24 items (Fonsecaea multimorphosa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Your Input:
	Z520_06399	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (582 aa)
	Z520_09405	RNA-dependent RNA polymerase. (1175 aa)
	Z520_09305	Uncharacterized protein. (1287 aa)
	Z520_08402	Chromo domain-containing protein. (271 aa)
	Z520_06742	Uncharacterized protein. (784 aa)
	Z520_06802	DNA helicase; Belongs to the MCM family. (894 aa)
	Z520_00547	CULLIN_2 domain-containing protein; Belongs to the cullin family. (829 aa)
	Z520_11776	Histone H2A; Belongs to the histone H2A family. (139 aa)
	Z520_08499	RNA-dependent RNA polymerase. (1407 aa)
	Z520_07060	Uncharacterized protein. (245 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (814 aa)
	Z520_03942	Deacetylase sirtuin-type domain-containing protein. (649 aa)
	Z520_02629	C2H2-type domain-containing protein. (1436 aa)
	Z520_12380	DNA helicase; Belongs to the MCM family. (725 aa)
	Z520_11628	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (491 aa)
	Z520_06741	Stc1 domain-containing protein. (260 aa)
	Z520_01901	Uncharacterized protein. (887 aa)
	Z520_11083	Hist_deacetyl domain-containing protein. (364 aa)
	Z520_08743	Deacetylase sirtuin-type domain-containing protein. (608 aa)
	Z520_01045	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (462 aa)
	Z520_00446	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (543 aa)
	Z520_07578	Uncharacterized protein. (1681 aa)
	Z520_05329	Uncharacterized protein. (2323 aa)
	Z520_00545	Uncharacterized protein. (1166 aa)

Your Current Organism:

Fonsecaea multimorphosa

NCBI taxonomy Id: 1442371
Other names: F. multimorphosa CBS 102226, Fonsecaea multimorphosa CBS 102226

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	Z520_06399	A0A0D2ILH4	A0A0D2IKS9	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	0.676
MCM7	Z520_06802	A0A0D2ILH4	A0A0D2H684	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	Z520_11776	A0A0D2ILH4	A0A0D2I5D5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Histone H2A; Belongs to the histone H2A family.	0.564
MCM7	Z520_12380	A0A0D2ILH4	A0A0D2JFH9	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
Z520_00446	Z520_01045	A0A0D2KJV3	A0A0D2KGJ8	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.588
Z520_00446	Z520_03942	A0A0D2KJV3	A0A0D2ITF8	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Deacetylase sirtuin-type domain-containing protein.	0.493
Z520_00446	Z520_07060	A0A0D2KJV3	A0A0D2IIX1	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Uncharacterized protein.	0.456
Z520_00446	Z520_08743	A0A0D2KJV3	A0A0D2KG23	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Deacetylase sirtuin-type domain-containing protein.	0.493
Z520_00446	Z520_11776	A0A0D2KJV3	A0A0D2I5D5	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	Histone H2A; Belongs to the histone H2A family.	0.413
Z520_00547	Z520_07578	A0A0D2HPT1	A0A0D2KJW5	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Uncharacterized protein.	0.523
Z520_00547	Z520_08402	A0A0D2HPT1	A0A0D2H1I1	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Chromo domain-containing protein.	0.507
Z520_01045	Z520_00446	A0A0D2KGJ8	A0A0D2KJV3	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.588
Z520_01045	Z520_01901	A0A0D2KGJ8	A0A0D2K748	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.638
Z520_01045	Z520_03942	A0A0D2KGJ8	A0A0D2ITF8	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Deacetylase sirtuin-type domain-containing protein.	0.421
Z520_01045	Z520_07060	A0A0D2KGJ8	A0A0D2IIX1	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.871
Z520_01045	Z520_07578	A0A0D2KGJ8	A0A0D2KJW5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.440
Z520_01045	Z520_08743	A0A0D2KGJ8	A0A0D2KG23	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Deacetylase sirtuin-type domain-containing protein.	0.421
Z520_01045	Z520_11083	A0A0D2KGJ8	A0A0D2KA04	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Hist_deacetyl domain-containing protein.	0.638
Z520_01045	Z520_11776	A0A0D2KGJ8	A0A0D2I5D5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Histone H2A; Belongs to the histone H2A family.	0.759
Z520_01901	Z520_01045	A0A0D2K748	A0A0D2KGJ8	Uncharacterized protein.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.638