40 items (Fonsecaea multimorphosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Z520_01818	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (470 aa)
	Z520_10933	AlcB domain-containing protein. (445 aa)
	Z520_09716	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450. (720 aa)
	Z520_06693	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (485 aa)
	Z520_05201	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (366 aa)
	Z520_05276	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (281 aa)
	Z520_04966	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (285 aa)
	Z520_04218	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (250 aa)
	cprA	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (691 aa)
	Z520_10092	Uncharacterized protein. (568 aa)
	Z520_08484	Uncharacterized protein; Belongs to the cytochrome P450 family. (533 aa)
	Z520_07085	Uncharacterized protein. (219 aa)
	Z520_06838	Uncharacterized protein. (449 aa)
	Z520_04917	Uncharacterized protein. (365 aa)
	Z520_03947	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (286 aa)
	Z520_02315	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (399 aa)
	Z520_01137	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (384 aa)
	Z520_01307	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (346 aa)
	Z520_00473	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (469 aa)
	Z520_10935	Uncharacterized protein. (2111 aa)
	Z520_10685	Uncharacterized protein. (152 aa)
	Z520_10462	Uncharacterized protein. (488 aa)
	Z520_10932	Uncharacterized protein. (278 aa)
	Z520_07196	Uncharacterized protein. (325 aa)
	Z520_06081	Uncharacterized protein. (495 aa)
	Z520_06101	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (356 aa)
	Z520_06287	Uncharacterized protein. (598 aa)
	Z520_08364	3Beta_HSD domain-containing protein. (403 aa)
	Z520_04768	Uncharacterized protein. (257 aa)
	Z520_04988	Uncharacterized protein. (594 aa)
	Z520_07393	FAD-binding FR-type domain-containing protein. (392 aa)
	Z520_06452	Uncharacterized protein. (607 aa)
	Z520_06314	Uncharacterized protein. (290 aa)
	Z520_11135	3Beta_HSD domain-containing protein. (461 aa)
	Z520_10931	Uncharacterized protein. (591 aa)
	Z520_00264	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (409 aa)
	Z520_03566	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (313 aa)
	Z520_02619	EXPERA domain-containing protein. (264 aa)
	Z520_03839	Uncharacterized protein. (491 aa)
	Z520_01500	FAD-binding PCMH-type domain-containing protein. (552 aa)

Your Current Organism:

Fonsecaea multimorphosa

NCBI taxonomy Id: 1442371
Other names: F. multimorphosa CBS 102226, Fonsecaea multimorphosa CBS 102226

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Z520_00264	Z520_00473	A0A0D2KBV0	A0A0D2J2W7	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.981
Z520_00264	Z520_01818	A0A0D2KBV0	A0A0D2HID3	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.540
Z520_00264	Z520_03566	A0A0D2KBV0	A0A0D2KCL8	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.521
Z520_00264	Z520_03839	A0A0D2KBV0	A0A0D2KTR1	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.549
Z520_00264	Z520_03947	A0A0D2KBV0	A0A0D2ITG4	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.731
Z520_00264	Z520_04218	A0A0D2KBV0	A0A0D2HCF7	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.731
Z520_00264	Z520_04966	A0A0D2KBV0	A0A0D2HBY0	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.731
Z520_00264	Z520_05276	A0A0D2KBV0	A0A0D2HAB5	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.731
Z520_00264	Z520_06081	A0A0D2KBV0	A0A0D2JWR2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.627
Z520_00264	Z520_06314	A0A0D2KBV0	A0A0D2K4Y7	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.731
Z520_00264	Z520_06693	A0A0D2KBV0	A0A0D2H7Y1	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.798
Z520_00264	Z520_06838	A0A0D2KBV0	A0A0D2IK05	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.560
Z520_00264	Z520_08484	A0A0D2KBV0	A0A0D2IF90	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.523
Z520_00264	Z520_10092	A0A0D2KBV0	A0A0D2IA88	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.545
Z520_00264	Z520_10462	A0A0D2KBV0	A0A0D2JKQ1	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.618
Z520_00264	Z520_10932	A0A0D2KBV0	A0A0D2JS77	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.731
Z520_00264	Z520_11135	A0A0D2KBV0	A0A0D2K9K4	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	3Beta_HSD domain-containing protein.	0.541
Z520_00473	Z520_00264	A0A0D2J2W7	A0A0D2KBV0	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.981
Z520_00473	Z520_01137	A0A0D2J2W7	A0A0D2IZY5	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	0.574
Z520_00473	Z520_01500	A0A0D2J2W7	A0A0D2L1V2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	FAD-binding PCMH-type domain-containing protein.	0.614