(47 nodes) Reproduction of a single-celled organism network (Aspergillus uvarum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A319BS69	Mannan endo-1,6-alpha-mannosidase. (456 aa)
	A0A319BT78	Mannan endo-1,6-alpha-mannosidase. (444 aa)
	A0A319BUD8	Phospholipase. (1830 aa)
	A0A319BYV1	DUF602-domain-containing protein. (335 aa)
	A0A319BZW2	Glyco_trans_2-like domain-containing protein. (578 aa)
	A0A319C046	Uncharacterized protein. (474 aa)
	A0A319C146	EF-hand. (315 aa)
	A0A319C184	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	A0A319C234	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa)
	A0A319C2C8	Phospholipase. (835 aa)
	A0A319C4A4	Putative phosphatidylinositol transporter. (315 aa)
	A0A319C5P1	Serine/threonine protein kinase. (648 aa)
	A0A319C6P0	Uncharacterized protein. (310 aa)
	A0A319C8F2	Peroxin/Ferlin domain-containing protein. (485 aa)
	A0A319C8S6	Chitin synthase D. (1192 aa)
	A0A319C909	Glycosyl transferase. (377 aa)
	A0A319C9I3	Polysaccharide deacetylase family protein. (249 aa)
	A0A319C9N7	SAICAR synthase-like protein. (342 aa)
	A0A319CCM7	AIP3-domain-containing protein. (1044 aa)
	A0A319CD79	Polyadenylate-binding protein. (498 aa)
	A0A319CES8	Mannan endo-1,6-alpha-mannosidase. (461 aa)
	A0A319CF93	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
	A0A319CFK3	Uncharacterized protein. (949 aa)
	A0A319CFZ8	Six-hairpin glycosidase. (387 aa)
	A0A319CGG2	Plasma membrane fusion protein PRM1; Involved in cell fusion during mating by stabilizing the plasma membrane fusion event; Belongs to the PRM1 family. (763 aa)
	A0A319CHR5	Uncharacterized protein. (271 aa)
	A0A319CHW5	Uncharacterized protein. (527 aa)
	A0A319CJ51	Mannan endo-1,6-alpha-mannosidase. (422 aa)
	A0A319CJK2	Six-hairpin glycosidase. (369 aa)
	A0A319CJT4	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1131 aa)
	A0A319CJX5	Phospholipase. (1308 aa)
	A0A319CK63	Uncharacterized protein. (839 aa)
	A0A319CKD0	Cell division control protein 42. (192 aa)
	A0A319CL69	Mannan endo-1,6-alpha-mannosidase. (446 aa)
	A0A319CM88	Non-specific serine/threonine protein kinase. (832 aa)
	A0A319CMC7	Trehalose-6-phosphate synthase. (509 aa)
	A0A319CMK2	Uncharacterized protein. (164 aa)
	uba4	Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (477 aa)
	A0A319CR00	Serine/threonine-protein phosphatase. (264 aa)
	A0A319CWM7	Uncharacterized protein. (786 aa)
	A0A319CYW1	Multicopy suppressor of Stt4 mutation. (866 aa)
	A0A319D1T9	Non-specific serine/threonine protein kinase. (847 aa)
	A0A319D9X3	Mannan endo-1,6-alpha-mannosidase. (460 aa)
	A0A319DCF9	Histidine kinase. (712 aa)
	A0A319DDV3	Pterin-4-alpha-carbinolamine dehydratase. (204 aa)
	A0A319DUH7	Conidiophore development protein HymA. (383 aa)
	A0A319DWU8	Putative cytochrome P450 oxidoreductase; Belongs to the cytochrome P450 family. (503 aa)

Your Current Organism:

Aspergillus uvarum

NCBI taxonomy Id: 1448315
Other names: A. uvarum CBS 121591, Aspergillus uvarum CBS 121591

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A319BUD8	A0A319C2C8	Phospholipase.	Phospholipase.	0.882
A0A319BUD8	A0A319C4A4	Phospholipase.	Putative phosphatidylinositol transporter.	0.692
A0A319BUD8	A0A319CJX5	Phospholipase.	Phospholipase.	0.887
A0A319BUD8	A0A319CKD0	Phospholipase.	Cell division control protein 42.	0.743
A0A319C046	A0A319CJ51	Uncharacterized protein.	Mannan endo-1,6-alpha-mannosidase.	0.400
A0A319C046	A0A319CL69	Uncharacterized protein.	Mannan endo-1,6-alpha-mannosidase.	0.424
A0A319C184	A0A319C234	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.753
A0A319C184	A0A319C6P0	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.478
A0A319C184	A0A319CF93	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.581
A0A319C184	A0A319CK63	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.478
A0A319C184	A0A319CKD0	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Cell division control protein 42.	0.850
A0A319C184	A0A319CM88	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Non-specific serine/threonine protein kinase.	0.402
A0A319C184	A0A319CR00	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Serine/threonine-protein phosphatase.	0.624
A0A319C184	A0A319D1T9	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Non-specific serine/threonine protein kinase.	0.402
A0A319C234	A0A319C184	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.753
A0A319C234	A0A319C6P0	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Uncharacterized protein.	0.405
A0A319C234	A0A319C9N7	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	SAICAR synthase-like protein.	0.513
A0A319C234	A0A319CF93	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.573
A0A319C234	A0A319CK63	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Uncharacterized protein.	0.405
A0A319C234	A0A319CKD0	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Cell division control protein 42.	0.870