STRINGSTRING
Z520_11963 Z520_11963 Z520_11572 Z520_11572 Z520_11147 Z520_11147 Z520_10146 Z520_10146 Z520_09606 Z520_09606 Z520_08897 Z520_08897 Z520_07871 Z520_07871 Z520_07254 Z520_07254 Z520_04866 Z520_04866 Z520_03522 Z520_03522 Z520_03732 Z520_03732 Z520_02069 Z520_02069 Z520_01441 Z520_01441 Z520_01618 Z520_01618 Z520_12292 Z520_12292 Z520_11055 Z520_11055 Z520_09812 Z520_09812 Z520_09546 Z520_09546 Z520_09112 Z520_09112 Z520_08746 Z520_08746 Z520_08776 Z520_08776 Z520_08459 Z520_08459 Z520_08019 Z520_08019 Z520_06125 Z520_06125 Z520_06221 Z520_06221 Z520_04112 Z520_04112 Z520_03357 Z520_03357 Z520_02270 Z520_02270 Z520_02365 Z520_02365 Z520_01347 Z520_01347 Z520_10437 Z520_10437 Z520_09758 Z520_09758 Z520_07863 Z520_07863 Z520_06106 Z520_06106 Z520_09329 Z520_09329 Z520_03763 Z520_03763 Z520_06996 Z520_06996 Z520_03963 Z520_03963 Z520_05755 Z520_05755 Z520_03030 Z520_03030 Z520_05410 Z520_05410 Z520_04237 Z520_04237 Z520_11339 Z520_11339 Z520_01218 Z520_01218 Z520_01348 Z520_01348 Z520_01433 Z520_01433 Z520_10706 Z520_10706 Z520_10270 Z520_10270 Z520_03238 Z520_03238 Z520_00519 Z520_00519 Z520_09323 Z520_09323 Z520_01843 Z520_01843 Z520_01918 Z520_01918 Z520_02008 Z520_02008 Z520_08825 Z520_08825 Z520_01300 Z520_01300 Z520_01642 Z520_01642 Z520_07679 Z520_07679 Z520_00041 Z520_00041 Z520_07417 Z520_07417 Z520_00491 Z520_00491 Z520_07623 Z520_07623 Z520_04909 Z520_04909 Z520_00676 Z520_00676
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Z520_11963Uncharacterized protein. (610 aa)
Z520_11572Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (244 aa)
Z520_11147Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (922 aa)
Z520_10146MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (449 aa)
Z520_09606Mitochondrial import inner membrane translocase subunit tim9. (90 aa)
Z520_08897Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (1031 aa)
Z520_07871AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (193 aa)
Z520_07254Protein transport protein BOS1; SNARE required for protein transport between the ER and the Golgi complex. (261 aa)
Z520_04866Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (871 aa)
Z520_03522Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (255 aa)
Z520_03732Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (775 aa)
Z520_02069Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (600 aa)
Z520_01441AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (708 aa)
Z520_01618Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (998 aa)
Z520_12292Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3183 aa)
Z520_11055Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (1038 aa)
Z520_09812VPS37 C-terminal domain-containing protein. (304 aa)
Z520_09546GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (217 aa)
Z520_09112Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (958 aa)
Z520_08746Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. (225 aa)
Z520_08776Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (521 aa)
Z520_08459zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (155 aa)
Z520_08019Exocyst complex protein EXO70; Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst. Belongs to the EXO70 family. (631 aa)
Z520_06125MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (444 aa)
Z520_06221WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (901 aa)
Z520_04112Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (167 aa)
Z520_03357Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (858 aa)
Z520_02270Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (111 aa)
Z520_02365Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (523 aa)
Z520_01347Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (767 aa)
Z520_10437AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1034 aa)
Z520_09758Protein transport protein SFT2; Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex. Belongs to the SFT2 family. (215 aa)
Z520_07863GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (1028 aa)
Z520_06106Protein transport protein sec16; Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy; Belongs to the SEC16 family. (1890 aa)
Z520_09329Uncharacterized protein. (993 aa)
Z520_03763AP-1 complex subunit gamma. (824 aa)
Z520_06996AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
Z520_03963Exocyst complex component SEC5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (1034 aa)
Z520_05755Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (745 aa)
Z520_03030Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (298 aa)
Z520_05410Sortilin; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. (1512 aa)
Z520_04237AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (165 aa)
Z520_11339E3 ubiquitin-protein ligase PEP5. (980 aa)
Z520_01218Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (534 aa)
Z520_01348Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1209 aa)
Z520_01433Protein transporter SEC24. (948 aa)
Z520_10706WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (490 aa)
Z520_10270AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (915 aa)
Z520_03238AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (709 aa)
Z520_00519Importin subunit alpha; Belongs to the importin alpha family. (552 aa)
Z520_09323Vacuolar protein sorting-associated protein 17; Plays a role in vesicular protein sorting. Belongs to the VPS17 family. (620 aa)
Z520_0184360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (516 aa)
Z520_01918GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (229 aa)
Z520_02008Protein BCP1; Involved in nuclear export, actin cytoskeleton organization and vesicular transport; Belongs to the BCP1 family. (290 aa)
Z520_08825MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (554 aa)
Z520_01300Mitochondrial import inner membrane translocase subunit tim10. (99 aa)
Z520_01642Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events. (754 aa)
Z520_07679Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (202 aa)
Z520_00041Small COPII coat GTPase sar1; Belongs to the small GTPase superfamily. SAR1 family. (189 aa)
Z520_07417Autophagy-related protein 3. (366 aa)
Z520_00491Adaptin_N domain-containing protein. (798 aa)
Z520_07623zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (95 aa)
Z520_04909ER lumen protein-retaining receptor. (202 aa)
Z520_00676Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (830 aa)
Your Current Organism:
Fonsecaea multimorphosa
NCBI taxonomy Id: 1442371
Other names: F. multimorphosa CBS 102226, Fonsecaea multimorphosa CBS 102226
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