(28 nodes) Nervous system development network (Aspergillus uvarum)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	A0A319CCK3	AP-2 complex subunit MU; Belongs to the adaptor complexes medium subunit family. (456 aa)
	A0A319BVC8	Dual specificity mitogen-activated protein kinase. (644 aa)
	A0A319BXT2	Uncharacterized protein. (160 aa)
	A0A319BYQ9	Ubiquitin-like protein. (250 aa)
	A0A319C0F6	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (930 aa)
	A0A319C0X2	C6 finger domain protein. (862 aa)
	A0A319C254	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (717 aa)
	A0A319C3N0	Protein kinase domain-containing protein. (276 aa)
	A0A319C454	Zn(2)-C6 fungal-type domain-containing protein. (632 aa)
	A0A319C7M7	WH1-domain-containing protein. (699 aa)
	A0A319C9S3	Pkinase-domain-containing protein. (502 aa)
	A0A319BQX8	Fungal_trans domain-containing protein. (416 aa)
	A0A319CDC3	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (145 aa)
	SLX4	Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (846 aa)
	A0A319CJJ1	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1676 aa)
	A0A319CK18	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (746 aa)
	A0A319CKW4	Kinase-like protein. (541 aa)
	A0A319CPE2	Allantoinase. (495 aa)
	A0A319CPE3	Cofilin; Belongs to the actin-binding proteins ADF family. (155 aa)
	A0A319CPQ5	Tryptophanase. (460 aa)
	A0A319CXZ9	Endo-polygalacturonase D. (490 aa)
	A0A319CYZ8	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (249 aa)
	A0A319CZK8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (371 aa)
	A0A319D403	Metallo-dependent hydrolase. (313 aa)
	A0A319D7X8	Cofilin, actophorin; Belongs to the actin-binding proteins ADF family. (150 aa)
	A0A319D879	Amidohydro-rel domain-containing protein. (453 aa)
	A0A319DN66	Cell division control protein 42. (199 aa)
	A0A319DWG0	Actin depolymerizing protein; Belongs to the actin-binding proteins ADF family. (116 aa)

Your Current Organism:

Aspergillus uvarum

NCBI taxonomy Id: 1448315
Other names: A. uvarum CBS 121591, Aspergillus uvarum CBS 121591

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A319BQX8	A0A319C0F6	A0A319BQX8	A0A319C0F6	Fungal_trans domain-containing protein.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.653
A0A319BVC8	A0A319C9S3	A0A319BVC8	A0A319C9S3	Dual specificity mitogen-activated protein kinase.	Pkinase-domain-containing protein.	0.545
A0A319BVC8	A0A319CKW4	A0A319BVC8	A0A319CKW4	Dual specificity mitogen-activated protein kinase.	Kinase-like protein.	0.860
A0A319BVC8	A0A319CZK8	A0A319BVC8	A0A319CZK8	Dual specificity mitogen-activated protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.947
A0A319BVC8	A0A319DN66	A0A319BVC8	A0A319DN66	Dual specificity mitogen-activated protein kinase.	Cell division control protein 42.	0.543
A0A319BYQ9	A0A319C0F6	A0A319BYQ9	A0A319C0F6	Ubiquitin-like protein.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.937
A0A319BYQ9	A0A319CCK3	A0A319BYQ9	A0A319CCK3	Ubiquitin-like protein.	AP-2 complex subunit MU; Belongs to the adaptor complexes medium subunit family.	0.963
A0A319BYQ9	A0A319CDC3	A0A319BYQ9	A0A319CDC3	Ubiquitin-like protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.954
A0A319BYQ9	A0A319CJJ1	A0A319BYQ9	A0A319CJJ1	Ubiquitin-like protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.954
A0A319BYQ9	A0A319CYZ8	A0A319BYQ9	A0A319CYZ8	Ubiquitin-like protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.878
A0A319BYQ9	A0A319CZK8	A0A319BYQ9	A0A319CZK8	Ubiquitin-like protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.538
A0A319BYQ9	A0A319DN66	A0A319BYQ9	A0A319DN66	Ubiquitin-like protein.	Cell division control protein 42.	0.479
A0A319C0F6	A0A319BQX8	A0A319C0F6	A0A319BQX8	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Fungal_trans domain-containing protein.	0.653
A0A319C0F6	A0A319BYQ9	A0A319C0F6	A0A319BYQ9	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Ubiquitin-like protein.	0.937
A0A319C0F6	A0A319C254	A0A319C0F6	A0A319C254	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.977
A0A319C0F6	A0A319C454	A0A319C0F6	A0A319C454	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Zn(2)-C6 fungal-type domain-containing protein.	0.653
A0A319C0F6	A0A319CCK3	A0A319C0F6	A0A319CCK3	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP-2 complex subunit MU; Belongs to the adaptor complexes medium subunit family.	0.996
A0A319C0F6	A0A319CDC3	A0A319C0F6	A0A319CDC3	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.996
A0A319C0F6	A0A319CJJ1	A0A319C0F6	A0A319CJJ1	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.863
A0A319C0F6	A0A319CK18	A0A319C0F6	A0A319CK18	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.937