(23 nodes) MAPK cascade, and MAP kinase phosphatase activity network (Aspergillus uvarum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A319BRY6	Protein kinase domain-containing protein. (296 aa)
	A0A319BT19	Protein kinase domain-containing protein. (1616 aa)
	A0A319BVC8	Dual specificity mitogen-activated protein kinase. (644 aa)
	A0A319BVR4	Uncharacterized protein. (553 aa)
	A0A319BZA7	SH3 domain-containing protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. (290 aa)
	A0A319C3N0	Protein kinase domain-containing protein. (276 aa)
	A0A319C5E7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (365 aa)
	A0A319C9S3	Pkinase-domain-containing protein. (502 aa)
	A0A319CFX0	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (422 aa)
	A0A319CI62	Uncharacterized protein. (715 aa)
	A0A319CIN9	Alternative oxidase. (354 aa)
	A0A319CKW4	Kinase-like protein. (541 aa)
	A0A319CLE5	Von Willebrand and RING finger domain protein. (1109 aa)
	A0A319CMR0	MAPKKK cascade protein kinase regulator Ste50. (490 aa)
	A0A319CRL4	Uncharacterized protein. (139 aa)
	A0A319CRX6	MAP kinase kinase kinase. (1365 aa)
	A0A319CTZ2	Uncharacterized protein. (298 aa)
	A0A319CVY7	MADS-box domain-containing protein. (628 aa)
	A0A319CZK8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (371 aa)
	A0A319D0N3	Uncharacterized protein. (1002 aa)
	A0A319D6T9	PP2C-domain-containing protein. (571 aa)
	A0A319E1Y2	AAA_16 domain-containing protein. (1008 aa)
	A0A319E632	MAP kinase. (909 aa)

Your Current Organism:

Aspergillus uvarum

NCBI taxonomy Id: 1448315
Other names: A. uvarum CBS 121591, Aspergillus uvarum CBS 121591

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A319BRY6	A0A319BT19	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.517
A0A319BRY6	A0A319BVC8	Protein kinase domain-containing protein.	Dual specificity mitogen-activated protein kinase.	0.786
A0A319BRY6	A0A319BVR4	Protein kinase domain-containing protein.	Uncharacterized protein.	0.747
A0A319BRY6	A0A319C3N0	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.786
A0A319BRY6	A0A319C9S3	Protein kinase domain-containing protein.	Pkinase-domain-containing protein.	0.786
A0A319BRY6	A0A319CI62	Protein kinase domain-containing protein.	Uncharacterized protein.	0.733
A0A319BRY6	A0A319CIN9	Protein kinase domain-containing protein.	Alternative oxidase.	0.538
A0A319BRY6	A0A319CKW4	Protein kinase domain-containing protein.	Kinase-like protein.	0.786
A0A319BRY6	A0A319CLE5	Protein kinase domain-containing protein.	Von Willebrand and RING finger domain protein.	0.485
A0A319BRY6	A0A319CRL4	Protein kinase domain-containing protein.	Uncharacterized protein.	0.485
A0A319BRY6	A0A319CRX6	Protein kinase domain-containing protein.	MAP kinase kinase kinase.	0.583
A0A319BRY6	A0A319CTZ2	Protein kinase domain-containing protein.	Uncharacterized protein.	0.733
A0A319BRY6	A0A319CVY7	Protein kinase domain-containing protein.	MADS-box domain-containing protein.	0.921
A0A319BRY6	A0A319D0N3	Protein kinase domain-containing protein.	Uncharacterized protein.	0.747
A0A319BRY6	A0A319D6T9	Protein kinase domain-containing protein.	PP2C-domain-containing protein.	0.733
A0A319BRY6	A0A319E1Y2	Protein kinase domain-containing protein.	AAA_16 domain-containing protein.	0.517
A0A319BRY6	A0A319E632	Protein kinase domain-containing protein.	MAP kinase.	0.517
A0A319BT19	A0A319BRY6	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.517
A0A319BT19	A0A319BVC8	Protein kinase domain-containing protein.	Dual specificity mitogen-activated protein kinase.	0.926
A0A319BT19	A0A319BZA7	Protein kinase domain-containing protein.	SH3 domain-containing protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	0.844