node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Z520_01081 | Z520_01566 | A0A0D2HL22 | A0A0D2L201 | Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.505 |
Z520_01081 | Z520_06399 | A0A0D2HL22 | A0A0D2IKS9 | Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] | 0.986 |
Z520_01566 | Z520_01081 | A0A0D2L201 | A0A0D2HL22 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. | 0.505 |
Z520_01566 | Z520_01717 | A0A0D2L201 | A0A0D2KIE3 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.464 |
Z520_01566 | Z520_01872 | A0A0D2L201 | A0A0D2KY21 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. | 0.578 |
Z520_01566 | Z520_03562 | A0A0D2L201 | A0A0D2HGA6 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. | 0.502 |
Z520_01566 | Z520_04542 | A0A0D2L201 | A0A0D2HDF1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. | 0.502 |
Z520_01566 | Z520_06399 | A0A0D2L201 | A0A0D2IKS9 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] | 0.610 |
Z520_01566 | Z520_10416 | A0A0D2L201 | A0A0D2I9D8 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. | 0.460 |
Z520_01717 | Z520_01566 | A0A0D2KIE3 | A0A0D2L201 | AAA domain-containing protein; Belongs to the AAA ATPase family. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.464 |
Z520_01717 | Z520_03562 | A0A0D2KIE3 | A0A0D2HGA6 | AAA domain-containing protein; Belongs to the AAA ATPase family. | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. | 0.999 |
Z520_01717 | Z520_04542 | A0A0D2KIE3 | A0A0D2HDF1 | AAA domain-containing protein; Belongs to the AAA ATPase family. | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. | 0.999 |
Z520_01717 | Z520_10416 | A0A0D2KIE3 | A0A0D2I9D8 | AAA domain-containing protein; Belongs to the AAA ATPase family. | 26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. | 0.999 |
Z520_01872 | Z520_01566 | A0A0D2KY21 | A0A0D2L201 | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.578 |
Z520_03418 | Z520_04676 | A0A0D2K4L3 | A0A0D2K2G3 | CBFD_NFYB_HMF domain-containing protein. | Uncharacterized protein. | 0.923 |
Z520_03562 | Z520_01566 | A0A0D2HGA6 | A0A0D2L201 | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.502 |
Z520_03562 | Z520_01717 | A0A0D2HGA6 | A0A0D2KIE3 | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.999 |
Z520_03562 | Z520_04542 | A0A0D2HGA6 | A0A0D2HDF1 | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. | 0.999 |
Z520_03562 | Z520_10416 | A0A0D2HGA6 | A0A0D2I9D8 | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. | 26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. | 0.999 |
Z520_04542 | Z520_01566 | A0A0D2HDF1 | A0A0D2L201 | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.502 |