(15 nodes) Mitotic DNA integrity checkpoint signaling network (Fonsecaea multimorphosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Z520_09987	Checkpoint protein; Belongs to the HUS1 family. (349 aa)
	Z520_01753	HORMA domain-containing protein. (231 aa)
	Z520_00257	Uncharacterized protein. (1059 aa)
	Z520_10860	Uncharacterized protein. (909 aa)
	Z520_02792	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (781 aa)
	Z520_01320	MRC1 domain-containing protein. (1354 aa)
	Z520_00161	ERCC4 domain-containing protein. (636 aa)
	Z520_03203	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (475 aa)
	Z520_00430	Uncharacterized protein. (907 aa)
	Z520_01283	Protein kinase domain-containing protein. (560 aa)
	Z520_11657	Uncharacterized protein. (310 aa)
	Z520_08249	Cell division control protein; Belongs to the CDC6/cdc18 family. (607 aa)
	Z520_09464	Protein kinase domain-containing protein. (540 aa)
	Z520_11350	ERCC4 domain-containing protein. (644 aa)
	Z520_09617	BRCT domain-containing protein. (628 aa)

Your Current Organism:

Fonsecaea multimorphosa

NCBI taxonomy Id: 1442371
Other names: F. multimorphosa CBS 102226, Fonsecaea multimorphosa CBS 102226

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Z520_00161	Z520_00257	A0A0D2KJ26	A0A0D2HP09	ERCC4 domain-containing protein.	Uncharacterized protein.	0.826
Z520_00161	Z520_00430	A0A0D2KJ26	A0A0D2L3V3	ERCC4 domain-containing protein.	Uncharacterized protein.	0.587
Z520_00161	Z520_01283	A0A0D2KJ26	A0A0D2K9U4	ERCC4 domain-containing protein.	Protein kinase domain-containing protein.	0.402
Z520_00161	Z520_02792	A0A0D2KJ26	A0A0D2KDE1	ERCC4 domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.851
Z520_00161	Z520_03203	A0A0D2KJ26	A0A0D2KBS0	ERCC4 domain-containing protein.	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	0.545
Z520_00161	Z520_09464	A0A0D2KJ26	A0A0D2JW82	ERCC4 domain-containing protein.	Protein kinase domain-containing protein.	0.578
Z520_00161	Z520_09617	A0A0D2KJ26	A0A0D2IBP9	ERCC4 domain-containing protein.	BRCT domain-containing protein.	0.584
Z520_00161	Z520_09987	A0A0D2KJ26	A0A0D2JLS0	ERCC4 domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.555
Z520_00161	Z520_10860	A0A0D2KJ26	A0A0D2I8D9	ERCC4 domain-containing protein.	Uncharacterized protein.	0.722
Z520_00161	Z520_11350	A0A0D2KJ26	A0A0D2JQY1	ERCC4 domain-containing protein.	ERCC4 domain-containing protein.	0.952
Z520_00257	Z520_00161	A0A0D2HP09	A0A0D2KJ26	Uncharacterized protein.	ERCC4 domain-containing protein.	0.826
Z520_00257	Z520_00430	A0A0D2HP09	A0A0D2L3V3	Uncharacterized protein.	Uncharacterized protein.	0.608
Z520_00257	Z520_01283	A0A0D2HP09	A0A0D2K9U4	Uncharacterized protein.	Protein kinase domain-containing protein.	0.987
Z520_00257	Z520_01320	A0A0D2HP09	A0A0D2KHC0	Uncharacterized protein.	MRC1 domain-containing protein.	0.989
Z520_00257	Z520_01753	A0A0D2HP09	A0A0D2HN80	Uncharacterized protein.	HORMA domain-containing protein.	0.572
Z520_00257	Z520_02792	A0A0D2HP09	A0A0D2KDE1	Uncharacterized protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.717
Z520_00257	Z520_03203	A0A0D2HP09	A0A0D2KBS0	Uncharacterized protein.	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	0.723
Z520_00257	Z520_08249	A0A0D2HP09	A0A0D2JZI1	Uncharacterized protein.	Cell division control protein; Belongs to the CDC6/cdc18 family.	0.562
Z520_00257	Z520_09464	A0A0D2HP09	A0A0D2JW82	Uncharacterized protein.	Protein kinase domain-containing protein.	0.960
Z520_00257	Z520_09617	A0A0D2HP09	A0A0D2IBP9	Uncharacterized protein.	BRCT domain-containing protein.	0.446