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Z520_10883 Z520_10883 Z520_03935 Z520_03935 Z520_04015 Z520_04015 Z520_09754 Z520_09754 Z520_09124 Z520_09124 Z520_07884 Z520_07884 Z520_04231 Z520_04231 Z520_03359 Z520_03359 Z520_04667 Z520_04667 Z520_00370 Z520_00370 Z520_09071 Z520_09071 Z520_06503 Z520_06503 Z520_06583 Z520_06583 Z520_05941 Z520_05941 Z520_04486 Z520_04486 DRE2 DRE2 Z520_01944 Z520_01944 Z520_01126 Z520_01126 Z520_01401 Z520_01401 CFD1 CFD1 Z520_11429 Z520_11429 NTH1 NTH1 Z520_09536 Z520_09536 Z520_06973 Z520_06973 Z520_05652 Z520_05652 Z520_05182 Z520_05182 Z520_03200 Z520_03200 Z520_02904 Z520_02904 NBP35 NBP35 Z520_01387 Z520_01387 Z520_10882 Z520_10882 Z520_09698 Z520_09698 Z520_08682 Z520_08682 Z520_11166 Z520_11166 Z520_10286 Z520_10286 Z520_10336 Z520_10336 Z520_10135 Z520_10135 Z520_09875 Z520_09875 Z520_09890 Z520_09890 Z520_06914 Z520_06914 Z520_06665 Z520_06665 Z520_06076 Z520_06076 Z520_08846 Z520_08846 Z520_03818 Z520_03818 Z520_06881 Z520_06881 Z520_03604 Z520_03604 Z520_05680 Z520_05680 Z520_01800 Z520_01800 Z520_11852 Z520_11852 Z520_11714 Z520_11714 Z520_04556 Z520_04556 Z520_04688 Z520_04688
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Z520_10883Uncharacterized protein. (677 aa)
Z520_03935Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (420 aa)
Z520_04015NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (506 aa)
Z520_09754Uncharacterized protein. (1703 aa)
Z520_09124Fe_hyd_lg_C domain-containing protein; Belongs to the NARF family. (605 aa)
Z520_07884Uncharacterized protein. (289 aa)
Z520_04231DNA repair helicase rad15. (815 aa)
Z520_033593-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (775 aa)
Z520_04667Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (782 aa)
Z520_00370Uncharacterized protein. (651 aa)
Z520_09071Translation initiation factor RLI1. (604 aa)
Z520_065032-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily. (580 aa)
Z520_06583Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (297 aa)
Z520_05941Sacchrp_dh_NADP domain-containing protein. (452 aa)
Z520_04486Uncharacterized protein. (760 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (330 aa)
Z520_01944Flavodoxin-like domain-containing protein. (1552 aa)
Z520_01126NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial. (231 aa)
Z520_01401Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (748 aa)
CFD1Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (321 aa)
Z520_11429Uncharacterized protein. (762 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (430 aa)
Z520_09536Elp3 domain-containing protein. (951 aa)
Z520_06973Rieske domain-containing protein. (1117 aa)
Z520_05652Uncharacterized protein. (407 aa)
Z520_05182NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. (494 aa)
Z520_03200Fe-S_biosyn domain-containing protein. (227 aa)
Z520_02904Flavodoxin-like domain-containing protein. (797 aa)
NBP35Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (342 aa)
Z520_01387Uncharacterized protein. (840 aa)
Z520_10882Uncharacterized protein. (216 aa)
Z520_09698DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2240 aa)
Z520_08682MaoC-like domain-containing protein. (375 aa)
Z520_11166Nfu_N domain-containing protein. (314 aa)
Z520_10286Uncharacterized protein. (697 aa)
Z520_10336Uncharacterized protein. (1056 aa)
Z520_10135NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. (741 aa)
Z520_09875Uncharacterized protein. (435 aa)
Z520_09890Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (808 aa)
Z520_069142-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (446 aa)
Z520_06665Uncharacterized protein. (411 aa)
Z520_06076Aconitase_C domain-containing protein. (157 aa)
Z520_08846NADH-ubiquinone oxidoreductase 19.3 kDa subunit, mitochondrial; Belongs to the complex I 20 kDa subunit family. (232 aa)
Z520_03818Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (575 aa)
Z520_06881DNA polymerase. (1699 aa)
Z520_03604DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (503 aa)
Z520_05680Uncharacterized protein. (322 aa)
Z520_01800Uncharacterized protein. (871 aa)
Z520_11852DNA polymerase. (1107 aa)
Z520_11714Uncharacterized protein. (839 aa)
Z520_04556Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (635 aa)
Z520_04688Uncharacterized protein. (848 aa)
Your Current Organism:
Fonsecaea multimorphosa
NCBI taxonomy Id: 1442371
Other names: F. multimorphosa CBS 102226, Fonsecaea multimorphosa CBS 102226
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