharacterized protein. (451 aa)
	Z520_06292	ThiF domain-containing protein. (466 aa)
	Z520_08891	Ubiquitin-like domain-containing protein. (101 aa)
	Z520_08996	BPL/LPL catalytic domain-containing protein. (527 aa)
	Z520_08614	Uncharacterized protein. (551 aa)
	Z520_08411	Uncharacterized protein; Belongs to the glycosyl hydrolase 31 family. (813 aa)
	Z520_07977	Uncharacterized protein. (503 aa)
	Z520_04878	Histone acetyltransferase. (525 aa)
	Z520_07038	Uncharacterized protein. (537 aa)
	Z520_07243	MRG domain-containing protein. (322 aa)
	Z520_04580	Uncharacterized protein. (377 aa)
	Z520_07313	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (457 aa)
	Z520_06736	SGF29 C-terminal domain-containing protein. (317 aa)
	Z520_04063	Uncharacterized protein; Belongs to the actin family. (475 aa)
	Z520_03378	Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (642 aa)
	Z520_06169	ULP_PROTEASE domain-containing protein. (455 aa)
	Z520_05005	Uncharacterized protein. (386 aa)
	Z520_03935	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (420 aa)
	Z520_00459	WD_REPEATS_REGION domain-containing protein. (355 aa)
	Z520_00569	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (550 aa)
	Z520_03716	Uncharacterized protein. (582 aa)
	Z520_09664	Uncharacterized protein. (244 aa)
	Z520_09348	Uncharacterized protein. (399 aa)
	Z520_02188	RING-type domain-containing protein. (300 aa)
	Z520_02463	Uncharacterized protein. (356 aa)
	Z520_01045	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (462 aa)
	Z520_01050	SP-RING-type domain-containing protein. (1013 aa)
	Z520_08298	Bromo domain-containing protein. (1200 aa)
	Z520_08328	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1267 aa)
	Z520_07916	SET domain-containing protein. (485 aa)
	Z520_07879	SET domain-containing protein. (383 aa)
	Z520_00446	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (543 aa)
	Z520_07122	Ribosomal lysine N-methyltransferase 4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that monomethylates 60S ribosomal protein L42. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. (485 aa)
	EFM4	Protein-lysine N-methyltransferase EFM4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family. (343 aa)
	Z520_04814	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (473 aa)
	Z520_04014	Uncharacterized protein. (709 aa)
	Z520_02107	Uncharacterized protein. (270 aa)
	Z520_02282	Uncharacterized protein. (801 aa)
	LIA1	Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. (331 aa)

Your Current Organism:

Fonsecaea multimorphosa

NCBI taxonomy Id: 1442371
Other names: F. multimorphosa CBS 102226, Fonsecaea multimorphosa CBS 102226

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFM4	EFM6	A0A0D2KMY4	A0A0D2JP07	Protein-lysine N-methyltransferase EFM4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.	Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.	0.576
EFM4	EFM7	A0A0D2KMY4	A0A0D2JUZ5	Protein-lysine N-methyltransferase EFM4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.	Protein N-terminal and lysine N-methyltransferase EFM7; S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono-and dimethylation of 'Lys-3'. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.	0.536
EFM4	Z520_02463	A0A0D2KMY4	A0A0D2KFT5	Protein-lysine N-methyltransferase EFM4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.	Uncharacterized protein.	0.599
EFM4	Z520_09741	A0A0D2KMY4	A0A0D2GYR7	Protein-lysine N-methyltransferase EFM4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.	Uncharacterized protein.	0.477
EFM6	EFM4	A0A0D2JP07	A0A0D2KMY4	Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.	Protein-lysine N-methyltransferase EFM4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.	0.576
EFM6	EFM7	A0A0D2JP07	A0A0D2JUZ5	Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.	Protein N-terminal and lysine N-methyltransferase EFM7; S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono-and dimethylation of 'Lys-3'. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.	0.521
EFM6	Z520_04014	A0A0D2JP07	A0A0D2KUA6	Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.	Uncharacterized protein.	0.407
EFM6	Z520_08328	A0A0D2JP07	A0A0D2KHC6	Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	0.434
EFM7	EFM4	A0A0D2JUZ5	A0A0D2KMY4	Protein N-terminal and lysine N-methyltransferase EFM7; S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono-and dimethylation of 'Lys-3'. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.	Protein-lysine N-methyltransferase EFM4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.	0.536
EFM7	EFM6	A0A0D2JUZ5	A0A0D2JP07	Protein N-terminal and lysine N-methyltransferase EFM7; S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono-and dimethylation of 'Lys-3'. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.	Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.	0.521
LIA1	Z520_07139	A0A0D2L418	A0A0D2H5B1	Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.	Deoxyhypusine synthase.	0.931
Z520_00446	Z520_00459	A0A0D2KJV3	A0A0D2KC79	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	WD_REPEATS_REGION domain-containing protein.	0.573
Z520_00446	Z520_01045	A0A0D2KJV3	A0A0D2KGJ8	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.588
Z520_00446	Z520_02188	A0A0D2KJV3	A0A0D2KF67	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	RING-type domain-containing protein.	0.456
Z520_00446	Z520_02282	A0A0D2KJV3	A0A0D2KZB0	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Uncharacterized protein.	0.883
Z520_00446	Z520_03716	A0A0D2KJV3	A0A0D2KCY6	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Uncharacterized protein.	0.502
Z520_00446	Z520_04157	A0A0D2KJV3	A0A0D2IU19	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Deacetylase sirtuin-type domain-containing protein.	0.493
Z520_00446	Z520_05501	A0A0D2KJV3	A0A0D2HAW6	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.923
Z520_00446	Z520_05806	A0A0D2KJV3	A0A0D2H9H4	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	SET domain-containing protein.	0.873
Z520_00446	Z520_07038	A0A0D2KJV3	A0A0D2K1S1	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Uncharacterized protein.	0.860