(45 nodes) mRNA cis splicing, via spliceosome network (Fonsecaea multimorphosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Z520_01490	RRM domain-containing protein. (199 aa)
	Z520_11659	Uncharacterized protein. (531 aa)
	Z520_11416	Uncharacterized protein. (385 aa)
	Z520_11333	U1-type domain-containing protein. (299 aa)
	Z520_09101	Uncharacterized protein. (157 aa)
	Z520_08822	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (184 aa)
	Z520_08887	G-patch domain-containing protein. (726 aa)
	Z520_08947	Uncharacterized protein. (693 aa)
	Z520_07736	Nuclear cap-binding protein subunit 2. (173 aa)
	Z520_07811	Uncharacterized protein. (374 aa)
	Z520_05856	WD_REPEATS_REGION domain-containing protein. (334 aa)
	Z520_03497	Uncharacterized protein. (767 aa)
	Z520_02429	Pre-mRNA-processing-splicing factor 8. (2670 aa)
	Z520_10421	Uncharacterized protein. (567 aa)
	Z520_10258	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome. (1418 aa)
	Z520_07777	Tudor domain-containing protein. (293 aa)
	Z520_07847	Uncharacterized protein. (672 aa)
	Z520_07852	Sde2_N_Ubi domain-containing protein. (341 aa)
	Z520_07481	Uncharacterized protein. (446 aa)
	Z520_06341	Uncharacterized protein. (329 aa)
	Z520_02964	Uncharacterized protein. (593 aa)
	Z520_02130	RRM domain-containing protein. (198 aa)
	Z520_02425	Uncharacterized protein. (547 aa)
	Z520_01659	Uncharacterized protein. (678 aa)
	Z520_00123	Protein kinase domain-containing protein. (757 aa)
	Z520_11066	DUF1716 domain-containing protein. (611 aa)
	Z520_09068	Pre-mRNA-splicing factor clf1. (680 aa)
	Z520_07808	DUF2040 domain-containing protein. (412 aa)
	Z520_07416	SNRNP27 domain-containing protein. (277 aa)
	Z520_08179	Uncharacterized protein. (214 aa)
	Z520_07283	Uncharacterized protein. (563 aa)
	Z520_05670	Uncharacterized protein. (205 aa)
	Z520_03055	WD_REPEATS_REGION domain-containing protein. (360 aa)
	Z520_01103	Uncharacterized protein. (207 aa)
	Z520_01183	Uncharacterized protein. (288 aa)
	Z520_00114	CID domain-containing protein. (964 aa)
	Z520_09899	Uncharacterized protein. (518 aa)
	Z520_09629	Matrin-type domain-containing protein. (540 aa)
	Z520_01893	J domain-containing protein. (212 aa)
	Z520_08905	Uncharacterized protein. (262 aa)
	Z520_07548	Uncharacterized protein. (484 aa)
	Z520_06333	Uncharacterized protein. (215 aa)
	Z520_04626	Uncharacterized protein. (218 aa)
	Z520_04034	Uncharacterized protein. (336 aa)
	Z520_02247	Uncharacterized protein. (568 aa)

Your Current Organism:

Fonsecaea multimorphosa

NCBI taxonomy Id: 1442371
Other names: F. multimorphosa CBS 102226, Fonsecaea multimorphosa CBS 102226

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Z520_00114	Z520_00123	A0A0D2KBL9	A0A0D2J249	CID domain-containing protein.	Protein kinase domain-containing protein.	0.708
Z520_00114	Z520_02964	A0A0D2KBL9	A0A0D2IWS9	CID domain-containing protein.	Uncharacterized protein.	0.557
Z520_00114	Z520_03497	A0A0D2KBL9	A0A0D2HG10	CID domain-containing protein.	Uncharacterized protein.	0.608
Z520_00114	Z520_04034	A0A0D2KBL9	A0A0D2KUD1	CID domain-containing protein.	Uncharacterized protein.	0.630
Z520_00114	Z520_07283	A0A0D2KBL9	A0A0D2K293	CID domain-containing protein.	Uncharacterized protein.	0.806
Z520_00114	Z520_07777	A0A0D2KBL9	A0A0D2IHK0	CID domain-containing protein.	Tudor domain-containing protein.	0.989
Z520_00114	Z520_09629	A0A0D2KBL9	A0A0D2KCY4	CID domain-containing protein.	Matrin-type domain-containing protein.	0.834
Z520_00114	Z520_09899	A0A0D2KBL9	A0A0D2KCS1	CID domain-containing protein.	Uncharacterized protein.	0.999
Z520_00114	Z520_11659	A0A0D2KBL9	A0A0D2GT25	CID domain-containing protein.	Uncharacterized protein.	0.762
Z520_00123	Z520_00114	A0A0D2J249	A0A0D2KBL9	Protein kinase domain-containing protein.	CID domain-containing protein.	0.708
Z520_00123	Z520_02247	A0A0D2J249	A0A0D2KZ69	Protein kinase domain-containing protein.	Uncharacterized protein.	0.762
Z520_00123	Z520_02429	A0A0D2J249	A0A0D2HK66	Protein kinase domain-containing protein.	Pre-mRNA-processing-splicing factor 8.	0.920
Z520_00123	Z520_02964	A0A0D2J249	A0A0D2IWS9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.722
Z520_00123	Z520_03055	A0A0D2J249	A0A0D2K6M5	Protein kinase domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.837
Z520_00123	Z520_03497	A0A0D2J249	A0A0D2HG10	Protein kinase domain-containing protein.	Uncharacterized protein.	0.894
Z520_00123	Z520_07416	A0A0D2J249	A0A0D2JT89	Protein kinase domain-containing protein.	SNRNP27 domain-containing protein.	0.485
Z520_00123	Z520_07847	A0A0D2J249	A0A0D2IHR3	Protein kinase domain-containing protein.	Uncharacterized protein.	0.889
Z520_00123	Z520_08822	A0A0D2J249	A0A0D2H0G5	Protein kinase domain-containing protein.	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.	0.722
Z520_00123	Z520_09629	A0A0D2J249	A0A0D2KCY4	Protein kinase domain-containing protein.	Matrin-type domain-containing protein.	0.660
Z520_00123	Z520_10421	A0A0D2J249	A0A0D2I9E3	Protein kinase domain-containing protein.	Uncharacterized protein.	0.402