(8 nodes) Azathioprine ADME network (Fonsecaea multimorphosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Z520_09508	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (219 aa)
	Z520_04941	Nucleoside diphosphate kinase. (154 aa)
	Z520_02009	GMP synthase [glutamine-hydrolyzing]. (548 aa)
	Z520_02370	Uncharacterized protein. (686 aa)
	Z520_11028	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (549 aa)
	Z520_09860	Guanylate kinase-like domain-containing protein. (213 aa)
	Z520_02727	Uncharacterized protein. (277 aa)
	Z520_03081	Uncharacterized protein. (481 aa)

Your Current Organism:

Fonsecaea multimorphosa

NCBI taxonomy Id: 1442371
Other names: F. multimorphosa CBS 102226, Fonsecaea multimorphosa CBS 102226

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Z520_02009	Z520_02727	A0A0D2HJ02	A0A0D2KD89	GMP synthase [glutamine-hydrolyzing].	Uncharacterized protein.	0.842
Z520_02009	Z520_04941	A0A0D2HJ02	A0A0D2HBU9	GMP synthase [glutamine-hydrolyzing].	Nucleoside diphosphate kinase.	0.595
Z520_02009	Z520_09508	A0A0D2HJ02	A0A0D2KDN7	GMP synthase [glutamine-hydrolyzing].	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	0.524
Z520_02009	Z520_09860	A0A0D2HJ02	A0A0D2JVD2	GMP synthase [glutamine-hydrolyzing].	Guanylate kinase-like domain-containing protein.	0.864
Z520_02009	Z520_11028	A0A0D2HJ02	A0A0D2JRV0	GMP synthase [glutamine-hydrolyzing].	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.996
Z520_02370	Z520_03081	A0A0D2IYV4	A0A0D2KXH7	Uncharacterized protein.	Uncharacterized protein.	0.464
Z520_02727	Z520_02009	A0A0D2KD89	A0A0D2HJ02	Uncharacterized protein.	GMP synthase [glutamine-hydrolyzing].	0.842
Z520_02727	Z520_04941	A0A0D2KD89	A0A0D2HBU9	Uncharacterized protein.	Nucleoside diphosphate kinase.	0.860
Z520_02727	Z520_11028	A0A0D2KD89	A0A0D2JRV0	Uncharacterized protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.827
Z520_03081	Z520_02370	A0A0D2KXH7	A0A0D2IYV4	Uncharacterized protein.	Uncharacterized protein.	0.464
Z520_03081	Z520_11028	A0A0D2KXH7	A0A0D2JRV0	Uncharacterized protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.450
Z520_04941	Z520_02009	A0A0D2HBU9	A0A0D2HJ02	Nucleoside diphosphate kinase.	GMP synthase [glutamine-hydrolyzing].	0.595
Z520_04941	Z520_02727	A0A0D2HBU9	A0A0D2KD89	Nucleoside diphosphate kinase.	Uncharacterized protein.	0.860
Z520_04941	Z520_09508	A0A0D2HBU9	A0A0D2KDN7	Nucleoside diphosphate kinase.	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	0.810
Z520_04941	Z520_09860	A0A0D2HBU9	A0A0D2JVD2	Nucleoside diphosphate kinase.	Guanylate kinase-like domain-containing protein.	0.866
Z520_04941	Z520_11028	A0A0D2HBU9	A0A0D2JRV0	Nucleoside diphosphate kinase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.617
Z520_09508	Z520_02009	A0A0D2KDN7	A0A0D2HJ02	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	GMP synthase [glutamine-hydrolyzing].	0.524
Z520_09508	Z520_04941	A0A0D2KDN7	A0A0D2HBU9	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	Nucleoside diphosphate kinase.	0.810
Z520_09508	Z520_11028	A0A0D2KDN7	A0A0D2JRV0	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.537
Z520_09860	Z520_02009	A0A0D2JVD2	A0A0D2HJ02	Guanylate kinase-like domain-containing protein.	GMP synthase [glutamine-hydrolyzing].	0.864