(32 nodes) Endoplasmic reticulum organization network (Colletotrichum fioriniae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CFIO01_13664	Uncharacterized protein. (378 aa)
	CFIO01_04270	C2 domain-containing protein. (1229 aa)
	TRM8	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (1522 aa)
	GET3	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (339 aa)
	CFIO01_05041	Uncharacterized protein. (472 aa)
	CFIO01_02350	MSP domain-containing protein. (282 aa)
	CFIO01_05470	Uncharacterized protein. (379 aa)
	CFIO01_02134	Zn(2)-C6 fungal-type domain-containing protein. (513 aa)
	CFIO01_02347	Uncharacterized protein. (436 aa)
	CFIO01_10827	Uncharacterized protein. (73 aa)
	CFIO01_02458	Uncharacterized protein. (331 aa)
	CFIO01_11912	C2 domain-containing protein. (1495 aa)
	GET1	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. (220 aa)
	CFIO01_08231	Exocyst complex component Sec3. (1401 aa)
	CFIO01_01786	Zn(2)-C6 fungal-type domain-containing protein. (501 aa)
	CFIO01_00444	Exocyst complex component SEC5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (1050 aa)
	CFIO01_07751	Reticulon-like protein. (341 aa)
	CFIO01_10051	Zn(2)-C6 fungal-type domain-containing protein. (492 aa)
	CFIO01_02381	Uncharacterized protein. (770 aa)
	CFIO01_11770	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family. (262 aa)
	CFIO01_07097	YisB protein. (271 aa)
	CFIO01_07584	Protein YOP1. (165 aa)
	CFIO01_09664	Zinc_ribbon_10 domain-containing protein. (378 aa)
	CFIO01_10634	Uncharacterized protein. (468 aa)
	CFIO01_12600	Protein YOP1. (351 aa)
	CFIO01_02712	Uncharacterized protein. (713 aa)
	CFIO01_13427	Uncharacterized protein. (732 aa)
	CFIO01_09806	Uncharacterized protein. (559 aa)
	CFIO01_10128	Uncharacterized protein. (434 aa)
	SEY1	Protein SEY1; Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. RHD3 subfamily. (847 aa)
	CFIO01_08539	Legume-like lectin family protein. (315 aa)
	CFIO01_13352	DUF2012 domain-containing protein. (175 aa)

Your Current Organism:

Colletotrichum fioriniae

NCBI taxonomy Id: 1445577
Other names: C. fioriniae PJ7, Colletotrichum fioriniae PJ7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFIO01_00444	CFIO01_08231	A0A010RDW1	A0A010RJD9	Exocyst complex component SEC5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	Exocyst complex component Sec3.	0.999
CFIO01_01786	GET1	A0A010RH15	A0A010RJH5	Zn(2)-C6 fungal-type domain-containing protein.	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	0.619
CFIO01_01786	GET3	A0A010RH15	A0A010S480	Zn(2)-C6 fungal-type domain-containing protein.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.607
CFIO01_02134	GET1	A0A010RWJ3	A0A010RJH5	Zn(2)-C6 fungal-type domain-containing protein.	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	0.619
CFIO01_02134	GET3	A0A010RWJ3	A0A010S480	Zn(2)-C6 fungal-type domain-containing protein.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.607
CFIO01_02347	CFIO01_02350	A0A010RW66	A0A010S2H3	Uncharacterized protein.	MSP domain-containing protein.	0.487
CFIO01_02347	CFIO01_02712	A0A010RW66	A0A010QW71	Uncharacterized protein.	Uncharacterized protein.	0.475
CFIO01_02347	CFIO01_11912	A0A010RW66	A0A010RMM4	Uncharacterized protein.	C2 domain-containing protein.	0.467
CFIO01_02350	CFIO01_02347	A0A010S2H3	A0A010RW66	MSP domain-containing protein.	Uncharacterized protein.	0.487
CFIO01_02350	CFIO01_02712	A0A010S2H3	A0A010QW71	MSP domain-containing protein.	Uncharacterized protein.	0.528
CFIO01_02350	CFIO01_07751	A0A010S2H3	A0A010RCS8	MSP domain-containing protein.	Reticulon-like protein.	0.578
CFIO01_02350	CFIO01_11912	A0A010S2H3	A0A010RMM4	MSP domain-containing protein.	C2 domain-containing protein.	0.570
CFIO01_02350	CFIO01_13427	A0A010S2H3	A0A010QV21	MSP domain-containing protein.	Uncharacterized protein.	0.408
CFIO01_02381	GET1	A0A010R822	A0A010RJH5	Uncharacterized protein.	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	0.423
CFIO01_02458	GET1	A0A010RNG3	A0A010RJH5	Uncharacterized protein.	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	0.662
CFIO01_02458	GET3	A0A010RNG3	A0A010S480	Uncharacterized protein.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.990
CFIO01_02712	CFIO01_02347	A0A010QW71	A0A010RW66	Uncharacterized protein.	Uncharacterized protein.	0.475
CFIO01_02712	CFIO01_02350	A0A010QW71	A0A010S2H3	Uncharacterized protein.	MSP domain-containing protein.	0.528
CFIO01_02712	CFIO01_11912	A0A010QW71	A0A010RMM4	Uncharacterized protein.	C2 domain-containing protein.	0.521
CFIO01_05041	GET1	A0A010S3S2	A0A010RJH5	Uncharacterized protein.	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	0.619