(67 nodes) Disease network (Fonsecaea multimorphosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Z520_07278	Uncharacterized protein. (219 aa)
	Z520_11644	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (601 aa)
	Z520_10804	Importin N-terminal domain-containing protein. (1085 aa)
	Z520_10864	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (512 aa)
	Z520_09581	Uncharacterized protein. (763 aa)
	Z520_08180	Protein kinase domain-containing protein. (576 aa)
	Z520_07480	Uncharacterized protein. (796 aa)
	Z520_06573	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (744 aa)
	Z520_02848	Uncharacterized protein. (613 aa)
	Z520_01859	Uncharacterized protein. (695 aa)
	Z520_01869	Uncharacterized protein. (292 aa)
	Z520_00788	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (440 aa)
	Z520_11153	Glyco_hydro_63 domain-containing protein. (1051 aa)
	Z520_10283	TPR_REGION domain-containing protein. (571 aa)
	Z520_06499	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (294 aa)
	Z520_06211	Uncharacterized protein. (880 aa)
	Z520_05232	Uncharacterized protein. (751 aa)
	Z520_04311	Lactamase_B domain-containing protein. (440 aa)
	Z520_03997	Uncharacterized protein. (448 aa)
	Z520_04172	NmrA domain-containing protein. (302 aa)
	Z520_03653	NmrA domain-containing protein. (323 aa)
	Z520_03119	Coronin; Belongs to the WD repeat coronin family. (600 aa)
	Z520_01925	NmrA domain-containing protein. (314 aa)
	Z520_02586	CNH domain-containing protein. (1203 aa)
	Z520_00423	Lactamase_B domain-containing protein. (351 aa)
	Z520_09272	LMWPc domain-containing protein. (167 aa)
	Z520_08844	Thioredoxin domain-containing protein. (339 aa)
	Z520_08105	Lactamase_B domain-containing protein. (414 aa)
	Z520_10645	Uncharacterized protein. (374 aa)
	Z520_07101	Oligosaccharide translocation protein RFT1; May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane; Belongs to the RFT1 family. (598 aa)
	Z520_10301	NAD(P)-bd_dom domain-containing protein. (310 aa)
	Z520_07342	CNH domain-containing protein. (996 aa)
	Z520_09399	Uncharacterized protein. (608 aa)
	Z520_09359	Uncharacterized protein. (245 aa)
	Z520_08921	HTH La-type RNA-binding domain-containing protein. (1186 aa)
	Z520_05178	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (661 aa)
	Z520_08299	Importin N-terminal domain-containing protein. (1101 aa)
	Z520_07775	GST N-terminal domain-containing protein. (245 aa)
	Z520_04575	HET domain-containing protein. (702 aa)
	Z520_06716	Uncharacterized protein. (308 aa)
	Z520_04103	Uncharacterized protein. (258 aa)
	Z520_06254	Pep3_Vps18 domain-containing protein. (966 aa)
	Z520_03704	Uncharacterized protein. (206 aa)
	Z520_02680	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (189 aa)
	Z520_12398	Protein kinase domain-containing protein. (396 aa)
	Z520_12332	NmrA domain-containing protein. (307 aa)
	Z520_12207	HET domain-containing protein. (777 aa)
	Z520_02176	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. (860 aa)
	Z520_02211	GST N-terminal domain-containing protein. (279 aa)
	Z520_04940	Uncharacterized protein; Belongs to the glycosyl hydrolase 31 family. (960 aa)
	Z520_11339	E3 ubiquitin-protein ligase PEP5. (980 aa)
	Z520_01318	Uncharacterized protein. (471 aa)
	Z520_10847	PH domain-containing protein. (1467 aa)
	Z520_03410	NmrA domain-containing protein. (344 aa)
	Z520_03516	Protein kinase domain-containing protein. (611 aa)
	Z520_02967	Uncharacterized protein. (391 aa)
	Z520_09180	Uncharacterized protein. (536 aa)
	Z520_08178	Zn(2)-C6 fungal-type domain-containing protein. (649 aa)
	Z520_06168	Uncharacterized protein. (394 aa)
	Z520_05739	Uncharacterized protein. (430 aa)
	Z520_04694	NmrA domain-containing protein. (307 aa)
	Z520_05019	Uncharacterized protein. (334 aa)
	Z520_04444	Lactamase_B domain-containing protein. (383 aa)
	Z520_04189	Uncharacterized protein; Belongs to the glycosyl hydrolase 31 family. (689 aa)
	Z520_03262	Uncharacterized protein. (693 aa)
	Z520_00984	Uncharacterized protein. (560 aa)
	Z520_00676	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (830 aa)

Your Current Organism:

Fonsecaea multimorphosa

NCBI taxonomy Id: 1442371
Other names: F. multimorphosa CBS 102226, Fonsecaea multimorphosa CBS 102226

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Z520_00676	Z520_02586	A0A0D2L4K5	A0A0D2IZH4	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	CNH domain-containing protein.	0.996
Z520_00676	Z520_05178	A0A0D2L4K5	A0A0D2JYV7	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.997
Z520_00676	Z520_06254	A0A0D2L4K5	A0A0D2K4S9	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Pep3_Vps18 domain-containing protein.	0.997
Z520_00676	Z520_07342	A0A0D2L4K5	A0A0D2JUS6	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	CNH domain-containing protein.	0.998
Z520_00676	Z520_11339	A0A0D2L4K5	A0A0D2K934	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	E3 ubiquitin-protein ligase PEP5.	0.997
Z520_00984	Z520_01318	A0A0D2L0I0	A0A0D2K9Y9	Uncharacterized protein.	Uncharacterized protein.	0.551
Z520_00984	Z520_03262	A0A0D2L0I0	A0A0D2KV25	Uncharacterized protein.	Uncharacterized protein.	0.843
Z520_01318	Z520_00984	A0A0D2K9Y9	A0A0D2L0I0	Uncharacterized protein.	Uncharacterized protein.	0.551
Z520_01318	Z520_03262	A0A0D2K9Y9	A0A0D2KV25	Uncharacterized protein.	Uncharacterized protein.	0.551
Z520_01869	Z520_06573	A0A0D2HII6	A0A0D2H7H8	Uncharacterized protein.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.518
Z520_01869	Z520_07480	A0A0D2HII6	A0A0D2H4I6	Uncharacterized protein.	Uncharacterized protein.	0.603
Z520_01869	Z520_11153	A0A0D2HII6	A0A0D2I792	Uncharacterized protein.	Glyco_hydro_63 domain-containing protein.	0.603
Z520_01869	Z520_11644	A0A0D2HII6	A0A0D2GT10	Uncharacterized protein.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.518
Z520_02176	Z520_06211	A0A0D2K7N0	A0A0D2IM81	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	Uncharacterized protein.	0.603
Z520_02176	Z520_06573	A0A0D2K7N0	A0A0D2H7H8	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.706
Z520_02176	Z520_07480	A0A0D2K7N0	A0A0D2H4I6	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	Uncharacterized protein.	0.791
Z520_02176	Z520_11153	A0A0D2K7N0	A0A0D2I792	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	Glyco_hydro_63 domain-containing protein.	0.603
Z520_02176	Z520_11644	A0A0D2K7N0	A0A0D2GT10	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.688
Z520_02586	Z520_00676	A0A0D2IZH4	A0A0D2L4K5	CNH domain-containing protein.	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	0.996
Z520_02586	Z520_05178	A0A0D2IZH4	A0A0D2JYV7	CNH domain-containing protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.994