(35 nodes) C5-Branched dibasic acid metabolism network (Fonsecaea multimorphosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Z520_11446	Uncharacterized protein. (448 aa)
	Z520_01188	HET domain-containing protein. (434 aa)
	Z520_04485	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (388 aa)
	Z520_10878	Uncharacterized protein. (496 aa)
	Z520_01585	Uncharacterized protein. (420 aa)
	Z520_03990	Uncharacterized protein. (510 aa)
	Z520_00169	Uncharacterized protein. (415 aa)
	Z520_01858	Uncharacterized protein. (469 aa)
	Z520_08608	HET domain-containing protein. (702 aa)
	Z520_08601	Uncharacterized protein. (516 aa)
	Z520_08141	HET domain-containing protein. (562 aa)
	Z520_05629	HET domain-containing protein. (869 aa)
	Z520_01551	Zn(2)-C6 fungal-type domain-containing protein. (635 aa)
	Z520_01289	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (372 aa)
	Z520_10201	HET domain-containing protein. (642 aa)
	Z520_04315	Uncharacterized protein. (420 aa)
	Z520_04366	Uncharacterized protein. (306 aa)
	Z520_03741	Uncharacterized protein. (469 aa)
	Z520_12241	HET domain-containing protein. (131 aa)
	Z520_10881	Uncharacterized protein. (426 aa)
	Z520_10001	ACT domain-containing protein. (351 aa)
	Z520_08024	HET domain-containing protein. (601 aa)
	Z520_07085	Uncharacterized protein. (219 aa)
	Z520_05977	HET domain-containing protein. (637 aa)
	Z520_04497	Acetolactate synthase. (699 aa)
	Z520_04512	Iso_dh domain-containing protein. (363 aa)
	Z520_11797	HET domain-containing protein. (571 aa)
	Z520_11020	Uncharacterized protein. (469 aa)
	Z520_08702	HET domain-containing protein. (790 aa)
	Z520_08197	Uncharacterized protein. (498 aa)
	Z520_07086	Uncharacterized protein; Belongs to the TPP enzyme family. (564 aa)
	Z520_06520	Uncharacterized protein. (453 aa)
	Z520_09514	Uncharacterized protein. (233 aa)
	Z520_07118	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (459 aa)
	Z520_03180	Uncharacterized protein. (482 aa)

Your Current Organism:

Fonsecaea multimorphosa

NCBI taxonomy Id: 1442371
Other names: F. multimorphosa CBS 102226, Fonsecaea multimorphosa CBS 102226

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Z520_01188	Z520_01585	A0A0D2K9I3	A0A0D2KAT3	HET domain-containing protein.	Uncharacterized protein.	0.524
Z520_01188	Z520_04497	A0A0D2K9I3	A0A0D2ISA4	HET domain-containing protein.	Acetolactate synthase.	0.501
Z520_01188	Z520_07086	A0A0D2K9I3	A0A0D2JU10	HET domain-containing protein.	Uncharacterized protein; Belongs to the TPP enzyme family.	0.501
Z520_01188	Z520_10001	A0A0D2K9I3	A0A0D2IAV9	HET domain-containing protein.	ACT domain-containing protein.	0.776
Z520_01289	Z520_04497	A0A0D2L1A8	A0A0D2ISA4	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	Acetolactate synthase.	0.757
Z520_01289	Z520_07086	A0A0D2L1A8	A0A0D2JU10	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	Uncharacterized protein; Belongs to the TPP enzyme family.	0.687
Z520_01289	Z520_10001	A0A0D2L1A8	A0A0D2IAV9	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	ACT domain-containing protein.	0.866
Z520_01551	Z520_04497	A0A0D2L1Y7	A0A0D2ISA4	Zn(2)-C6 fungal-type domain-containing protein.	Acetolactate synthase.	0.523
Z520_01551	Z520_07086	A0A0D2L1Y7	A0A0D2JU10	Zn(2)-C6 fungal-type domain-containing protein.	Uncharacterized protein; Belongs to the TPP enzyme family.	0.523
Z520_01551	Z520_10001	A0A0D2L1Y7	A0A0D2IAV9	Zn(2)-C6 fungal-type domain-containing protein.	ACT domain-containing protein.	0.776
Z520_01585	Z520_01188	A0A0D2KAT3	A0A0D2K9I3	Uncharacterized protein.	HET domain-containing protein.	0.524
Z520_01585	Z520_04497	A0A0D2KAT3	A0A0D2ISA4	Uncharacterized protein.	Acetolactate synthase.	0.508
Z520_01585	Z520_07086	A0A0D2KAT3	A0A0D2JU10	Uncharacterized protein.	Uncharacterized protein; Belongs to the TPP enzyme family.	0.508
Z520_01585	Z520_10001	A0A0D2KAT3	A0A0D2IAV9	Uncharacterized protein.	ACT domain-containing protein.	0.776
Z520_04366	Z520_04497	A0A0D2HCW2	A0A0D2ISA4	Uncharacterized protein.	Acetolactate synthase.	0.523
Z520_04366	Z520_07086	A0A0D2HCW2	A0A0D2JU10	Uncharacterized protein.	Uncharacterized protein; Belongs to the TPP enzyme family.	0.523
Z520_04366	Z520_10001	A0A0D2HCW2	A0A0D2IAV9	Uncharacterized protein.	ACT domain-containing protein.	0.776
Z520_04485	Z520_04497	A0A0D2K9L1	A0A0D2ISA4	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	Acetolactate synthase.	0.615
Z520_04485	Z520_07086	A0A0D2K9L1	A0A0D2JU10	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	Uncharacterized protein; Belongs to the TPP enzyme family.	0.508
Z520_04485	Z520_10001	A0A0D2K9L1	A0A0D2IAV9	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	ACT domain-containing protein.	0.776