(12 nodes) Aconitase family (aconitate hydratase) network (Fonsecaea multimorphosa)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	Z520_03359	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (775 aa)
	Z520_10883	Uncharacterized protein. (677 aa)
	Z520_04688	Uncharacterized protein. (848 aa)
	Z520_11714	Uncharacterized protein. (839 aa)
	Z520_01800	Uncharacterized protein. (871 aa)
	Z520_09890	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (808 aa)
	Z520_10286	Uncharacterized protein. (697 aa)
	Z520_01387	Uncharacterized protein. (840 aa)
	Z520_11429	Uncharacterized protein. (762 aa)
	Z520_01401	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (748 aa)
	Z520_04486	Uncharacterized protein. (760 aa)
	Z520_04667	Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (782 aa)

Your Current Organism:

Fonsecaea multimorphosa

NCBI taxonomy Id: 1442371
Other names: F. multimorphosa CBS 102226, Fonsecaea multimorphosa CBS 102226

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Z520_01387	Z520_03359	A0A0D2J0R3	A0A0D2KVA9	Uncharacterized protein.	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.471
Z520_01387	Z520_04486	A0A0D2J0R3	A0A0D2HD89	Uncharacterized protein.	Uncharacterized protein.	0.471
Z520_01387	Z520_11429	A0A0D2J0R3	A0A0D2I6A9	Uncharacterized protein.	Uncharacterized protein.	0.471
Z520_01401	Z520_03359	A0A0D2HM54	A0A0D2KVA9	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.556
Z520_01401	Z520_04486	A0A0D2HM54	A0A0D2HD89	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	Uncharacterized protein.	0.556
Z520_01401	Z520_09890	A0A0D2HM54	A0A0D2JVG6	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.924
Z520_01401	Z520_11429	A0A0D2HM54	A0A0D2I6A9	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	Uncharacterized protein.	0.556
Z520_01800	Z520_03359	A0A0D2K6W6	A0A0D2KVA9	Uncharacterized protein.	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.471
Z520_01800	Z520_04486	A0A0D2K6W6	A0A0D2HD89	Uncharacterized protein.	Uncharacterized protein.	0.471
Z520_01800	Z520_11429	A0A0D2K6W6	A0A0D2I6A9	Uncharacterized protein.	Uncharacterized protein.	0.471
Z520_03359	Z520_01387	A0A0D2KVA9	A0A0D2J0R3	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	Uncharacterized protein.	0.471
Z520_03359	Z520_01401	A0A0D2KVA9	A0A0D2HM54	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.556
Z520_03359	Z520_01800	A0A0D2KVA9	A0A0D2K6W6	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	Uncharacterized protein.	0.471
Z520_03359	Z520_04667	A0A0D2KVA9	A0A0D2KTE8	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.	0.478
Z520_03359	Z520_04688	A0A0D2KVA9	A0A0D2KA57	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	Uncharacterized protein.	0.471
Z520_03359	Z520_09890	A0A0D2KVA9	A0A0D2JVG6	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.471
Z520_03359	Z520_10286	A0A0D2KVA9	A0A0D2JU18	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	Uncharacterized protein.	0.471
Z520_03359	Z520_10883	A0A0D2KVA9	A0A0D2KAK2	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	Uncharacterized protein.	0.471
Z520_03359	Z520_11714	A0A0D2KVA9	A0A0D2K8A0	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	Uncharacterized protein.	0.471
Z520_04486	Z520_01387	A0A0D2HD89	A0A0D2J0R3	Uncharacterized protein.	Uncharacterized protein.	0.471